Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis

Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

(2016) Satoshi Tanaka et al.   HEPATOLOGY

Legionella pneumophilaS1P-lyase targets host sphingolipid metabolism and restrains autophagy

(2016) Monica Rolando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion

(2015) Yuxuan Miao et al.   CELL

Emerging themes in bacterial autophagy

(2015) Matthew T Sorbara et al.   CURRENT OPINION IN MICROBIOLOGY

Structured illumination microscopy and correlative microscopy to study autophagy

(2015) Laure-Anne Ligeon et al.   METHODS

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy

(2015) Yuchen Feng et al.   TRENDS IN CELL BIOLOGY

Escape of Actively Secreting Shigella flexneri from ATG8/LC3-Positive Vacuoles Formed during Cell-To-Cell Spread Is Facilitated by IcsB and VirA

(2015) François-Xavier Campbell-Valois et al.   mBio

Stimulation of autophagy suppresses the intracellular survival ofBurkholderia pseudomalleiin mammalian cell lines

(2014) Méabh Cullinane et al.   Autophagy

LC3-associated phagocytosis

(2014) Susana Romao et al.   Autophagy

Correlative light and electron microscopy imaging of autophagy in a zebrafish infection model

(2014) Rohola Hosseini et al.   Autophagy

Role of VAMP3 and VAMP7 in the commitment ofYersinia pseudotuberculosisto LC3-associated pathways involving single- or double-membrane vacuoles

(2014) Laure-Anne Ligeon et al.   Autophagy

Coxiella burnetii Type IV Secretion-Dependent Recruitment of Macrophage Autophagosomes

(2014) C. G. Winchell et al.   INFECTION AND IMMUNITY

Autophagy Induced by Calcium Phosphate Precipitates Targets Damaged Endosomes

(2014) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy in Antimicrobial Immunity

(2014) Ligia C. Gomes et al.   MOLECULAR CELL

Cargo recognition and trafficking in selective autophagy

(2014) Alexandra Stolz et al.   NATURE CELL BIOLOGY

Bacteria–autophagy interplay: a battle for survival

(2014) Ju Huang et al.   NATURE REVIEWS MICROBIOLOGY

Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5

(2014) M. Lucas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VipD is a Rab5-activated phospholipase A1 that protects Legionella pneumophila from endosomal fusion

(2014) A. H. Gaspar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live-Cell Imaging of Phosphoinositide Dynamics and Membrane Architecture during Legionella Infection

(2014) S. Weber et al.   mBio

A Screen of Coxiella burnetii Mutants Reveals Important Roles for Dot/Icm Effectors and Host Autophagy in Vacuole Biogenesis

(2014) Hayley J. Newton et al.   PLoS Pathogens

The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins

(2014) Andree Hubber et al.   PLoS Pathogens

Ubiquitination as an Efficient Molecular Strategy Employed in Salmonella Infection

(2014) Lakshmi A. Narayanan et al.   Frontiers in Immunology

Host and bacterial factors that regulate LC3 recruitment toListeria monocytogenesduring the early stages of macrophage infection

(2013) Grace Y. Lam et al.   Autophagy

Noncanonical autophagy: one small step for LC3, one giant leap for immunity

(2013) Payal Mehta et al.   CURRENT OPINION IN IMMUNOLOGY

Amphisomes: out of the autophagosome shadow?

(2013) Jana Sanchez-Wandelmer et al.   EMBO JOURNAL

Legionella oakridgensis ATCC 33761 genome sequence and phenotypic characterization reveals its replication capacity in amoebae

(2013) Elzbieta Brzuszkiewicz et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing

(2013) Susana Romao et al.   JOURNAL OF CELL BIOLOGY

Observation of autophagosome maturation in the interferon-γ-primed and lipopolysaccharide-activated macrophages using a tandem fluorescent tagged LC3

(2013) Eri Fujiwara et al.   JOURNAL OF IMMUNOLOGICAL METHODS

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Molecular mechanisms of selective autophagy

