SIRT1 Negatively Regulates the Activities, Functions, and Protein Levels of hMOF and TIP60

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274

(2011) Bingfa Sun et al.   CELL RESEARCH

Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin

(2011) Lu Lu et al.   CELL RESEARCH

MYST protein acetyltransferase activity requires active site lysine autoacetylation

(2011) Hua Yuan et al.   EMBO JOURNAL

SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities

(2011) L. Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53

(2011) Céline Charvet et al.   MOLECULAR CELL

The RING Finger Protein MSL2 in the MOF Complex Is an E3 Ubiquitin Ligase for H2B K34 and Is Involved in Crosstalk with H3 K4 and K79 Methylation

(2011) Lipeng Wu et al.   MOLECULAR CELL

A SIRT1-LSD1 Corepressor Complex Regulates Notch Target Gene Expression and Development

(2011) Peter Mulligan et al.   MOLECULAR CELL

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1

(2011) Jan Kadlec et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

SIRT1 Regulates Autoacetylation and Histone Acetyltransferase Activity of TIP60

(2010) Jiadong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA

(2010) Wei Fan et al.   MOLECULAR CELL

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX

(2009) Kazutsune Yamagata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization

(2009) J. van Loosdregt et al.   BLOOD

Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome

(2009) M. Schwaiger et al.   GENES & DEVELOPMENT

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

(2009) Yong Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

(2009) Jinping Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

hSirT1-Dependent Regulation of the PCAF-E2F1-p73 Apoptotic Pathway in Response to DNA Damage

(2009) N. Pediconi et al.   MOLECULAR AND CELLULAR BIOLOGY

Two Mammalian MOF Complexes Regulate Transcription Activation by Distinct Mechanisms

(2009) Xiangzhi Li et al.   MOLECULAR CELL

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Histone H4 lysine 16 acetylation regulates cellular lifespan

(2009) Weiwei Dang et al.   NATURE

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60

(2009) Yingli Sun et al.   NATURE CELL BIOLOGY

A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics

(2009) Jürgen Cox et al.   Nature Protocols

Protein deacetylation by SIRT1: An emerging key post-translational modification in metabolic regulation

(2009) Jiujiu Yu et al.   PHARMACOLOGICAL RESEARCH

Regulation of Hypoxia-Inducible Factor 2  Signaling by the Stress-Responsive Deacetylase Sirtuin 1

(2009) E. M. Dioum et al.   SCIENCE

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

Regulation of WRN Protein Cellular Localization and Enzymatic Activities by SIRT1-mediated Deacetylation

(2008) Kai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY

Mof (MYST1 or KAT8) Is Essential for Progression of Embryonic Development Past the Blastocyst Stage and Required for Normal Chromatin Architecture

(2008) T. Thomas et al.   MOLECULAR AND CELLULAR BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY