标题
The Mycobacterium tuberculosis Drugome and Its Polypharmacological Implications
作者
关键词
-
出版物
PLoS Computational Biology
Volume 6, Issue 11, Pages e1000976
出版商
Public Library of Science (PLoS)
发表日期
2010-11-05
DOI
10.1371/journal.pcbi.1000976
参考文献
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- (2010) Francisco-Javier Gamo et al. NATURE
- Chemical genetics of Plasmodium falciparum
- (2010) W. Armand Guiguemde et al. NATURE
- Modular architecture of nucleotide-binding pockets
- (2010) Pier Federico Gherardini et al. NUCLEIC ACIDS RESEARCH
- A Multidimensional Strategy to Detect Polypharmacological Targets in the Absence of Structural and Sequence Homology
- (2010) Jacob D. Durrant et al. PLoS Computational Biology
- Protein Kinase G Is Required for Intrinsic Antibiotic Resistance in Mycobacteria
- (2009) K. A. Wolff et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A unified statistical model to support local sequence order independent similarity searching for ligand-binding sites and its application to genome-based drug discovery
- (2009) L. Xie et al. BIOINFORMATICS
- Aligning Antimicrobial Drug Discovery with Complex and Redundant Host-Pathogen Interactions
- (2009) Sarah L. Lebeis et al. Cell Host & Microbe
- Nothing about protein structure classification makes sense except in the light of evolution
- (2009) Ruben E Valas et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The topology of drug–target interaction networks: implicit dependence on drug properties and target families
- (2009) Jordi Mestres et al. Molecular BioSystems
- Alignment-Free Prediction of a Drug−Target Complex Network Based on Parameters of Drug Connectivity and Protein Sequence of Receptors
- (2009) Dolores Viña et al. MOLECULAR PHARMACEUTICS
- Predicting new molecular targets for known drugs
- (2009) Michael J. Keiser et al. NATURE
- Protein promiscuity and its implications for biotechnology
- (2009) Irene Nobeli et al. NATURE BIOTECHNOLOGY
- Drug interactions and the evolution of antibiotic resistance
- (2009) Pamela J. Yeh et al. NATURE REVIEWS MICROBIOLOGY
- A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore
- (2009) J. Richard Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting a bacterial stress response to enhance antibiotic action
- (2009) S. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drug Discovery Using Chemical Systems Biology: Repositioning the Safe Medicine Comtan to Treat Multi-Drug and Extensively Drug Resistant Tuberculosis
- (2009) Sarah L. Kinnings et al. PLoS Computational Biology
- Integrating Statistical Predictions and Experimental Verifications for Enhancing Protein-Chemical Interaction Predictions in Virtual Screening
- (2009) Nobuyoshi Nagamine et al. PLoS Computational Biology
- FINDSITELHM: A Threading-Based Approach to Ligand Homology Modeling
- (2009) Michal Brylinski et al. PLoS Computational Biology
- Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors
- (2009) Li Xie et al. PLoS Computational Biology
- Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP-Binding: Requirement for Establishing Chronic Persistent Infection
- (2009) Joshua E. Drumm et al. PLoS Pathogens
- Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway
- (2008) Hao Lu et al. ACCOUNTS OF CHEMICAL RESEARCH
- 1.9 Å structure of the signal receiver domain of the putative response regulator NarL fromMycobacterium tuberculosis
- (2008) Robert Schnell et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Prediction of drug-target interaction networks from the integration of chemical and genomic spaces
- (2008) Y. Yamanishi et al. BIOINFORMATICS
- A Ligand-Based Approach to Mining the Chemogenomic Space of Drugs
- (2008) Elisabet Gregori-Puigjane et al. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- Data completeness—the Achilles heel of drug-target networks
- (2008) Jordi Mestres et al. NATURE BIOTECHNOLOGY
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- Genomic-scale prioritization of drug targets: the TDR Targets database
- (2008) Fernán Agüero et al. NATURE REVIEWS DRUG DISCOVERY
- MODBASE, a database of annotated comparative protein structure models and associated resources
- (2008) U. Pieper et al. NUCLEIC ACIDS RESEARCH
- Detecting evolutionary relationships across existing fold space, using sequence order-independent profile-profile alignments
- (2008) L. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr
- (2008) J. Baysarowich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting QseC Signaling and Virulence for Antibiotic Development
- (2008) D. A. Rasko et al. SCIENCE
- Drug Target Identification Using Side-Effect Similarity
- (2008) M. Campillos et al. SCIENCE
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