Development of Pd catalyzed asymmetric additions in the last five years

Enantioselective Aza-Morita-Baylis-Hillman Reactions of Acrylonitrile Catalyzed by Palladium(II) Pincer Complexes havingC2-Symmetric Chiral Bis(imidazoline) Ligands

(2012) Kengo Hyodo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Enantiomerically Enriched Imidazolidin-2-Ones through Asymmetric Palladium-Catalyzed Alkene Carboamination Reactions

(2012) Brett A. Hopkins et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalyzed asymmetric addition of diarylphosphines to N-tosylimines

(2012) Miao Huang et al.   CHEMICAL COMMUNICATIONS

Axially Chiral C2-Symmetric N-Heterocyclic Carbene (NHC) Palladium Complex-Catalyzed Asymmetric Fluorination and Amination of Oxindoles

(2012) Rui Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Indolylnitroalkenes

(2012) Junwei Xing et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Enaminophosphines via Palladacycle-Catalyzed Addition of Ph2PH to α,β-Unsaturated Imines

(2012) Yinhua Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium(II)-Catalyzed Enantioselective Arylation of α-Imino Esters

(2012) Jiayan Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2-Alkylazaarenes to N-Boc Imines and Nitroalkenes

(2012) Daniel Best et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lewis Acid Promoted Highly Diastereoselective Petasis Borono-Mannich Reaction: Efficient Synthesis of Optically Active β,γ-Unsaturated α-Amino Acids

(2012) Yi Li et al.   ORGANIC LETTERS

Palladium(II)-Catalyzed Enantio- and Diastereoselective Synthesis of Pyrrolidine Derivatives

(2012) Ranjan Jana et al.   ORGANIC LETTERS

Palladacycle-Catalyzed Asymmetric Intermolecular Construction of Chiral Tertiary P-Heterocycles by Stepwise Addition of H–P–H Bonds to Bis(enones)

(2012) Yinhua Huang et al.   ORGANOMETALLICS

Chiral Phosphapalladacycles as Efficient Catalysts for the Asymmetric Hydrophosphination of Substituted Methylidenemalonate Esters: Direct Access to Functionalized Tertiary Chiral Phosphines

(2012) Chang Xu et al.   ORGANOMETALLICS

Rh/chiral sulfinylphosphine catalyzed asymmetric 1,4-addition of arylboronic acids to chalcones

(2012) Guihua Chen et al.   TETRAHEDRON

Chiral sulfoxide–olefin ligands: tunable stereoselectivity in Rh-catalyzed asymmetric 1,4-additions

(2012) Guihua Chen et al.   TETRAHEDRON

Rhodium/diene-catalyzed asymmetric arylation of N-Boc-protected α,β-unsaturated δ-lactam with arylboronic acids: enantioselective synthesis of 4-aryl-2-piperidinones

(2012) Zhi-Tao He et al.   TETRAHEDRON

A N-heterocyclic carbene (NHC) platinum complex as pre-catalyst for the intramolecular hydroamination of olefins with secondary alkylamines and oxidative amination of ω-alkenic amines

(2012) Rui Zhang et al.   TETRAHEDRON

Rh(I)-catalyzed asymmetric addition of arylboronic acids to NH isatins

(2012) Jiangyang Gui et al.   TETRAHEDRON-ASYMMETRY

Enantioselective Reaction of Imines and Benzyl Nitriles Using Palladium Pincer Complexes withC2-Symmetric Chiral Bis(imidazoline)s

(2011) Kengo Hyodo et al.   ADVANCED SYNTHESIS & CATALYSIS

Rhodium-Catalyzed, Highly Enantioselective 1,2-Addition of Aryl Boronic Acids to α-Ketoesters and α-Diketones Using Simple, Chiral Sulfur-Olefin Ligands

(2011) Ting-Shun Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Sulfoxide-Olefin Ligands: Completely Switchable Stereoselectivity in Rhodium-Catalyzed Asymmetric Conjugate Additions

(2011) Guihua Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalyzed 1,4-addition of diarylphosphines to α,β-unsaturated N-acylpyrroles

