NLR functions in plant and animal immune systems: so far and yet so close

Programmed cell death in the plant immune system

(2011) N S Coll et al.   CELL DEATH AND DIFFERENTIATION

Specific Threonine Phosphorylation of a Host Target by Two Unrelated Type III Effectors Activates a Host Innate Immune Receptor in Plants

(2011) Eui-Hwan Chung et al.   Cell Host & Microbe

A Receptor-like Cytoplasmic Kinase Phosphorylates the Host Target RIN4, Leading to the Activation of a Plant Innate Immune Receptor

(2011) Jun Liu et al.   Cell Host & Microbe

Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation

(2011) Maud Bernoux et al.   Cell Host & Microbe

Coiled-Coil Domain-Dependent Homodimerization of Intracellular Barley Immune Receptors Defines a Minimal Functional Module for Triggering Cell Death

(2011) Takaki Maekawa et al.   Cell Host & Microbe

Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity

(2011) Steffen Rietz et al.   NEW PHYTOLOGIST

Wheat gene bank accessions as a source of new alleles of the powdery mildew resistance gene Pm3: a large scale allele mining project

(2010) Navreet K Bhullar et al.   BMC PLANT BIOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Crystal Structure of the Caenorhabditis elegans Apoptosome Reveals an Octameric Assembly of CED-4

(2010) Shiqian Qi et al.   CELL

NB-LRR proteins: pairs, pieces, perception, partners, and pathways

(2010) Timothy K Eitas et al.   CURRENT OPINION IN PLANT BIOLOGY

Domain architecture evolution of pattern-recognition receptors

(2010) Qing Zhang et al.   IMMUNOGENETICS

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Defining the Origins of the NOD-Like Receptor System at the Base of Animal Evolution

(2010) C. Lange et al.   MOLECULAR BIOLOGY AND EVOLUTION

Unique evolutionary pattern of numbers of gramineous NBS–LRR genes

(2010) Jing Li et al.   MOLECULAR GENETICS AND GENOMICS

Co-evolutionary interactions between host resistance and pathogen effector genes in flax rust disease

(2010) MICHAEL RAVENSDALE et al.   MOLECULAR PLANT PATHOLOGY

Diversity at theMlaPowdery Mildew Resistance Locus from Cultivated Barley Reveals Sites of Positive Selection

(2010) Sabine Seeholzer et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

RanGAP2 Mediates Nucleocytoplasmic Partitioning of the NB-LRR Immune Receptor Rx in the Solanaceae, Thereby Dictating Rx Function

(2010) Wladimir I.L. Tameling et al.   PLANT CELL

Nucleocytoplasmic Distribution Is Required for Activation of Resistance by the Potato NB-LRR Receptor Rx1 and Is Balanced by Its Functional Domains

(2010) Erik Slootweg et al.   PLANT CELL

Activation of an Arabidopsis Resistance Protein Is Specified by the in Planta Association of Its Leucine-Rich Repeat Domain with the Cognate Oomycete Effector

(2010) K. V. Krasileva et al.   PLANT CELL

Arabidopsis and the plant immune system

(2010) Marc T. Nishimura et al.   PLANT JOURNAL

The CC-NB-LRR-Type Rdg2a Resistance Gene Confers Immunity to the Seed-Borne Barley Leaf Stripe Pathogen in the Absence of Hypersensitive Cell Death

(2010) Davide Bulgarelli et al.   PLoS One

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes

(2010) T. B. Meissner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis resistance protein SNC1 activates immune responses through association with a transcriptional corepressor

(2010) Z. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signatures of Adaptation to Obligate Biotrophy in the Hyaloperonospora arabidopsidis Genome

(2010) L. Baxter et al.   SCIENCE

Pathogenicity Determinants in Smut Fungi Revealed by Genome Comparison

(2010) J. Schirawski et al.   SCIENCE

Genome Evolution Following Host Jumps in the Irish Potato Famine Pathogen Lineage

(2010) S. Raffaele et al.   SCIENCE

Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism

(2010) P. D. Spanu et al.   SCIENCE

Arabidopsis Type I Metacaspases Control Cell Death

(2010) N. S. Coll et al.   SCIENCE

Structure of an Apoptosome-Procaspase-9 CARD Complex

(2010) Shujun Yuan et al.   STRUCTURE

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii

(2010) Tobias Steinfeldt et al.   PLOS BIOLOGY

The Arabidopsis Resistance-Like Gene SNC1 Is Activated by Mutations in SRFR1 and Contributes to Resistance to the Bacterial Effector AvrRps4

(2010) Sang Hee Kim et al.   PLoS Pathogens

SRFR1 Negatively Regulates Plant NB-LRR Resistance Protein Accumulation to Prevent Autoimmunity

