Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

(2015) Bo Young Choi et al.   Journal of Neuroinflammation

Treatment of Chronic Experimental Autoimmune Encephalomyelitis with Epigallocatechin-3-Gallate and Glatiramer Acetate Alters Expression of Heme-Oxygenase-1

(2015) Antonia Janssen et al.   PLoS One

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models

(2014) Cornelia Schuh et al.   ACTA NEUROPATHOLOGICA

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

(2014) Rajkumar Noubade et al.   NATURE

Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo

(2014) Michael O Breckwoldt et al.   NATURE MEDICINE

Separating NADH and NADPH fluorescence in live cells and tissues using FLIM

(2014) Thomas S. Blacker et al.   Nature Communications

New Insights on NOX Enzymes in the Central Nervous System

(2013) Zeynab Nayernia et al.   ANTIOXIDANTS & REDOX SIGNALING

In Vivo Multiphoton NADH Fluorescence Reveals Depth-Dependent Keratinocyte Metabolism in Human Skin

(2013) Mihaela Balu et al.   BIOPHYSICAL JOURNAL

Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury

(2013) Sean J Cooney et al.   Journal of Neuroinflammation

Parallelized TCSPC for Dynamic Intravital Fluorescence Lifetime Imaging: Quantifying Neuronal Dysfunction in Neuroinflammation

(2013) Jan Leo Rinnenthal et al.   PLoS One

Epigallocatechin-3-gallate: a useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases?

(2013) Anja Mähler et al.   EPMA Journal

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

(2012) Jack van Horssen et al.   Journal of Neuroinflammation

Specific In Vivo Staining of Astrocytes in the Whole Brain after Intravenous Injection of Sulforhodamine Dyes

(2012) Florence Appaix et al.   PLoS One

Phasor Fluorescence Lifetime Microscopy of Free and Protein-Bound NADH Reveals Neural Stem Cell Differentiation Potential

(2012) Chiara Stringari et al.   PLoS One

Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH

(2012) Chiara Stringari et al.   Scientific Reports

Epigallocatechin-3-Gallate Ameliorates Experimental Autoimmune Encephalomyelitis by Altering Balance among CD4+ T-Cell Subsets

(2011) Junpeng Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

FLIM FRET Technology for Drug Discovery: Automated Multiwell-Plate High-Content Analysis, Multiplexed Readouts and Application in Situ

(2011) Sunil Kumar et al.   CHEMPHYSCHEM

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Distinct role of nitric oxide and peroxynitrite in mediating oligodendrocyte toxicity in culture and in experimental autoimmune encephalomyelitis

(2011) S. Li et al.   NEUROSCIENCE

Neuroprotective Effect of Combination Therapy of Glatiramer Acetate and Epigallocatechin-3-Gallate in Neuroinflammation

(2011) Katja Herges et al.   PLoS One

Expanding Two-Photon Intravital Microscopy to the Infrared by Means of Optical Parametric Oscillator

(2010) Josephine Herz et al.   BIOPHYSICAL JOURNAL

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis

(2010) Volker Siffrin et al.   IMMUNITY

NOX Enzymes in the Central Nervous System: From Signaling to Disease

(2009) Silvia Sorce et al.   ANTIOXIDANTS & REDOX SIGNALING

Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization

(2009) Volker Siffrin et al.   BRAIN

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme

(2008) Eui Seok Shin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

(2008) J. van Horssen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

(2008) C. Cheret et al.   JOURNAL OF NEUROSCIENCE

Effects of Epigallocatechin-3-gallate on lead-induced oxidative damage

(2008) Shu-Ting Yin et al.   TOXICOLOGY