Disruption of the ribosomal P complex leads to stress-induced autophagy

Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival

(2014) Juliana Navarro-Yepes et al.   ANTIOXIDANTS & REDOX SIGNALING

Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells

(2014) Shweta Shrivastava et al.   APOPTOSIS

Autophagy following heat stress: The role of aging and protein nitration

(2014) Jamie M. Swanlund et al.   Autophagy

Involvement of autophagy in hypoxic-excitotoxic neuronal death

(2014) Vanessa Ginet et al.   Autophagy

An inhibition of p62/SQSTM1 caused autophagic cell death of several human carcinoma cells

(2014) Kaito Nihira et al.   CANCER SCIENCE

p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine

(2014) Fang Zheng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

RPLP1, a Crucial Ribosomal Protein for Embryonic Development of the Nervous System

(2014) Laura Perucho et al.   PLoS One

BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production

(2013) Yunha Kim et al.   Autophagy

A Novel Anticancer Agent, 8-Methoxypyrimido[4′,5′:4,5]thieno(2,3-b) Quinoline-4(3H)-One Induces Neuro 2a Neuroblastoma Cell Death through p53-Dependent, Caspase-Dependent and -Independent Apoptotic Pathways

(2013) Upasana Sahu et al.   PLoS One

Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes

(2013) M Hafner Česen et al.   Cell Death & Disease

The VMP1-Beclin 1 interaction regulates autophagy induction

(2013) Maria I. Molejon et al.   Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells

(2012) Kerrie L. May et al.   FEBS Journal

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

(2012) Jeffrey M. Axten et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effects of Niacin Restriction on Sirtuin and PARP Responses to Photodamage in Human Skin

(2012) Claudia A. Benavente et al.   PLoS One

Redox Regulation of p53, Redox Effectors Regulated by p53: A Subtle Balance

(2011) Agnès Maillet et al.   ANTIOXIDANTS & REDOX SIGNALING

Biomarkers of Breast Cancer Apoptosis Induced by Chemotherapy and TRAIL

(2011) Sharon Leong et al.   JOURNAL OF PROTEOME RESEARCH

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

(2011) Brian F. Teske et al.   MOLECULAR BIOLOGY OF THE CELL

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

The In Vivo Role of the RP-Mdm2-p53 Pathway in Signaling Oncogenic Stress Induced by pRb Inactivation and Ras Overexpression

(2011) Wenqi Pan et al.   PLoS One

siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

(2011) Alix Bee et al.   PLoS One

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway

(2010) Susana Llanos et al.   CELL CYCLE

Expression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumors

(2010) Ana Artero-Castro et al.   HUMAN PATHOLOGY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Apoptosis after Autoimmune Regulator Expression in Epithelial Cells Revealed by a Combined Quantitative Proteomics Approach

(2010) Nuria Colomé et al.   JOURNAL OF PROTEOME RESEARCH

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk

(2010) Ka-Ming Lee et al.   NUCLEIC ACIDS RESEARCH

Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

(2010) Chew Hooi Wong et al.   PLoS One

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

(2009) J. M. McClung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells

(2009) Jie Li et al.   ANNALS OF SURGICAL ONCOLOGY

Signaling to p53: Ribosomal Proteins Find Their Way

(2009) Yanping Zhang et al.   CANCER CELL

Rplp1 bypasses replicative senescence and contributes to transformation

(2009) A. Artero-Castro et al.   EXPERIMENTAL CELL RESEARCH

Apoptosis and autophagy: Regulation of apoptosis by DNA damage signalling - roles of p53, p73 and HIPK2

(2009) Nadja Bitomsky et al.   FEBS Journal

Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity

(2009) S. Wilkinson et al.   GENES & DEVELOPMENT

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Functional characterization of ribosomal P1/P2 proteins in human cells

(2008) Francisco Martinez-Azorin et al.   BIOCHEMICAL JOURNAL

The Catalytic Subunit of Shiga-like Toxin 1 Interacts with Ribosomal Stalk Proteins and is Inhibited by Their Conserved C-Terminal Domain

(2008) Andrew J. McCluskey et al.   JOURNAL OF MOLECULAR BIOLOGY

The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain inSaccharomyces cerevisiae

(2008) Jia-Chi Chiou et al.   MOLECULAR MICROBIOLOGY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY