Detection of antibiotics synthetized in microfluidic picolitre-droplets by various actinobacteria

A droplet-chip/mass spectrometry approach to study organic synthesis at nanoliter scale

(2017) R. J. Beulig et al.   LAB ON A CHIP

Rare, high-affinity mouse anti-PD-1 antibodies that function in checkpoint blockade, discovered using microfluidics and molecular genomics

(2017) Adam S. Adler et al.   mAbs

Droplet-based microfluidic high-throughput screening of heterologous enzymes secreted by the yeast Yarrowia lipolytica

(2017) Thomas Beneyton et al.   Microbial Cell Factories

Actinomycetes: still a source of novel antibiotics

(2017) Olga Genilloud   NATURAL PRODUCT REPORTS

Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring

(2017) Klaus Eyer et al.   NATURE BIOTECHNOLOGY

Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity

(2017) Stanislav S. Terekhov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening

(2017) Andrew B. MacConnell et al.   ACS Combinatorial Science

hνSABR: Photochemical Dose–Response Bead Screening in Droplets

(2016) Alexander K. Price et al.   ANALYTICAL CHEMISTRY

Natural product discovery: past, present, and future

(2016) Leonard Katz et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Droplet microfluidics for microbiology: techniques, applications and challenges

(2016) Tomasz S. Kaminski et al.   LAB ON A CHIP

Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics

(2016) Nachiket Shembekar et al.   LAB ON A CHIP

Ultrahigh-throughput–directed enzyme evolution by absorbance-activated droplet sorting (AADS)

(2016) Fabrice Gielen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlling molecular transport in minimal emulsions

(2016) Philipp Gruner et al.   Nature Communications

Discovery in Droplets

(2015) Alexander K. Price et al.   ANALYTICAL CHEMISTRY

Digital Microfluidic Cell Culture

(2015) Alphonsus H.C. Ng et al.   Annual Review of Biomedical Engineering

Elicitation of secondary metabolism in actinomycetes

(2015) Usama Ramadan Abdelmohsen et al.   BIOTECHNOLOGY ADVANCES

The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation

(2015) David J. Collins et al.   LAB ON A CHIP

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics

(2015) Pierre-Yves Colin et al.   Nature Communications

Enhanced and homogeneous oxygen availability during incubation of microfluidic droplets

(2015) Lisa Mahler et al.   RSC Advances

Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates

(2015) Marla Trindade et al.   Frontiers in Microbiology

Current and future resources for functional metagenomics

(2015) Kathy N. Lam et al.   Frontiers in Microbiology

CotA laccase: high-throughput manipulation and analysis of recombinant enzyme libraries expressed in E. coli using droplet-based microfluidics

(2014) Thomas Beneyton et al.   ANALYST

Interfacing Microwells with Nanoliter Compartments: A Sampler Generating High-Resolution Concentration Gradients for Quantitative Biochemical Analyses in Droplets

(2014) Fabrice Gielen et al.   ANALYTICAL CHEMISTRY

New Tools for Comparing Microscopy Images: Quantitative Analysis of Cell Types in Bacillus subtilis

(2014) Jordi van Gestel et al.   JOURNAL OF BACTERIOLOGY

High-throughput platform for the discovery of elicitors of silent bacterial gene clusters

(2014) M. R. Seyedsayamdost   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A high-throughput screen for antibiotic drug discovery

(2013) Thomas C. Scanlon et al.   BIOTECHNOLOGY AND BIOENGINEERING

Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets

(2013) Emerson Zang et al.   LAB ON A CHIP

High-throughput screening for industrial enzyme production hosts by droplet microfluidics

(2013) Staffan L. Sjostrom et al.   LAB ON A CHIP

Single-cell analysis and sorting using droplet-based microfluidics

(2013) Linas Mazutis et al.   Nature Protocols

SINA: Accurate high-throughput multiple sequence alignment of ribosomal RNA genes

(2012) Elmar Pruesse et al.   BIOINFORMATICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Functional single-cell hybridoma screening using droplet-based microfluidics

(2012) B. E. Debs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PRODUCTION OF ANTIBIOTIC SUBSTANCES BY ACTINOMYCETES*†

(2010) Selman A. Waksman et al.   Annals of the New York Academy of Sciences

Approaches to Capturing and Designing Biologically Active Small Molecules Produced by Uncultured Microbes

(2010) Jörn Piel   Annual Review of Microbiology

An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries

(2010) Jenifer Clausell-Tormos et al.   LAB ON A CHIP

High-throughput injection with microfluidics using picoinjectors

(2010) A. R. Abate et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

(2009) Jean-Christophe Baret et al.   LAB ON A CHIP

Functional Cell-Based Assays in Microliter Volumes for Ultra-High Throughput Screening

(2008) Frank Wunder et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

The All-Species Living Tree project: A 16S rRNA-based phylogenetic tree of all sequenced type strains

(2008) Pablo Yarza et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY