Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway

Census and evaluation of p53 target genes

(2017) M Fischer   ONCOGENE

The human papillomavirus E7 oncoprotein as a regulator of transcription

(2017) William K. Songock et al.   VIRUS RESEARCH

p21 governs p53's repressive side

(2016) Martin Fischer   CELL CYCLE

RB1: a prototype tumor suppressor and an enigma

(2016) Nicholas J. Dyson   GENES & DEVELOPMENT

Keratin Isotypes Control Desmosome Stability and Dynamics through PKCα

(2016) Fanny Loschke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of WDHD1 in Human Papillomavirus-Mediated Oncogenesis Identified by Transcriptional Profiling of E7-Expressing Cells

(2016) Yunying Zhou et al.   JOURNAL OF VIROLOGY

Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

(2016) Denise Martinez-Zapien et al.   NATURE

Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks

(2016) Martin Fischer et al.   NUCLEIC ACIDS RESEARCH

Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters

(2016) Aimee H. Marceau et al.   Nature Communications

Timing of transcription during the cell cycle: Protein complexes binding to E2F, E2F/CLE, CDE/CHR, or CHR promoter elements define early and late cell cycle gene expression

(2016) Gerd A. Müller et al.   Oncotarget

Structural mechanisms of DREAM complex assembly and regulation

(2015) Keelan Z. Guiley et al.   GENES & DEVELOPMENT

Epidemiology of Human Papillomavirus–Positive Head and Neck Squamous Cell Carcinoma

(2015) Maura L. Gillison et al.   JOURNAL OF CLINICAL ONCOLOGY

The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genes

(2015) Martin Fischer et al.   NUCLEIC ACIDS RESEARCH

Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo

(2015) Ulrike Fischer et al.   Oncotarget

The transcription factor p53: Not a repressor, solely an activator

(2014) Martin Fischer et al.   CELL CYCLE

The CHR site: definition and genome-wide identification of a cell cycle transcriptional element

(2014) Gerd A. Müller et al.   NUCLEIC ACIDS RESEARCH

Cyclin D activates the Rb tumor suppressor by mono-phosphorylation

(2014) Anil M Narasimha et al.   eLife

Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein

(2013) Martin Fischer et al.   NUCLEIC ACIDS RESEARCH

A functional interaction of E7 with B-Myb-MuvB complex promotes acute cooperative transcriptional activation of both S- and M-phase genes. (129 c)

(2013) C L Pang et al.   ONCOGENE

p53 and Cell Cycle Dependent Transcription of kinesin family member 23 (KIF23) Is Controlled Via a CHR Promoter Element Bound by DREAM and MMB Complexes

(2013) Martin Fischer et al.   PLoS One

Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines

(2013) M. E. McLaughlin-Drubin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Control of Human Papillomavirus Infections and Related Diseases

(2013) F. Xavier Bosch et al.   VACCINE

p53 can repress transcription of cell cycle genes through a p21WAF1/CIP1-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements

(2012) Marianne Quaas et al.   CELL CYCLE

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

(2012) Orit Rozenblatt-Rosen et al.   NATURE

Identification of FAM111A as an SV40 Host Range Restriction and Adenovirus Helper Factor

(2012) Debrah A. Fine et al.   PLoS Pathogens

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

(2011) Assaf C. Bester et al.   CELL

Disruption of repressive p130-DREAM complexes by human papillomavirus 16 E6/E7 oncoproteins is required for cell-cycle progression in cervical cancer cells

(2011) N. Nor Rashid et al.   JOURNAL OF GENERAL VIROLOGY

The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes

(2011) Gerd A. Müller et al.   NUCLEIC ACIDS RESEARCH

Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growth

(2011) S Hauser et al.   ONCOGENE

Human Papillomavirus E7 Oncoprotein Overrides the Tumor Suppressor Activity of p21Cip1 in Cervical Carcinogenesis

(2009) M.-K. Shin et al.   CANCER RESEARCH

B-MYB Is Required for Recovery from the DNA Damage-Induced G2 Checkpoint in p53 Mutant Cells

(2009) M. Mannefeld et al.   CANCER RESEARCH

The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription

(2009) Gerd A. Müller et al.   FEBS Journal

Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site

(2008) Ralf D. Kirschner et al.   NUCLEIC ACIDS RESEARCH

The human papillomavirus E7 oncoprotein

(2008) Margaret E. McLaughlin-Drubin et al.   VIROLOGY