(2011) Dan Du et al.   CHEMICAL COMMUNICATIONS

Design of N-sulfinyl homoallylic amines as novel sulfinamide-olefin hybrid ligands for asymmetric catalysis: application in Rh-catalyzed enantioselective 1,4-additions

(2011) Shen-Shuang Jin et al.   CHEMICAL COMMUNICATIONS

Palladium(II)-Catalyzed Alkene Functionalization via Nucleopalladation: Stereochemical Pathways and Enantioselective Catalytic Applications

(2011) Richard I. McDonald et al.   CHEMICAL REVIEWS

Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update

(2011) Shu̅ Kobayashi et al.   CHEMICAL REVIEWS

Asymmetric Addition of Arylboronic Acids to Cumulene Derivatives Catalyzed by Axially Chiral N-Heterocyclic Carbene-Pd2+ Complexes

(2011) Zhen Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed Highly Enantioselective Addition of Arylboronic Acids to 2-Nitrostyrenes by tert-Butanesulfinylphosphine Ligand

(2011) Feng Lang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed Enantioselective Conjugate Addition of Sodium Tetraarylborates to 2,3-Dihydro-4-pyridones and 4-Quinolones by Using (R,R)-1,2-Bis(tert-butylsulfinyl)benzene as a Ligand

(2011) Xiangyang Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cu-Catalyzed Enantioselective 1,4-Additions of Aryl-Grignard Reagents to Cyclohexenone in the Presence of TADDOL-Derived Phosphane-Phosphite Ligands

(2011) Qaseem Naeemi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Chiral Heterodisulfoxide Ligands in Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to Chromenones

(2011) Fuzhong Han et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Enantiomerically Pure P-Stereogenic Diphosphacrowns and Their Palladium Complexes

(2011) Yasuhiro Morisaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters

(2011) Kotaro Kikushima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of Stable Oxetenes via Lewis Acid-Promoted [2 + 2] Cycloaddition

(2011) Kohsuke Aikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Palladium Catalyzed Asymmetric Addition of Oxindoles and Allenes: An Atom-Economical Versatile Method for the Construction of Chiral Indole Alkaloids

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ru/Me-BIPAM-Catalyzed Asymmetric Addition of Arylboronic Acids to Aliphatic Aldehydes and α-Ketoesters

(2011) Yasunori Yamamoto et al.   MOLECULES

Highly diastereoselective Friedel–Crafts reaction of arenes with N-tert-butanesulfinylimino ester towards the efficient synthesis of α-arylglycines

(2011) Yi Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Design of N-cinnamyl sulfinamides as new sulfur-containing olefin ligands for asymmetric catalysis: achieving structural simplicity with a categorical linear framework

(2011) Shen-Shuang Jin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed 1,4-Addition of Diarylphosphines to α,β-Unsaturated Aldehydes

(2011) Yun-Rong Chen et al.   ORGANIC LETTERS

Direct Synthesis of Chiral Tertiary DiphosphinesviaPd(II)-Catalyzed Asymmetric Hydrophosphination of Dienones

(2011) Yinhua Huang et al.   ORGANIC LETTERS

Catalytic Asymmetric Addition of Arylboronic Acids to Isatins usingC2-Symmetric CationicN-Heterocyclic Carbenes (NHCs) Pd2+Diaqua Complexes as Catalysts

(2011) Zhen Liu et al.   ORGANIC LETTERS

Design of Chiral Sulfoxide–Olefins as a New Class of Sulfur-Based Olefin Ligands for Asymmetric Catalysis

(2011) Wei-Yi Qi et al.   ORGANIC LETTERS

Unsymmetrical Chiral PCN Pincer Palladium(II) and Nickel(II) Complexes with Aryl-Based Aminophosphine–Imidazoline Ligands: Synthesis via Aryl C–H Activation and Asymmetric Addition of Diarylphosphines to Enones

(2011) Ming-Jun Yang et al.   ORGANOMETALLICS

Highly enantioselective Friedel–Crafts alkylation of indole and pyrrole with β,γ-unsaturated α-ketoester catalyzed by chiral dicationic palladium complex

(2011) Kohsuke Aikawa et al.   TETRAHEDRON LETTERS

Rhodium-catalyzed Michael addition of arylboronic acids to 3-alkylenyloxindoles: asymmetric synthesis of functionalized oxindoles

