The brain and brown fat

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

(2014) Paul Lee et al.   Cell Metabolism

Aging: It’s SIRTainly Possible to Restore Mitochondrial Dysfunction

(2014) Brooke E. Christian et al.   CURRENT BIOLOGY

Hypothalamic mTOR: The Rookie Energy Sensor

(2014) P. Martínez de Morentin et al.   CURRENT MOLECULAR MEDICINE

Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice

(2014) Liping Qiao et al.   DIABETOLOGIA

Nicotine Improves Obesity and Hepatic Steatosis and ER Stress in Diet-Induced Obese Male Rats

(2014) Patricia Seoane-Collazo et al.   ENDOCRINOLOGY

An endocrine role for brown adipose tissue?

(2013) Joan Villarroya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

FABP3 and brown adipocyte-characteristic mitochondrial fatty acid oxidation enzymes are induced in beige cells in a different pathway from UCP1

(2013) Yuki Nakamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

UCP1 mRNA does not produce heat

(2013) Jan Nedergaard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Beyond the Sympathetic Tone: The New Brown Fat Activators

(2013) Francesc Villarroya et al.   Cell Metabolism

Cold Exposure Promotes Atherosclerotic Plaque Growth and Instability via UCP1-Dependent Lipolysis

(2013) Mei Dong et al.   Cell Metabolism

Arcuate NPY Controls Sympathetic Output and BAT Function via a Relay of Tyrosine Hydroxylase Neurons in the PVN

(2013) Yan-Chuan Shi et al.   Cell Metabolism

A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

(2013) Naja Zenius Jespersen et al.   Cell Metabolism

Adiponectin Regulates Bone Mass via Opposite Central and Peripheral Mechanisms through FoxO1

(2013) Daisuke Kajimura et al.   Cell Metabolism

When BAT is lacking, WAT steps up

(2013) Andrew Whittle et al.   CELL RESEARCH

Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

(2013) Y. Zhang et al.   DIABETES

Amylin Acts in the Central Nervous System to Increase Sympathetic Nerve Activity

(2013) Caroline Fernandes-Santos et al.   ENDOCRINOLOGY

Firing Up Brown Fat with Brain Amylin

(2013) Miguel López et al.   ENDOCRINOLOGY

Orexin Restores Aging-Related Brown Adipose Tissue Dysfunction in Male Mice

(2013) Dyan Sellayah et al.   ENDOCRINOLOGY

Hypothalamic plasticity of neuropeptide Y is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation

(2013) Catharina E.E.M. Van der Zee   EUROPEAN JOURNAL OF PHARMACOLOGY

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

Functional thermogenic beige adipogenesis is inducible in human neck fat

(2013) P Lee et al.   INTERNATIONAL JOURNAL OF OBESITY

Conditional viral tracing reveals that steroidogenic factor 1-positive neurons of the dorsomedial subdivision of the ventromedial hypothalamus project to autonomic centers of the hypothalamus and hindbrain

(2013) Daniel Lindberg et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Adipogenesis: new insights into brown adipose tissue differentiation

(2013) Stefania Carobbio et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

 2 Adrenergic Receptor-Mediated Inhibition of Thermogenesis

(2013) C. J. Madden et al.   JOURNAL OF NEUROSCIENCE

Leptin Stimulates Neuropeptide Y and Cocaine Amphetamine-Regulated Transcript Coexpressing Neuronal Activity in the Dorsomedial Hypothalamus in Diet-Induced Obese Mice

(2013) S. J. Lee et al.   JOURNAL OF NEUROSCIENCE

Are skeletal muscleFNDC5gene expression and irisin release regulated by exercise and related to health?

(2013) Satu Pekkala et al.   JOURNAL OF PHYSIOLOGY-LONDON

White to brite adipocyte transition and back again

(2013) Youn-Kyoung Lee et al.   NATURE CELL BIOLOGY

Evidence for two types of brown adipose tissue in humans

(2013) Martin E Lidell et al.   NATURE MEDICINE

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

(2013) Angie L Bookout et al.   NATURE MEDICINE

Emerging combinatorial hormone therapies for the treatment of obesity and T2DM

(2013) Sharon A. Sadry et al.   Nature Reviews Endocrinology

Involvement of Hypothalamic AMP-Activated Protein Kinase in Leptin-Induced Sympathetic Nerve Activation

(2013) Mamoru Tanida et al.   PLoS One

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

Evidence against a Beneficial Effect of Irisin in Humans

(2013) Silja Raschke et al.   PLoS One

Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPAR 

(2013) F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy balance regulation by thyroid hormones at central level

