标题
The IL-23/IL-17 pathway in inflammatory bowel disease
作者
关键词
-
出版物
Expert Review of Gastroenterology & Hepatology
Volume 6, Issue 2, Pages 223-237
出版商
Informa UK Limited
发表日期
2012-02-29
DOI
10.1586/egh.11.107
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- An Evidence-Based Systematic Review on Medical Therapies for Inflammatory Bowel Disease
- (2011) Nicholas J Talley et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Analysis of IL2/IL21 Gene Variants in Cholestatic Liver Diseases Reveals an Association with Primary Sclerosing Cholangitis
- (2011) Johannes Stallhofer et al. DIGESTION
- IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease
- (2011) Alessandra Geremia et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
- (2011) Carl A Anderson et al. NATURE GENETICS
- Identification of an innate T helper type 17 response to intestinal bacterial pathogens
- (2011) Kaoru Geddes et al. NATURE MEDICINE
- The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans
- (2011) Paola Di Meglio et al. PLoS One
- Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q
- (2011) Svetlana Pidasheva et al. PLoS One
- Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses
- (2011) R. Sarin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disease Activity, ANCA and IL23R Genotype Status Determine Early Response to Infliximab in Patients With Ulcerative Colitis
- (2010) Matthias Jürgens et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- The IL-17 pathway as a major therapeutic target in autoimmune diseases
- (2010) Yan Hu et al. Annals of the New York Academy of Sciences
- Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells
- (2010) M. Dusseaux et al. BLOOD
- Interleukin-17 and its expanding biological functions
- (2010) Sheng Xu et al. Cellular & Molecular Immunology
- Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)
- (2010) M. NIESSNER et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Tumor Necrosis Factor-α Monoclonal Antibodies in the Treatment of Inflammatory Bowel Disease: Clinical Practice Pharmacology
- (2010) Thomas W. Lee et al. GASTROENTEROLOGY CLINICS OF NORTH AMERICA
- Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells
- (2010) Philip P. Ahern et al. IMMUNITY
- Regulation of Cytokine Secretion in Human CD127+ LTi-like Innate Lymphoid Cells by Toll-like Receptor 2
- (2010) Natasha K. Crellin et al. IMMUNITY
- CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut
- (2010) Gregory F. Sonnenberg et al. IMMUNITY
- Bacteria, mucosal-associated invariant T cells and MR1
- (2010) Wei-Jen Chua et al. IMMUNOLOGY AND CELL BIOLOGY
- Human NKp44+IL-22+cells and LTi-like cells constitute a stable RORC+lineage distinct from conventional natural killer cells
- (2010) Natasha K. Crellin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-7 and IL-15 independently program the differentiation of intestinal CD3−NKp46+cell subsets from Id2-dependent precursors
- (2010) Naoko Satoh-Takayama et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium
- (2010) A. J. Hueber et al. JOURNAL OF IMMUNOLOGY
- Cytokine Requirements for the Differentiation and Expansion of IL-17A- and IL-22-Producing Human V 2V 2 T Cells
- (2010) K. J. Ness-Schwickerath et al. JOURNAL OF IMMUNOLOGY
- Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
- (2010) Sofia Buonocore et al. NATURE
- Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
- (2010) Daniel R. Neill et al. NATURE
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
- (2010) Kamran Ghoreschi et al. NATURE
- Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
- (2010) Andre Franke et al. NATURE GENETICS
- Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties
- (2010) E. Billerbeck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease
- (2009) Jürgen Glas et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Relationship of C-Reactive Protein With Clinical Response After Therapy With Ustekinumab in Crohn's Disease
- (2009) Gary P Toedter et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- IL-17 and Th17 Cells
- (2009) Thomas Korn et al. Annual Review of Immunology
- Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis
- (2009) Yoshinaga Ito et al. ARTHRITIS AND RHEUMATISM
- Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses
- (2009) Harumichi Ishigame et al. IMMUNITY
- Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling
- (2009) Yeonseok Chung et al. IMMUNITY
- Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals
- (2009) Bruno Martin et al. IMMUNITY
- Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity
- (2009) Caroline E. Sutton et al. IMMUNITY
- IL-17 produced by neutrophils regulates IFN-γ–mediated neutrophil migration in mouse kidney ischemia-reperfusion injury
- (2009) Li Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation
