The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer
出版年份 2018 全文链接
标题
The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer
作者
关键词
Colon, Adenomas, Epithelium, Colorectal cancer, Mouse models, Antigen-presenting cells, Cancer treatment, Inflammatory bowel disease
出版物
PLoS Genetics
Volume 14, Issue 9, Pages e1007611
出版商
Public Library of Science (PLoS)
发表日期
2018-09-07
DOI
10.1371/journal.pgen.1007611
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia
- (2016) Badar Mahmood et al. BMC CANCER
- Genomic Landscape of Colorectal Mucosa and Adenomas
- (2016) E. Borras et al. Cancer Prevention Research
- Evaluating the evaluation of cancer driver genes
- (2016) Collin J. Tokheim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification
- (2016) Jong Ho Park et al. Nature Communications
- Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma
- (2016) Marios Giannakis et al. Cell Reports
- A multi-functional analyzer uses parameter constraints to improve the efficiency of model-based gene-set analysis
- (2015) Zhishi Wang et al. Annals of Applied Statistics
- Phosphodiesterase sequence variants may predispose to prostate cancer
- (2015) Rodrigo B de Alexandre et al. ENDOCRINE-RELATED CANCER
- A phosphodiesterase 4B-dependent interplay between tumor cells and the microenvironment regulates angiogenesis in B-cell lymphoma
- (2015) A N Suhasini et al. LEUKEMIA
- APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice
- (2015) T-L Kuo et al. ONCOGENE
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice
- (2014) A. Stoddart et al. BLOOD
- The utility ofApc-mutant rats in modeling human colon cancer
- (2014) Amy A. Irving et al. Disease Models & Mechanisms
- Multifocal epithelial tumors and field cancerization: stroma as a primary determinant
- (2014) G. Paolo Dotto JOURNAL OF CLINICAL INVESTIGATION
- Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones
- (2014) James M. Amos-Landgraf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer
- (2013) Arantza Fariña Sarasqueta et al. BMC CANCER
- Pathology of Rodent Models of Intestinal Cancer: Progress Report and Recommendations
- (2013) Mary Kay Washington et al. GASTROENTEROLOGY
- Expression Profiling of Proliferation and Apoptotic Markers along the Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis Patients
- (2013) Jayson Wang et al. Gastroenterology Research and Practice
- Limited Agreement of Independent RNAi Screens for Virus-Required Host Genes Owes More to False-Negative than False-Positive Factors
- (2013) Linhui Hao et al. PLoS Computational Biology
- Field cancerization in mammary carcinogenesis — Implications for prevention and treatment of breast cancer
- (2012) Ashley G. Rivenbark et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms
- (2012) J. M. Amos-Landgraf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Regulated Expression of Chromobox Homolog 5 Revealed in Tumors of Apc Min /+ ROSA11 Gene Trap Mice
- (2012) Andrew T. Thliveris et al. G3-Genes Genomes Genetics
- Spatial control of cAMP signalling in health and disease
- (2011) Manuela Zaccolo CURRENT OPINION IN PHARMACOLOGY
- Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis
- (2011) Susan Galandiuk et al. GASTROENTEROLOGY
- A continuum model for tumour suppression
- (2011) Alice H. Berger et al. NATURE
- New insights into oncogenic stress
- (2011) Kevin M Haigis et al. NATURE GENETICS
- Downregulation of phosphodiesterase 4B (PDE4B) activates protein kinase A and contributes to the progression of prostate cancer
- (2011) Eiji Kashiwagi et al. PROSTATE
- Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq
- (2010) Daniel Bottomly et al. NUCLEIC ACIDS RESEARCH
- Aberrant DNA methylation profile of hepatocellular carcinoma and surgically resected margin
- (2009) Cheng Lou et al. CANCER SCIENCE
- The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
- (2009) S. A. Bustin et al. CLINICAL CHEMISTRY
- Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases
- (2009) Aron M. Geurts et al. SCIENCE
- PDE4 inhibitors: current status
- (2008) D Spina BRITISH JOURNAL OF PHARMACOLOGY
- Cellular Expression Patterns of Genes Upregulated in Murine and Human Colonic Neoplasms
- (2008) Xiaodi Chen et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
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