(2013) Miguel López et al.   TRENDS IN MOLECULAR MEDICINE

Pharmacological strategies for targeting BAT thermogenesis

(2013) Andrew Whittle et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Irisin, Two Years Later

(2013) Marta G. Novelle et al.   International Journal of Endocrinology

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

(2013) Irina G. Shabalina et al.   Cell Reports

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

(2013) Ulrike Liisberg Aune et al.   Jove-Journal of Visualized Experiments

Brown adipose tissue thermogenesis in the resistance to and reversal of obesity

(2013) Sarah H Lockie et al.   Adipocyte

Anterograde transneuronal viral tract tracing reveals central sensory circuits from brown fat and sensory denervation alters its thermogenic responses

(2012) Cheryl H. Vaughan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hyperthyroidism differentially regulates neuropeptide S system in the rat brain

(2012) Carmen R. González et al.   BRAIN RESEARCH

GABAergic RIP-Cre Neurons in the Arcuate Nucleus Selectively Regulate Energy Expenditure

(2012) Dong Kong et al.   CELL

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis

(2012) Li Ye et al.   CELL

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

(2012) Haruya Ohno et al.   Cell Metabolism

2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism

(2012) Kwang-Mook Jung et al.   Cell Metabolism

Circulating Fibroblast Growth Factors as Metabolic Regulators—A Critical Appraisal

(2012) Bo Angelin et al.   Cell Metabolism

Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

(2012) Ana Ortega-Molina et al.   Cell Metabolism

Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant

(2012) S. C. Gunawardana et al.   DIABETES

A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization

(2012) S. Virtue et al.   DIABETES

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling

(2012) S. H. Lockie et al.   DIABETES

Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase

(2012) P. B. Martinez de Morentin et al.   DIABETES

Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice

(2012) Pierre Cardinal et al.   ENDOCRINOLOGY

Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway

(2012) Kristy L. Townsend et al.   FASEB JOURNAL

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Nesfatin-1 exerts long-term effect on food intake and body temperature

(2012) K Könczöl et al.   INTERNATIONAL JOURNAL OF OBESITY

Mechanisms of thyroid hormone action

(2012) Gregory A. Brent   JOURNAL OF CLINICAL INVESTIGATION

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

(2012) Marica Bordicchia et al.   JOURNAL OF CLINICAL INVESTIGATION

Thyroid hormone and the central control of homeostasis

(2012) Amy Warner et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Central Resistin Enhances Renal Sympathetic Nerve Activity via Phosphatidylinositol 3-Kinase but Reduces the Activity to Brown Adipose Tissue via Extracellular Signal-Regulated Kinase 1/2

(2012) S. Kosari et al.   JOURNAL OF NEUROENDOCRINOLOGY

Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism

(2012) Luis Varela et al.   JOURNAL OF PATHOLOGY

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

(2012) Florian W Kiefer et al.   NATURE MEDICINE

Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling

(2012) Hu Huang et al.   NATURE NEUROSCIENCE

Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

(2012) Ruben Nogueiras et al.   PHYSIOLOGICAL REVIEWS

Lipocalin Prostaglandin D Synthase and PPARγ2 Coordinate to Regulate Carbohydrate and Lipid Metabolism In Vivo

(2012) Sam Virtue et al.   PLoS One

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells

(2012) Louis Z. Sharp et al.   PLoS One

An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis

(2012) Shaun F. Morrison et al.   Adipocyte

Orexin receptor-1 mediates brown fat developmental differentiation

(2012) Dyan Sellayah et al.   Adipocyte

Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues

(2011) Ligen Lin et al.   AGING CELL

Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues

(2011) Tomas B. Waldén et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Implications of nonshivering thermogenesis for energy balance regulation in humans

(2011) Wouter D. van Marken Lichtenbelt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Knockdown of NPY Expression in the Dorsomedial Hypothalamus Promotes Development of Brown Adipocytes and Prevents Diet-Induced Obesity

(2011) Pei-Ting Chao et al.   Cell Metabolism

Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin

(2011) Janne Orava et al.   Cell Metabolism

Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

(2011) Yong Xu et al.   Cell Metabolism

Orexin Is Required for Brown Adipose Tissue Development, Differentiation, and Function

(2011) Dyan Sellayah et al.   Cell Metabolism

Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation

(2011) Shannon M. Harlan et al.   CIRCULATION RESEARCH

Neuronal Receptor Activity-Modifying Protein 1 Promotes Energy Expenditure in Mice

(2011) Z. Zhang et al.   DIABETES

Disruption of Thyroid Hormone Activation in Type 2 Deiodinase Knockout Mice Causes Obesity With Glucose Intolerance and Liver Steatosis Only at Thermoneutrality

