Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits

PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation

(2016) Smitha Karunakaran et al.   NATURE NEUROSCIENCE

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks

(2015) Roberta Pennucci et al.   CEREBRAL CORTEX

Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems

(2015) Zhong L. Hua et al.   Neural Development

Early- and Late-Born Parvalbumin Basket Cell Subpopulations Exhibiting Distinct Regulation and Roles in Learning

(2015) Flavio Donato et al.   NEURON

Gamma Rhythms Link Prefrontal Interneuron Dysfunction with Cognitive Inflexibility in Dlx5/6+/− Mice

(2015) Kathleen K.A. Cho et al.   NEURON

Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 ofMecp2knockout mice

(2014) Gaston Calfa et al.   HIPPOCAMPUS

2-Amino-3-(phenylsulfanyl)norbornane-2-carboxylate: An Appealing Scaffold for the Design of Rac1–Tiam1 Protein–Protein Interaction Inhibitors

(2014) Alessandro Ruffoni et al.   JOURNAL OF MEDICINAL CHEMISTRY

Loss of hnRNP K Impairs Synaptic Plasticity in Hippocampal Neurons

(2014) A. Folci et al.   JOURNAL OF NEUROSCIENCE

Altered Distribution of Hippocampal Interneurons in the Murine Down Syndrome Model Ts65Dn

(2014) Samuel Hernández-González et al.   NEUROCHEMICAL RESEARCH

Roles of Rac1 and Rac3 GTPases during the development of cortical and hippocampal GABAergic interneurons

(2014) Ivan de Curtis   Frontiers in Cellular Neuroscience

Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders

(2013) Peter Penzes et al.   JOURNAL OF NEUROCHEMISTRY

Actin dynamics in growth cone motility and navigation

(2013) Timothy M. Gomez et al.   JOURNAL OF NEUROCHEMISTRY

Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning

(2013) Flavio Donato et al.   NATURE

GABAergic Interneurons Shape the Functional Maturation of the Cortex

(2013) Corentin Le Magueresse et al.   NEURON

Hippocampal development – Old and new findings

(2013) R. Khalaf-Nazzal et al.   NEUROSCIENCE

The RacGAP β2-Chimaerin Selectively Mediates Axonal Pruning in the Hippocampus

(2012) Martin M. Riccomagno et al.   CELL

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin

(2012) M. Rosario et al.   GENES & DEVELOPMENT

Alteration of Synaptic Network Dynamics by the Intellectual Disability Protein PAK3

(2012) A. Dubos et al.   JOURNAL OF NEUROSCIENCE

Leptin Counteracts the Hypoxia-Induced Inhibition of Spontaneously Firing Hippocampal Neurons: A Microelectrode Array Study

(2012) Daniela Gavello et al.   PLoS One

POSH Localizes Activated Rac1 to Control the Formation of Cytoplasmic Dilation of the Leading Process and Neuronal Migration

(2012) Tao Yang et al.   Cell Reports

Severe intellectual disability, omphalocele, hypospadia and high blood pressure associated to a deletion at 2q22.1q22.3: case report

(2012) Milene Mulatinho et al.   Molecular Cytogenetics

GABA through the Ages: Regulation of Cortical Function and Plasticity by Inhibitory Interneurons

(2012) Konrad Lehmann et al.   NEURAL PLASTICITY

The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions

(2011) C. Costa et al.   BLOOD

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Parvalbumin-positive CA1 interneurons are required for spatial working but not for reference memory

(2011) Andrew J Murray et al.   NATURE NEUROSCIENCE

Rac1 and Rac3 GTPases Regulate the Development of Hilar Mossy Cells by Affecting the Migration of Their Precursors to the Hilus

(2011) Roberta Pennucci et al.   PLoS One

Striatum–hippocampus balance: From physiological behavior to interneuronal pathology

(2011) Veronica Ghiglieri et al.   PROGRESS IN NEUROBIOLOGY

Dissection of the Interplay between Class I PI3Ks and Rac Signaling in Phagocytic Functions

(2011) Carlotta Costa et al.   TheScientificWorldJOURNAL

Genetics and Function of Neocortical GABAergic Interneurons in Neurodevelopmental Disorders

(2011) E. Rossignol   NEURAL PLASTICITY

Improved Reversal Learning and Working Memory and Enhanced Reactivity to Novelty in Mice with Enhanced GABAergic Innervation in the Dentate Gyrus

(2010) Fabio Morellini et al.   CEREBRAL CORTEX

The role of Rho GTPase proteins in CNS neuronal migration

(2010) Eve-Ellen Govek et al.   Developmental Neurobiology

Severe clinical course of Hirschsprung disease in a Mowat-Wilson syndrome patient

(2010) R. Smigiel et al.   JOURNAL OF APPLIED GENETICS

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

NMDA Receptor Ablation on Parvalbumin-Positive Interneurons Impairs Hippocampal Synchrony, Spatial Representations, and Working Memory

(2010) Tatiana Korotkova et al.   NEURON

Essential role of Rac1 and Rac3 GTPases in neuronal development

(2009) Sara Corbetta et al.   FASEB JOURNAL

Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation

(2009) Malik Khelfaoui et al.   HUMAN MOLECULAR GENETICS

Rac is involved in the interkinetic nuclear migration of cortical progenitor cells

(2009) Sayaka Minobe et al.   NEUROSCIENCE RESEARCH

GABAergic Hub Neurons Orchestrate Synchrony in Developing Hippocampal Networks

(2009) P. Bonifazi et al.   SCIENCE

Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation

(2008) Hidetoshi Kassai et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hyperactivity and novelty-induced hyperreactivity in mice lacking Rac3

(2007) S CORBETTA et al.   BEHAVIOURAL BRAIN RESEARCH