Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling

Role of brain-derived neurotrophic factor and nerve growth factor in the regulation of Neuropeptide W in vitro and in vivo

(2017) Rikang Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Effects of Aged Garlic Extract on Cholinergic, Glutamatergic and GABAergic Systems with Regard to Cognitive Impairment in Aβ-Induced Rats

(2017) Piyaporn Thorajak et al.   Nutrients

Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways

(2017) Li Wang et al.   Scientific Reports

Neural mechanisms of information storage in visual short-term memory

(2016) John T. Serences   VISION RESEARCH

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

(2016) Gang Wang et al.   Oncotarget

Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress

(2015) Ying Xu et al.   NEUROBIOLOGY OF AGING

Type 4 phosphodiesterase enzyme inhibitor, rolipram rescues behavioral deficits in olfactory bulbectomy models of depression: Involvement of hypothalamic–pituitary–adrenal axis, cAMP signaling aspects and antioxidant defense system

(2015) Ankur Jindal et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Cyclic GMP–mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice

(2015) Lindsay M. Lueptow et al.   PSYCHOPHARMACOLOGY

The Roles of Phosphodiesterase 2 in the Central Nervous and Peripheral Systems

(2014) Chong Zhang et al.   CURRENT PHARMACEUTICAL DESIGN

Phosphodiesterase Inhibitors as a Target for Cognition Enhancement in Aging and Alzheimer’s Disease: A Translational Overview

(2014) P.R.A. Heckman et al.   CURRENT PHARMACEUTICAL DESIGN

Adrenocortical Status Predicts the Degree of Age-Related Deficits in Prefrontal Structural Plasticity and Working Memory

(2014) R. M. Anderson et al.   JOURNAL OF NEUROSCIENCE

Antidepressant-like effects of the phosphodiesterase-4 inhibitor etazolate and phosphodiesterase-5 inhibitor sildenafil via cyclic AMP or cyclic GMP signaling in mice

(2014) Chuang Wang et al.   METABOLIC BRAIN DISEASE

PDE4 as a target for cognition enhancement

(2013) Wito Richter et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Corticotropin releasing factor in neuroplasticity

(2013) Limor Regev et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway

(2012) Ying Xu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Central CRF system perturbation in an Alzheimer's disease knockin mouse model

(2012) Qinxi Guo et al.   NEUROBIOLOGY OF AGING

Deregulation of hypothalamic-pituitary-adrenal axis functions in an Alzheimer's disease rat model

(2012) Anthony Brureau et al.   NEUROBIOLOGY OF AGING

Are BDNF and glucocorticoid activities calibrated?

(2012) F. Jeanneteau et al.   NEUROSCIENCE

Hippocampal-Prefrontal Connectivity Predicts Midfrontal Oscillations and Long-Term Memory Performance

(2011) Michael X. Cohen   CURRENT BIOLOGY

The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats

(2011) Chuang Wang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Involvement of the cholinergic system of CA1 on harmane-induced amnesia in the step-down passive avoidance test

(2011) Mohammad Nasehi et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons

(2011) Subbiah Pugazhenthi et al.   Molecular Neurodegeneration

A Novel Neurotrophic Drug for Cognitive Enhancement and Alzheimer's Disease

(2011) Qi Chen et al.   PLoS One

Antidepressants, but not antipsychotics, modulate GR function in human whole blood: An insight into molecular mechanisms

(2010) L.A. Carvalho et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25–35 or Aβ1–40 peptide in rats

(2010) Yu-Fang Cheng et al.   PSYCHOPHARMACOLOGY

Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress

(2009) Ying Xu et al.   NEUROPHARMACOLOGY

Corticosterone and related receptor expression are associated with increased β-amyloid plaques in isolated Tg2576 mice

(2008) H. Dong et al.   NEUROSCIENCE