(2011) M. Castillo et al.   DIABETES

Adiponectin Inhibits Lipolysis in Mouse Adipocytes

(2011) L. Qiao et al.   DIABETES

The Bile Acid Membrane Receptor TGR5: A Valuable Metabolic Target

(2011) Thijs W.H. Pols et al.   DIGESTIVE DISEASES

The physiological implication of novel proteins in systemic osmoregulation

(2011) Anne P. Sinke et al.   FASEB JOURNAL

Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

(2011) Elayne Hondares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous BDNF regulates inhibitory synaptic transmission in the ventromedial nucleus of the hypothalamus

(2011) Young-Hwan Jo   JOURNAL OF NEUROPHYSIOLOGY

Leptin Action in the Dorsomedial Hypothalamus Increases Sympathetic Tone to Brown Adipose Tissue in Spite of Systemic Leptin Resistance

(2011) P. J. Enriori et al.   JOURNAL OF NEUROSCIENCE

Leptin-Receptor-Expressing Neurons in the Dorsomedial Hypothalamus and Median Preoptic Area Regulate Sympathetic Brown Adipose Tissue Circuits

(2011) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

An Orexinergic Projection from Perifornical Hypothalamus to Raphe Pallidus Increases Rat Brown Adipose Tissue Thermogenesis

(2011) D. Tupone et al.   JOURNAL OF NEUROSCIENCE

CrbpI Modulates Glucose Homeostasis and Pancreas 9-cis-Retinoic Acid Concentrations

(2011) M. A. Kane et al.   MOLECULAR AND CELLULAR BIOLOGY

Brown adipose tissue activity controls triglyceride clearance

(2011) Alexander Bartelt et al.   NATURE MEDICINE

Hypothalamic Control of Lipid Metabolism: Focus on Leptin, Ghrelin and Melanocortins

(2011) Carlos Diéguez et al.   NEUROENDOCRINOLOGY

Role of the hypothalamus in the neuroendocrine regulation of body weight and composition during energy deficit

(2011) A. Sainsbury et al.   Obesity Reviews

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

(2011) K. W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypothalamic AMP-activated protein kinase as a mediator of whole body energy balance

(2011) Pablo Blanco Martínez de Morentin et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Using brown adipose tissue to treat obesity – the central issue

(2011) Andrew J. Whittle et al.   TRENDS IN MOLECULAR MEDICINE

Brown fat as a therapy for obesity and diabetes

(2011) Aaron M Cypess et al.   Current Opinion in Endocrinology Diabetes and Obesity

Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice

(2010) Carola W. Meyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

PPARα does not suppress muscle-associated gene expression in brown adipocytes but does influence expression of factors that fingerprint the brown adipocyte

(2010) Tomas B. Waldén et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat

(2010) Elayne Hondares et al.   Cell Metabolism

Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats

(2010) D. A. Sarruf et al.   DIABETES

Molecular Aspects of Thyroid Hormone Actions

(2010) Sheue-Yann Cheng et al.   ENDOCRINE REVIEWS

The T3Receptor β1 Isoform Regulates UCP1 and D2 Deiodinase in Rat Brown Adipocytes

(2010) Raquel Martinez de Mena et al.   ENDOCRINOLOGY

Transcriptional control of brown adipocyte development and thermogenesis

(2010) P Seale   INTERNATIONAL JOURNAL OF OBESITY

Sympathetic and sensory innervation of brown adipose tissue

(2010) T J Bartness et al.   INTERNATIONAL JOURNAL OF OBESITY

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Orexin neurons are indispensable for stress-induced thermogenesis in mice

(2010) Wei Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Globular adiponectin regulates energy homeostasis through AMP-activated protein kinase–acetyl-CoA carboxylase (AMPK/ACC) pathway in the hypothalamus

(2010) Jun-Ping Wen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

(2010) Miguel López et al.   NATURE MEDICINE

Transplantation of adipose tissue and stem cells: role in metabolism and disease

(2010) Thien T. Tran et al.   Nature Reviews Endocrinology

Central amylin acts as an adiposity signal to control body weight and energy expenditure

(2010) Peter Y. Wielinga et al.   PHYSIOLOGY & BEHAVIOR

UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity

(2010) Lise Madsen et al.   PLoS One

Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat

(2010) T. J. Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beige Can Be Slimming