(2011) Xiangyang Zhang et al.   TETRAHEDRON LETTERS

tert-Butanesulfinylphosphines: Simple Chiral Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Electron-Deficient Olefins

(2010) Feng Lang et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Diastereoselective Indium-Mediated Allenylation of N-tert-Butanesulfinyl Imino Ester: Efficient Synthesis of Optically Active α-Allenylglycines

(2010) Shen-Shuang Jin et al.   ADVANCED SYNTHESIS & CATALYSIS

Rhodium-Catalyzed Asymmetric Conjugate Addition of Organoboronic Acids to Nitroalkenes Using Chiral Bicyclo[3.3.0] Diene Ligands

(2010) Zhi-Qian Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium/diene-catalyzed asymmetric arylation of N-sulfonyl indolylimines: a new access to highly optically active α-aryl 3-indolyl-methanamines

(2010) Hong-Yu Yang et al.   CHEMICAL COMMUNICATIONS

Dramatic lithium chloride effect on the reaction stereocontrol in Zn-mediated asymmetric cinnamylation: highly practical synthesis of β-aryl homoallylic amines

(2010) Min Liu et al.   CHEMICAL COMMUNICATIONS

Palladium(ii)-catalyzed asymmetric hydrophosphination of enones: efficient access to chiral tertiary phosphines

(2010) Yinhua Huang et al.   CHEMICAL COMMUNICATIONS

Highly diastereoselective Friedel–Crafts reaction of indoles with an N-tert-butanesulfinylimino ester: an efficient and practical approach to enantiomerically enriched α-(3-indolyl)glycines

(2010) Du-Ming Ji et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Enantioselective Ene and Aldol Reactions with Isatins, Keto Esters, and Diketones: Reliable Approach to Chiral Tertiary Alcohols

(2010) Kohsuke Aikawa et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric 1,4-Addition of Arylboronic Acids to 2,3-Dihydro-4-pyridones Catalyzed by Axially Chiral NHC−Pd(II) Complexes

(2010) Qin Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Construction of Highly Substituted Pyrrolidines by Palladium-Catalyzed Asymmetric [3+2] Cycloaddition of Trimethylenemethane with Ketimines

(2010) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

AC2-Symmetric Chiral Bis-Sulfoxide Ligand in a Rhodium-Catalyzed Reaction: Asymmetric 1,4-Addition of Sodium Tetraarylborates to Chromenones

(2010) Jun Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Palladium-Catalyzed Carboamination Reactions for the Synthesis of Enantiomerically Enriched 2-(Arylmethyl)- and 2-(Alkenylmethyl)pyrrolidines

(2010) Duy N. Mai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to Enones toward the Synthesis of Chiral Phosphines

(2010) Jian-Jun Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Alkynylation of Trifluoropyruvate with Alkynylsilanes Catalyzed by the BINAP−Pd Complex: Access to α-Trifluoromethyl-Substituted Tertiary Alcohols

(2010) Kohsuke Aikawa et al.   ORGANIC LETTERS

Catalytic Enantioselective Addition of Cyclic β-Keto Esters with Activated Olefins and N-Boc Imines Using ChiralC2-Symmetric Cationic Pd2+N-Heterocyclic Carbene (NHC) Diaqua Complexes

(2010) Zhen Liu et al.   ORGANOMETALLICS

Asymmetric 1,4-addition of organoboronic acids to α,β-unsaturated ketones and 1,2-addition to aldehydes catalyzed by a palladium complex with a ferrocene-based phosphine ligand

(2010) Yoshinori Suzuma et al.   TETRAHEDRON-ASYMMETRY

Palladium-catalyzed asymmetric umpolung allylation of imines with allylic alcohols

(2010) Xiang-Chen Qiao et al.   TETRAHEDRON-ASYMMETRY

Axially chiral C2-symmetric N-heterocyclic carbene (NHC) palladium complexes-catalyzed asymmetric arylation of aldehydes with arylboronic acids

(2010) Rui Zhang et al.   TETRAHEDRON-ASYMMETRY

Pd(II)-catalyzed and diethylzinc-mediated asymmetric umpolung allylation of aldehydes in the presence of chiral phosphine-Schiff base type ligands

