Mice, men and the relatives: cross-species studies underpin innate immunity

NAIP and Ipaf Control Legionella pneumophila Replication in Human Cells

(2014) M. Vinzing et al.   JOURNAL OF IMMUNOLOGY

Elucidation of the MD-2/TLR4 Interface Required for Signaling by Lipid IVa

(2014) C. Walsh et al.   JOURNAL OF IMMUNOLOGY

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Application of hybrid LRR technique to protein crystallization

(2011) Mi-Sun Jin et al.   BMB Reports

Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA

(2011) Eva Kowalinski et al.   CELL

Sensing disease and danger: A survey of vertebrate PRRs and their origins

(2011) John D. Hansen et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

The PYHIN protein family as mediators of host defenses

(2011) Stefan A. Schattgen et al.   IMMUNOLOGICAL REVIEWS

RIG-I-like receptors: cytoplasmic sensors for non-self RNA

(2011) Hiroki Kato et al.   IMMUNOLOGICAL REVIEWS

Molecular Evolution of the Toll-Like Receptor Multigene Family in Birds

(2011) M. Alcaide et al.   MOLECULAR BIOLOGY AND EVOLUTION

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

The genome sequence of Atlantic cod reveals a unique immune system

(2011) Bastiaan Star et al.   NATURE

NLR functions beyond pathogen recognition

(2011) Thomas A Kufer et al.   NATURE IMMUNOLOGY

NLR functions in plant and animal immune systems: so far and yet so close

(2011) Takaki Maekawa et al.   NATURE IMMUNOLOGY

Comparative Analysis of Species-Specific Ligand Recognition in Toll-Like Receptor 8 Signaling: A Hypothesis

(2011) Rajiv Gandhi Govindaraj et al.   PLoS One

The 2011 Nobel Prize in Physiology or Medicine

(2011) Roman Volchenkov et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Domain architecture evolution of pattern-recognition receptors

(2010) Qing Zhang et al.   IMMUNOGENETICS

Defining the Origins of the NOD-Like Receptor System at the Base of Animal Evolution

(2010) C. Lange et al.   MOLECULAR BIOLOGY AND EVOLUTION

Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel

(2010) Marc Schmidt et al.   NATURE IMMUNOLOGY

Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA

(2010) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Expression of the avian-specific toll-like receptor 15 in chicken heterophils is mediated by Gram-negative and Gram-positive bacteria, but not TLR agonists

(2010) Jessica R. Nerren et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Duplication of the caspase-12 prodomain and inactivation of NLRC4/IPAF in the dog

(2009) Leopold Eckhart et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evolution and functional divergence of NLRP genes in mammalian reproductive systems

(2009) Xin Tian et al.   BMC EVOLUTIONARY BIOLOGY

Recognition of Lipopeptide Patterns by Toll-like Receptor 2-Toll-like Receptor 6 Heterodimer

(2009) Jin Young Kang et al.   IMMUNITY

Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity

(2009) Susannah D. Brydges et al.   IMMUNITY

Evolution of Lipopolysaccharide (LPS) Recognition and Signaling: Fish TLR4 Does Not Recognize LPS and Negatively Regulates NF- B Activation

(2009) M. P. Sepulcre et al.   JOURNAL OF IMMUNOLOGY

Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides

(2009) Robert Brownlie et al.   MOLECULAR IMMUNOLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

The molecular basis of the host response to lipopolysaccharide

(2009) Clare E. Bryant et al.   NATURE REVIEWS MICROBIOLOGY

A Novel Protein Isoform of the Multicopy Human NAIP Gene Derives from Intragenic Alu SINE Promoters

(2009) Mark T. Romanish et al.   PLoS One

Variation matters: TLR structure and species-specific pathogen recognition

(2009) Dirk Werling et al.   TRENDS IN IMMUNOLOGY

Toll-like receptor signaling in bony fish

(2009) Alexander Rebl et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish

(2008) Kerry J Laing et al.   BMC EVOLUTIONARY BIOLOGY

Evolution of the chicken Toll-like receptor gene family: A story of gene gain and gene loss

(2008) Nicholas D Temperley et al.   BMC GENOMICS

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

Toll-like receptors — taking an evolutionary approach

(2008) François Leulier et al.   NATURE REVIEWS GENETICS

Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

(2008) L. Liu et al.   SCIENCE

Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-1 (NOD1) recognizing minimum agonists, meso-diaminopimelic acid and meso-lanthionine

(2007) Masanori Tohno et al.   MOLECULAR IMMUNOLOGY