Genes regulated by SATB2 during neurodevelopment contribute to schizophrenia and educational attainment

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS

(2017) Akintomide Apara et al.   JOURNAL OF NEUROSCIENCE

Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

(2017) Hsiang-Chih Lu et al.   NATURE GENETICS

Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c

(2017) Kacey E. Rajkovich et al.   NEURON

Novel genetic loci associated with hippocampal volume

(2017) Derrek P. Hibar et al.   Nature Communications

DRD2 co-expression network and a related polygenic index predict imaging, behavioral and clinical phenotypes linked to schizophrenia

(2017) G Pergola et al.   Translational Psychiatry

Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules

(2016) Korinna Kochinke et al.   AMERICAN JOURNAL OF HUMAN GENETICS

SATB2-associated syndrome: Mechanisms, phenotype, and practical recommendations

(2016) Yuri A. Zarate et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Genome-wide association study identifies 74 loci associated with educational attainment

(2016) Aysu Okbay et al.   NATURE

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Novel genetic loci underlying human intracranial volume identified through genome-wide association

(2016) Hieab H H Adams et al.   NATURE NEUROSCIENCE

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

(2016) Giulio Genovese et al.   NATURE NEUROSCIENCE

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

(2016) Yi-Chuan Chen et al.   NATURE NEUROSCIENCE

Analyzing and interpreting genome data at the network level with ConsensusPathDB

(2016) Ralf Herwig et al.   Nature Protocols

The statistical properties of gene-set analysis

(2016) Christiaan A. de Leeuw et al.   NATURE REVIEWS GENETICS

Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B

(2016) Divya Punwani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Satb2 determines miRNA expression and long-term memory in the adult central nervous system

(2016) Clemens Jaitner et al.   eLife

Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

(2016) Kawssar Harb et al.   eLife

Structure and function insights into the NuRD chromatin remodeling complex

(2015) Morgan P. Torchy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mutual regulation betweenSatb2andFezf2promotes subcerebral projection neuron identity in the developing cerebral cortex

(2015) William L. McKenna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Expression of Transcription Factor Satb2 in Adult Mouse Brain

(2014) Ying Huang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality

(2014) Tzyy-Nan Huang et al.   NATURE NEUROSCIENCE

Laf4/Aff3, a Gene Involved in Intellectual Disability, Is Required for Cellular Migration in the Mouse Cerebral Cortex

(2014) Justin M. Moore et al.   PLoS One

Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation

(2014) Swathi Srivatsa et al.   Nature Communications

Further delineation of the SATB2 phenotype

(2013) Dennis Döcker et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons

(2013) Jennifer Betancourt et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)

(2013) T Lencz et al.   MOLECULAR PSYCHIATRY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries

(2012) Michael E. Talkowski et al.   CELL

The AT-rich DNA-binding Protein SATB2 Promotes Expression and Physical Association of HumanGγ- andAγ-GlobinGenes

(2012) Li-Quan Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small-conductance Ca2+-activated K+ channels modulate action potential-induced Ca2+ transients in hippocampal neurons

(2012) Raffaella Tonini et al.   JOURNAL OF NEUROPHYSIOLOGY

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

(2012) Matthew Traylor et al.   LANCET NEUROLOGY

Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons

(2012) C. Baranek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A network of genetic repression and derepression specifies projection fates in the developing neocortex

(2012) K. Srinivasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Satb2 Is Required for Dendritic Arborization and Soma Spacing in Mouse Cerebral Cortex

(2011) Lei Zhang et al.   CEREBRAL CORTEX

Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation

(2011) J. R. Leslie et al.   DEVELOPMENT

Tbr1 and Fezf2 Regulate Alternate Corticofugal Neuronal Identities during Neocortical Development

(2011) W. L. McKenna et al.   JOURNAL OF NEUROSCIENCE

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Maximal brain size remains an important predictor of cognition in old age, independent of current brain pathology

(2011) Sarah Tomaszewski Farias et al.   NEUROBIOLOGY OF AGING

The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice

(2011) Kenzi Saito et al.   Molecular Brain

Foxp2 Regulates Gene Networks Implicated in Neurite Outgrowth in the Developing Brain

(2011) Sonja C. Vernes et al.   PLoS Genetics

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice

(2009) Michael Piper et al.   Neural Development

Satb2 Is a Postmitotic Determinant for Upper-Layer Neuron Specification in the Neocortex

(2008) Olga Britanova et al.   NEURON

Satb2 Regulates Callosal Projection Neuron Identity in the Developing Cerebral Cortex

(2008) Elizabeth A. Alcamo et al.   NEURON