The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors

An individual with blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) and additional features expands the phenotype associated with mutations inKAT6B

(2014) Hung-Chun Yu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

How to make a hippocampal dentate gyrus granule neuron

(2014) D. X. Yu et al.   DEVELOPMENT

Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos

(2014) Linya You et al.   Epigenetics

Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain

(2014) Mulu Y. Lubula et al.   FEBS LETTERS

Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexes

(2013) Brianna J Klein et al.   Epigenetics

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

(2013) M.-E. Lalonde et al.   GENES & DEVELOPMENT

Tbr2 Expression in Cajal-Retzius Cells and Intermediate Neuronal Progenitors Is Required for Morphogenesis of the Dentate Gyrus

(2013) R. D. Hodge et al.   JOURNAL OF NEUROSCIENCE

Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli

(2013) Brian T. Weinert et al.   MOLECULAR CELL

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling

(2013) Abderrahmane Kaidi et al.   NATURE

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

(2013) Jens Füllgrabe et al.   NATURE

MOZ increases p53 acetylation and premature senescence through its complex formation with PML

(2013) S. Rokudai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MOZ-Mediated Repression ofp16INK4aIs Critical for the Self-Renewal of Neural and Hematopoietic Stem Cells

(2013) Flor M. Perez-Campo et al.   STEM CELLS

De Novo Mutations of the Gene Encoding the Histone Acetyltransferase KAT6B Cause Genitopatellar Syndrome

(2012) Michael A. Simpson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome

(2012) Philippe M. Campeau et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exploring the Yeast Acetylome Using Functional Genomics

(2012) Supipi Kaluarachchi Duffy et al.   CELL

A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis

(2012) Ruth Simon et al.   EMBO JOURNAL

Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells

(2012) B. N. Sheikh et al.   JOURNAL OF CELL SCIENCE

Foxg1 Has an Essential Role in Postnatal Development of the Dentate Gyrus

(2012) C. Tian et al.   JOURNAL OF NEUROSCIENCE

Tbr2 Is Essential for Hippocampal Lineage Progression from Neural Stem Cells to Intermediate Progenitors and Neurons

(2012) R. D. Hodge et al.   JOURNAL OF NEUROSCIENCE

SIRT1 Negatively Regulates the Activities, Functions, and Protein Levels of hMOF and TIP60

(2012) L. Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

Function and Molecular Mechanism of Acetylation in Autophagy Regulation

(2012) C. Yi et al.   SCIENCE

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

Whole-Exome-Sequencing Identifies Mutations in Histone Acetyltransferase Gene KAT6B in Individuals with the Say-Barber-Biesecker Variant of Ohdo Syndrome

(2011) Jill Clayton-Smith et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis

(2011) Y. Mishima et al.   BLOOD

Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274

(2011) Bingfa Sun et al.   CELL RESEARCH

Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin

(2011) Lu Lu et al.   CELL RESEARCH

MYST protein acetyltransferase activity requires active site lysine autoacetylation

(2011) Hua Yuan et al.   EMBO JOURNAL

Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome–like phenotype and hyperactivated MAPK signaling in humans and mice

(2011) Michael Kraft et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural and Histone Binding Ability Characterizations of Human PWWP Domains

(2011) Hong Wu et al.   PLoS One

Maintenance of Neuronal Laterality in Caenorhabditis elegans Through MYST Histone Acetyltransferase Complex Components LSY-12, LSY-13 and LIN-49

(2010) M. M. O'Meara et al.   GENETICS

SIRT1 Regulates Autoacetylation and Histone Acetyltransferase Activity of TIP60

(2010) Jiadong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HBO1 Is Required for H3K14 Acetylation and Normal Transcriptional Activity during Embryonic Development

(2010) A. J. Kueh et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

(2010) Alessandro Vezzoli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis

(2010) Alfonso Lavado et al.   PLOS BIOLOGY

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Brpf1, a subunit of the MOZ histone acetyl transferase complex, maintains expression of anterior and posterior Hox genes for proper patterning of craniofacial and caudal skeletons

(2009) Kenta Hibiya et al.   DEVELOPMENTAL BIOLOGY

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

(2009) Rebecca Favaro et al.   NATURE NEUROSCIENCE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Neurogenin 2 has an essential role in development of the dentate gyrus

(2008) C. Galichet et al.   DEVELOPMENT

The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity

(2008) K. Laue et al.   DEVELOPMENT

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

(2008) S. J. Arnold et al.   GENES & DEVELOPMENT

Lysine Acetylation Is a Highly Abundant and Evolutionarily Conserved Modification inEscherichia Coli

(2008) Junmei Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes

(2008) M. Ullah et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

A role for adult TLX-positive neural stem cells in learning and behaviour

(2008) Chun-Li Zhang et al.   NATURE

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

(2008) Young-Goo Han et al.   NATURE NEUROSCIENCE