(2010) J. Ishibashi et al.   SCIENCE

Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes

(2010) A. Vegiopoulos et al.   SCIENCE

Orexins (hypocretins) actions on the GHRH/somatostatin-GH axis

(2009) M. López et al.   Acta Physiologica

Leptin at 14 y of age: an ongoing story

(2009) Jeffrey M Friedman   AMERICAN JOURNAL OF CLINICAL NUTRITION

Neurons in the paraventricular nucleus of the hypothalamus inhibit sympathetic outflow to brown adipose tissue

(2009) C. J. Madden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

CNS-targets in control of energy and glucose homeostasis

(2009) André Kleinridders et al.   CURRENT OPINION IN PHARMACOLOGY

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Hypothalamic and Hindbrain Melanocortin Receptors Contribute to the Feeding, Thermogenic, and Cardiovascular Action of Melanocortins

(2009) Karolina P. Skibicka et al.   ENDOCRINOLOGY

Expression of Uncoupling Protein 1 in Mouse Brown Adipose Tissue Is Thyroid Hormone Receptor-β Isoform Specific and Required for Adaptive Thermogenesis

(2009) Miriam O. Ribeiro et al.   ENDOCRINOLOGY

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue

(2009) Maria Cristina Zingaretti et al.   FASEB JOURNAL

Cross-talk between orexins (hypocretins) and the neuroendocrine axes (hypothalamic–pituitary axes)

(2009) Miguel López et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Transcriptional control of brown adipocyte development and physiological function--of mice and men

(2009) P. Seale et al.   GENES & DEVELOPMENT

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thyroid Hormone Induced Brown Adipose Tissue and Amelioration of Diabetes in a Patient with Extreme Insulin Resistance

(2009) Monica C. Skarulis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues

(2009) B. Xue et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of transient receptor potential channels in kidney disease

(2009) Titia E. Woudenberg-Vrenken et al.   Nature Reviews Nephrology

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enhanced Weight Loss With Pramlintide/Metreleptin: An Integrated Neurohormonal Approach to Obesity Pharmacotherapy

(2009) Eric Ravussin et al.   Obesity

PRDM16: the interconvertible adipo-myocyte switch

(2009) Gema Frühbeck et al.   TRENDS IN CELL BIOLOGY

BAT: a new target for human obesity?

(2009) Gema Frühbeck et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: neuroanatomical and functional evidence

(2008) C. Kay Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Regulation of Food Intake Through Hypothalamic Signaling Networks Involving mTOR

(2008) Stephen C Woods et al.   Annual Review of Nutrition

PGC-1α induces dynamic protein interactions on the ERRα gene multi-hormone response element nucleosome in kidney cells

(2008) Liangli Wang et al.   BIOCHEMICAL JOURNAL

Blockade of prostaglandin E2-induced thermogenesis by unilateral microinjection of GABAA receptor antagonist into the preoptic area

(2008) Toshimasa Osaka   BRAIN RESEARCH

The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man

(2008) Cecilia Gälman et al.   Cell Metabolism

Before They Were Fat: Adipocyte Progenitors

(2008) Kye Won Park et al.   Cell Metabolism

Hypothalamic Fatty Acid Metabolism Mediates the Orexigenic Action of Ghrelin

(2008) Miguel López et al.   Cell Metabolism

Sustained Weight Loss Following 12-Month Pramlintide Treatment as an Adjunct to Lifestyle Intervention in Obesity

(2008) S. R. Smith et al.   DIABETES CARE

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling1

(2008) Balázs Gereben et al.   ENDOCRINE REVIEWS

Central Resistin Regulates Hypothalamic and Peripheral Lipid Metabolism in a Nutritional-Dependent Fashion

(2008) María J. Vázquez et al.   ENDOCRINOLOGY

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

(2008) S. Kajimura et al.   GENES & DEVELOPMENT

Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons

(2008) E Guillod-Maximin et al.   JOURNAL OF ENDOCRINOLOGY

Preoptic mechanism for cold-defensive responses to skin cooling

(2008) Kazuhiro Nakamura et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Functional Interaction between RIP140 and PGC-1  Regulates the Expression of the Lipid Droplet Protein CIDEA

(2008) M. Hallberg et al.   MOLECULAR AND CELLULAR BIOLOGY

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

(2008) Zane B. Andrews et al.   NATURE

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

Brain circuits regulating energy homeostasis

(2008) Alfonso Abizaid et al.   REGULATORY PEPTIDES

Thyroid Hormone as a Determinant of Energy Expenditure and the Basal Metabolic Rate

(2008) Brian Kim   THYROID

AMPK: a metabolic gauge regulating whole-body energy homeostasis

(2008) Ricardo Lage et al.   TRENDS IN MOLECULAR MEDICINE

The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance

(2007) Gijs H. Goossens   PHYSIOLOGY & BEHAVIOR