(2010) Yingzhong Li et al.   PLoS Pathogens

Balanced Nuclear and Cytoplasmic Activities of EDS1 Are Required for a Complete Plant Innate Immune Response

(2010) Ana V. García et al.   PLoS Pathogens

A Renaissance of Elicitors: Perception of Microbe-Associated Molecular Patterns and Danger Signals by Pattern-Recognition Receptors

(2009) Thomas Boller et al.   Annual Review of Plant Biology

The Fractionated Orthology of Bs2 and Rx / Gpa2 Supports Shared Synteny of Disease Resistance in the Solanaceae

(2009) Michael Mazourek et al.   GENETICS

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Maintenance of genetic variation in plants and pathogens involves complex networks of gene-for-gene interactions

(2009) SHARON A. HALL et al.   MOLECULAR PLANT PATHOLOGY

Relationships between rust resistance genes at theMlocus in flax

(2009) GREGORY J. LAWRENCE et al.   MOLECULAR PLANT PATHOLOGY

The TIR Domain of TIR-NB-LRR Resistance Proteins Is a Signaling Domain Involved in Cell Death Induction

(2009) Michal R. Swiderski et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans

(2009) Brian J. Haas et al.   NATURE

Networking by small-molecule hormones in plant immunity

(2009) Corné M J Pieterse et al.   Nature Chemical Biology

Nuclear Pore Complex Component MOS7/Nup88 Is Required for Innate Immunity and Nuclear Accumulation of Defense Regulators in Arabidopsis

(2009) Y. T. Cheng et al.   PLANT CELL

RRS1andRPS4provide a dualResistance-gene system against fungal and bacterial pathogens

(2009) Mari Narusaka et al.   PLANT JOURNAL

Prf immune complexes of tomato are oligomeric and contain multiple Pto-like kinases that diversify effector recognition

(2009) Jose R. Gutierrez et al.   PLANT JOURNAL

Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

(2009) H. Ohnishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune sensing and activation of cell surface Toll-like receptors

(2009) Richard I. Tapping   SEMINARS IN IMMUNOLOGY

Wheel of Life, Wheel of Death: A Mechanistic Insight into Signaling by STAND Proteins

(2009) Olivier Danot et al.   STRUCTURE

NB-LRRs work a “bait and switch” on pathogens

(2009) Sarah M. Collier et al.   TRENDS IN PLANT SCIENCE

Network Properties of Robust Immunity in Plants

(2009) Kenichi Tsuda et al.   PLoS Genetics

The HSP90-SGT1 Chaperone Complex for NLR Immune Sensors

(2008) Ken Shirasu   Annual Review of Plant Biology

Monomer/Dimer Transition of the Caspase-Recruitment Domain of Human Nod1†,‡

(2008) Thiagarajan Srimathi et al.   BIOCHEMISTRY

Chloroplastic Protein NRIP1 Mediates Innate Immune Receptor Recognition of a Viral Effector

(2008) Jeffrey L. Caplan et al.   CELL

Bacterial Effectors Target the Common Signaling Partner BAK1 to Disrupt Multiple MAMP Receptor-Signaling Complexes and Impede Plant Immunity

(2008) Libo Shan et al.   Cell Host & Microbe

Pseudomonas syringae Effector AvrPto Blocks Innate Immunity by Targeting Receptor Kinases

(2008) Tingting Xiang et al.   CURRENT BIOLOGY

Signal transduction pathways used by NLR-type innate immune receptors

(2008) Thomas A. Kufer   Molecular BioSystems

The Coiled-Coil and Nucleotide Binding Domains of the Potato Rx Disease Resistance Protein Function in Pathogen Recognition and Signaling

(2008) G. J. Rairdan et al.   PLANT CELL

From Guard to Decoy: A New Model for Perception of Plant Pathogen Effectors

(2008) R. A.L. van der Hoorn et al.   PLANT CELL

Frequent sequence exchanges between homologs of RPP8 in Arabidopsis are not necessarily associated with genomic proximity

(2008) Hanhui Kuang et al.   PLANT JOURNAL

SRFR1, a suppressor of effector-triggered immunity, encodes a conserved tetratricopeptide repeat protein with similarity to transcriptional repressors

(2008) Soon Il Kwon et al.   PLANT JOURNAL

The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences

(2008) Martina Proell et al.   PLoS One

Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB

(2008) T. K. Eitas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1  secretion in response to Bacillus anthracis infection and muramyl dipeptide

(2008) L.-C. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP2 contributes to Nod signaling but is not essential for T cell proliferation, T helper differentiation or TLR responses

(2007) Håkan T. L. Hall et al.   EUROPEAN JOURNAL OF IMMUNOLOGY