Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance

Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in mice

(2015) Marion Peyrou et al.   JOURNAL OF HEPATOLOGY

The brain and brown fat

(2014) Cristina Contreras et al.   ANNALS OF MEDICINE

RETRACTED: Grizzly Bears Exhibit Augmented Insulin Sensitivity while Obese Prior to a Reversible Insulin Resistance during Hibernation

(2014) O. Lynne Nelson et al.   Cell Metabolism

A Smooth Muscle-Like Origin for Beige Adipocytes

(2014) Jonathan Z. Long et al.   Cell Metabolism

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

(2014) Paul Lee et al.   Cell Metabolism

Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans

(2014) M. Chondronikola et al.   DIABETES

Temperature-Acclimated Brown Adipose Tissue Modulates Insulin Sensitivity in Humans

(2014) Paul Lee et al.   DIABETES

Does exposure to hyperglycaemiain uteroincrease the risk of obesity and diabetes in the offspring? A critical reappraisal

(2014) L. E. Donovan et al.   DIABETIC MEDICINE

From cytokine to myokine: the emerging role of interleukin-6 in metabolic regulation

(2014) Martin Pal et al.   IMMUNOLOGY AND CELL BIOLOGY

Increased Brown Adipose Tissue Oxidative Capacity in Cold-Acclimated Humans

(2014) Denis P. Blondin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Browning of white fat: does irisin play a role in humans?

(2014) Manuela Elsen et al.   JOURNAL OF ENDOCRINOLOGY

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation

(2014) Emilio P. Mottillo et al.   JOURNAL OF LIPID RESEARCH

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes

(2014) S. Ussar et al.   Science Translational Medicine

FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases

(2014) Nobuyuki Itoh   Frontiers in Endocrinology

BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells

(2013) Manuela Elsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Nutritional manipulations in the perinatal period program adipose tissue in offspring

(2013) Marie-Amélie Lukaszewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Bone morphogenic proteins signaling in adipogenesis and energy homeostasis

(2013) Salvatore Modica et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma

(2013) Andrea Frontini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Brown Adipose Tissue Thermogenesis

(2013) Ross A. Mund et al.   Cardiology in Review

A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

(2013) Naja Zenius Jespersen et al.   Cell Metabolism

Brown Adipose Tissue: Research Milestones of a Potential Player in Human Energy Balance and Obesity

(2013) B. Zafrir   HORMONE AND METABOLIC RESEARCH

Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans

(2013) M Matsushita et al.   INTERNATIONAL JOURNAL OF OBESITY

Recruited brown adipose tissue as an antiobesity agent in humans

(2013) Takeshi Yoneshiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Nebivolol induces, via β3 adrenergic receptor, lipolysis, uncoupling protein 1, and reduction of lipid droplet size in human adipocytes

(2013) Marica Bordicchia et al.   JOURNAL OF HYPERTENSION

Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat

(2013) Tim J. Schulz et al.   NATURE

Brown and beige fat: development, function and therapeutic potential

(2013) Matthew Harms et al.   NATURE MEDICINE

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

(2013) Angie L Bookout et al.   NATURE MEDICINE

Understanding the brown adipocyte as a contributor to energy homeostasis

(2013) Kanta Chechi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Differences in the metabolic status of healthy adults with and without active brown adipose tissue

(2013) Qiongyue Zhang et al.   WIENER KLINISCHE WOCHENSCHRIFT

Regulation of glucose homoeostasis by brown adipose tissue

(2013) Vivian Peirce et al.   Lancet Diabetes & Endocrinology

An essential role for Tbx15 in the differentiation of brown and “brite” but not white adipocytes

(2012) Valentina Gburcik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones

(2012) Paul A. Dutchak et al.   CELL

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

(2012) Ana Ortega-Molina et al.   Cell Metabolism

Adipose tissue and fetal programming

(2012) M. E. Symonds et al.   DIABETOLOGIA

Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high-fat-diet-induced obesity

(2012) Julien Auffret et al.   FASEB JOURNAL

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Mild Cold Exposure Modulates Fibroblast Growth Factor 21 (FGF21) Diurnal Rhythm in Humans: Relationship between FGF21 Levels, Lipolysis, and Cold-Induced Thermogenesis

(2012) Paul Lee et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

(2012) Kristin I. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

The hypothalamus–adipose axis is a key target of developmental programming by maternal nutritional manipulation

(2012) Christophe Breton   JOURNAL OF ENDOCRINOLOGY

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity

(2012) Aparna Pal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exercise as a new physiological stimulus for brown adipose tissue activity

(2012) R. De Matteis et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

The adipose organ: white-brown adipocyte plasticity and metabolic inflammation

(2012) A. Smorlesi et al.   Obesity Reviews

Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin

(2011) Janne Orava et al.   Cell Metabolism

Renaissance of Brown Adipose Tissue

(2011) D. Tews et al.   Hormone Research in Paediatrics

Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat

(2010) Elayne Hondares et al.   Cell Metabolism

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Perinatal environment and its influences on metabolic programming of offspring

(2010) Kellie L.K. Tamashiro et al.   PHYSIOLOGY & BEHAVIOR

Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat

(2010) T. J. Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beige Can Be Slimming

(2010) J. Ishibashi et al.   SCIENCE

The Lou/C rat: a model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue

(2009) Christelle Veyrat-Durebex et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Thyroid Hormone Effects on Whole-Body Energy Homeostasis and Tissue-Specific Fatty Acid Uptakein Vivo

(2009) Lars P. Klieverik et al.   ENDOCRINOLOGY

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thyroid Hormone Induced Brown Adipose Tissue and Amelioration of Diabetes in a Patient with Extreme Insulin Resistance

(2009) Monica C. Skarulis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY

Offspring from mothers fed a ‘junk food’ diet in pregnancy and lactation exhibit exacerbated adiposity that is more pronounced in females

(2008) S. A. Bayol et al.   JOURNAL OF PHYSIOLOGY-LONDON

Adipose Fibroblast Growth Factor 21 Is Up-Regulated by Peroxisome Proliferator-Activated Receptor   and Altered Metabolic States

(2008) E. S. Muise et al.   MOLECULAR PHARMACOLOGY

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance

(2007) Anne-Maj Samuelsson et al.   HYPERTENSION