(2010) Jia-Jun Jiang et al.   TETRAHEDRON-ASYMMETRY

Chiral Pd aqua complex-catalyzed asymmetric C–C bond-forming reactions: a Brønsted acid–base cooperative system

(2009) Mikiko Sodeoka et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Enantioselective Addition of Two Distinct Nucleophiles across Alkenes Capable of Quinone Methide Formation

(2009) Katrina H. Jensen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aryl tert-butyl sulfoxide-promoted highly enantioselective addition of allyltrichlorosilane to aldehydes

(2009) Peng Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Kinetic Resolution of Racemic 1-Alkyl-2-methylenecyclopropanes via Palladium-Catalyzed Silaborative C−C Cleavage

(2009) Toshimichi Ohmura et al.   ORGANIC LETTERS

Catalytic Enantioselective Arylation ofN-Tosylarylimines with Arylboronic Acids UsingC2-Symmetric CationicN-Heterocyclic Carbene Pd2+Diaquo Complexes

(2009) Guang-Ning Ma et al.   ORGANIC LETTERS

Pd(II)/tBu-quinolineoxazoline: An Air-Stable and Modular Chiral Catalyst System for Enantioselective Oxidative Cascade Cyclization

(2009) Wei He et al.   ORGANIC LETTERS

Chiral Bis(NHC)−Palladium(II) Complex Catalyzed and Diethylzinc-Mediated Enantioselective Umpolung Allylation of Aldehydes

(2009) Wenfeng Wang et al.   ORGANOMETALLICS

Palladium(II)/2,2′-bipyridine-catalyzed addition of arylboronic acids to N-tosyl-arylaldimines

(2009) Huixiong Dai et al.   TETRAHEDRON LETTERS

Efficient chirality switching in the asymmetric addition of indole to N-tosylarylimines in the presence of axially chiral cyclometalated bidentate N-heterocyclic carbene palladium(II) complexes

(2009) Zhen Liu et al.   TETRAHEDRON-ASYMMETRY

An Advance on ExploringN-tert-Butanesulfinyl Imines in Asymmetric Synthesis of Chiral Amines

(2008) Guo-Qiang Lin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to α-Ketoesters

(2008) Hai-Feng Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Bidentate Bis(N-Heterocyclic Carbene)-Based Palladium Complexes Bearing Carboxylate Ligands: Highly Effective Catalysts for the Enantioselective Conjugate Addition of Arylboronic Acids to Cyclic Enones

(2008) Tao Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Easily AccessibleC2-Symmetric Chiral Bicyclo[3.3.0] Dienes as Ligands for Rhodium-Catalyzed Asymmetric 1,4-Addition

(2008) Chen-Guo Feng et al.   Chemistry-An Asian Journal

PdII-Catalyzed Asymmetric Addition Reactions of 1,3-Dicarbonyl Compounds: Mannich-Type Reactions withN-Boc Imines and Three-Component Aminomethylation

(2008) Yoshitaka Hamashima et al.   Chemistry-An Asian Journal

Mechanistic Studies on the Catalytic Asymmetric Mannich-Type Reaction with Dihydroisoquinolines and Development of Oxidative Mannich-Type Reactions Starting from Tetrahydroisoquinolines

(2008) Christian Dubs et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Novel Enantiopure BiphenylP,N-Ligands and Application in Palladium-Catalyzed Asymmetric Addition of Arylboronic Acids toN-Benzylisatin

(2008) Hongshan Lai et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Practical Catalytic Asymmetric 1,4-Addition of Arylboronic Acids in Water Using New Hydrophilic Chiral Bicyclo[3.3.0] Diene Ligands

(2008) Chen-Guo Feng et al.   ORGANIC LETTERS

Orthoplatinated Triarylphosphite as a Highly Efficient Catalyst for Addition Reactions of Arylboronic Acids with Aldehydes: Low Catalyst Loading Catalysis and a New Tandem Reaction Sequence

(2008) Yuan-Xi Liao et al.   ORGANIC LETTERS

Enantioselective Arylative Cyclization of Allenyl Aldehydes with Arylboronic Acids under Pd(II)-diphosphine Catalysis

(2008) Hirokazu Tsukamoto et al.   ORGANIC LETTERS