- (2009) Melanie A. Kleinschek et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: IL-7 Regulates the Peripheral Pool of Adult ROR + Lymphoid Tissue Inducer Cells
- (2009) S. Schmutz et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: IL-23 Receptor GFP Reporter Mice Reveal Distinct Populations of IL-17-Producing Cells
- (2009) Amit Awasthi et al. JOURNAL OF IMMUNOLOGY
- IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-γ are not
- (2009) Kerstin Wolk et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
- (2009) Kazuyo Moro et al. NATURE
- The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
- (2009) Mandy J McGeachy et al. NATURE IMMUNOLOGY
- Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells
- (2009) Sara Trifari et al. NATURE IMMUNOLOGY
- Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
- (2009) Thomas Duhen et al. NATURE IMMUNOLOGY
- Inflammatory Bowel Disease
- (2009) Clara Abraham et al. NEW ENGLAND JOURNAL OF MEDICINE
- Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population
- (2009) Bin Chen et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Development of Secondary Lymphoid Organs
- (2008) Troy D. Randall et al. Annual Review of Immunology
- A Randomized Trial of Ustekinumab, a Human Interleukin-12/23 Monoclonal Antibody, in Patients With Moderate-to-Severe Crohn's Disease
- (2008) William J. Sandborn et al. GASTROENTEROLOGY
- Regulation of Gut Inflammation and Th17 Cell Response by Interleukin-21
- (2008) Daniele Fina et al. GASTROENTEROLOGY
- RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F
- (2008) Moritz Leppkes et al. GASTROENTEROLOGY
- IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
- (2008) T Kobayashi et al. GUT
- The role of the novel Th17 cytokine IL-26 in intestinal inflammation
- (2008) J Dambacher et al. GUT
- CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation
- (2008) John W. Northfield et al. HEPATOLOGY
- Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease
- (2008) Lauren A. Zenewicz et al. IMMUNITY
- Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis
- (2008) Ana Izcue et al. IMMUNITY
- T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
- (2008) Xuexian O. Yang et al. IMMUNITY
- IL-23/IL-17 immunity as a hallmark of Crohnʼs disease
- (2008) Veera Hölttä et al. INFLAMMATORY BOWEL DISEASES
- Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22
- (2008) Hiroaki Takatori et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulation of inflammatory responses by IL-17F
- (2008) Xuexian O. Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Human interleukin 17–producing cells originate from a CD161+CD4+T cell precursor
- (2008) Lorenzo Cosmi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- In vivo equilibrium of proinflammatory IL-17+and regulatory IL-10+Foxp3+RORγt+T cells
- (2008) Matthias Lochner et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
- (2008) Marina Cella et al. NATURE
- The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
- (2008) Marc Veldhoen et al. NATURE
- IL-21 and TGF-β are required for differentiation of human TH17 cells
- (2008) Li Yang et al. NATURE
- Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
- (2008) Andre Franke et al. NATURE GENETICS
- Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
- (2008) Sheila A Fisher et al. NATURE GENETICS
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells
- (2008) Fuping Zhang et al. NATURE IMMUNOLOGY
- Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells
- (2008) Tom Cupedo et al. NATURE IMMUNOLOGY
- The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
- (2008) Aurelie T Bauquet et al. NATURE IMMUNOLOGY
- A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
- (2008) Elisabetta Volpe et al. NATURE IMMUNOLOGY
- The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
- (2008) Nicolas Manel et al. NATURE IMMUNOLOGY
- IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
- (2008) Shean J Aujla et al. NATURE MEDICINE
- Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
- (2008) Yan Zheng et al. NATURE MEDICINE
- IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
- (2008) M. Huber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells
- (2008) A. Kimura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity
- (2007) Rosanne Spolski et al. Annual Review of Immunology
- Linking genetic susceptibility to Crohnʼs disease with Th17 cell function: IL-22 serum levels are increased in Crohnʼs disease and correlate with disease activity and IL23R genotype status
- (2007) Silke Schmechel et al. INFLAMMATORY BOWEL DISEASES
- Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active Crohnʼs disease and analysis of the IL17F p.His161Arg polymorphism in IBD
- (2007) Julia Seiderer et al. INFLAMMATORY BOWEL DISEASES
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