(2012) G M Fimia et al.   CELL DEATH AND DIFFERENTIATION

Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program

(2012) Ivan Tattoli et al.   Cell Host & Microbe

Beclin 1 Is Required for Starvation-Enhanced, but Not Rapamycin-Enhanced, LC3-Associated Phagocytosis of Burkholderia pseudomallei in RAW 264.7 Cells

(2012) Xuelei Li et al.   INFECTION AND IMMUNITY

Chlamydia trachomatis vacuole maturation in infected macrophages

(2012) He Song Sun et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase

(2012) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infections caused by nonpneumophila species of Legionella

(2012) Ivana Gobin et al.   REVIEWS IN MEDICAL MICROBIOLOGY

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

Autophagy proteins in macroendocytic engulfment

(2012) Oliver Florey et al.   TRENDS IN CELL BIOLOGY

VipD of Legionella pneumophila Targets Activated Rab5 and Rab22 to Interfere with Endosomal Trafficking in Macrophages

(2012) Bonsu Ku et al.   PLoS Pathogens

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

A role for diacylglycerol in antibacterial autophagy

(2011) Shahab Shahnazari et al.   Autophagy

The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway

(2011) Marija Cemma et al.   Autophagy

A Tecpr1-Dependent Selective Autophagy Pathway Targets Bacterial Pathogens

(2011) Michinaga Ogawa et al.   Cell Host & Microbe

Mycobacterium marinum induces a marked LC3 recruitment to its containing phagosome that depends on a functional ESX-1 secretion system

(2011) María Cecilia Lerena et al.   CELLULAR MICROBIOLOGY

TLR2 and RIP2 Pathways Mediate Autophagy ofListeria monocytogenesvia Extracellular Signal-regulated Kinase (ERK) Activation

(2011) Paras K. Anand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

(2011) Shun Kageyama et al.   MOLECULAR BIOLOGY OF THE CELL

China's academic autocracy must go

(2011) Nai-Zhuo Zhao   NATURE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

The Burkholderia pseudomallei Type III Secretion System and BopA Are Required for Evasion of LC3-Associated Phagocytosis

(2011) Lan Gong et al.   PLoS One

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virulence Properties of the Legionella Pneumophila Cell Envelope

(2011) Olga Shevchuk et al.   Frontiers in Microbiology

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

What Determines the Specificity and Outcomes of Ubiquitin Signaling?

(2010) Fumiyo Ikeda et al.   CELL

A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial Autophagy

(2010) Shahab Shahnazari et al.   Cell Host & Microbe

Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila

(2010) Sze Man Tung et al.   CELLULAR MICROBIOLOGY

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

A Method for Generation of Bone Marrow-Derived Macrophages from Cryopreserved Mouse Bone Marrow Cells

(2010) Fernanda M. Marim et al.   PLoS One

The many roles of NOX2 NADPH oxidase-derived ROS in immunity

(2010) Grace Y. Lam et al.   Seminars in Immunopathology

Legionella pneumophila Promotes Functional Interactions between Plasma Membrane Syntaxins and Sec22b

(2010) Kohei Arasaki et al.   TRAFFIC

Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease

(2010) Christel Cazalet et al.   PLoS Genetics

Listeria monocytogenesActA is a key player in evading autophagic recognition

(2009) Yuko Yoshikawa et al.   Autophagy

Autophagy induced by 2-deoxy-D-glucose suppresses intracellular multiplication ofLegionella pneumophilain A/J mouse macrophages

(2009) Fumiko Matsuda et al.   Autophagy

Galectin-3, a marker for vacuole lysis by invasive pathogens

(2009) Irit Paz et al.   CELLULAR MICROBIOLOGY

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of ubiquitin dynamics and suppression of DALIS formation by theLegionella pneumophilaDot/Icm system

(2008) Stanimir S. Ivanov et al.   CELLULAR MICROBIOLOGY

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species

(2008) C. Cazalet et al.   GENOME RESEARCH

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY

Legionella spp. and Legionnaires' disease

(2007) B.M.W. Diederen   JOURNAL OF INFECTION