Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

The Atypical Cadherin Fat Directly Regulates Mitochondrial Function and Metabolic State

(2014) Anson Sing et al.   CELL

A Drosophila Genetic Resource of Mutants to Study Mechanisms Underlying Human Genetic Diseases

(2014) Shinya Yamamoto et al.   CELL

Activity-Driven Local ATP Synthesis Is Required for Synaptic Function

(2014) Vidhya Rangaraju et al.   CELL

Large-scale identification of chemically induced mutations inDrosophila melanogaster

(2014) Nele A. Haelterman et al.   GENOME RESEARCH

Loss of LRPPRC causes ATP synthase deficiency

(2014) A. Mourier et al.   HUMAN MOLECULAR GENETICS

The Mef2 Transcription Network Is Disrupted in Myotonic Dystrophy Heart Tissue, Dramatically Altering miRNA and mRNA Expression

(2014) Auinash Kalsotra et al.   Cell Reports

The Retromer Complex Is Required for Rhodopsin Recycling and Its Loss Leads to Photoreceptor Degeneration

(2014) Shiuan Wang et al.   PLOS BIOLOGY

Regulation of pyruvate metabolism and human disease

(2013) Lawrence R. Gray et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genes and mutations causing retinitis pigmentosa

(2013) S P Daiger et al.   CLINICAL GENETICS

A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila

(2013) J. Bischof et al.   DEVELOPMENT

The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit

(2013) Ke Zhang et al.   JOURNAL OF CELL BIOLOGY

Depletion of PtdIns(4,5)P2 underlies retinal degeneration in Drosophila trp mutants

(2013) S. Sengupta et al.   JOURNAL OF CELL SCIENCE

Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion

(2013) S. G. Rolland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rhodopsin homeostasis and retinal degeneration: lessons from the fly

(2013) Bo Xiong et al.   TRENDS IN NEUROSCIENCES

The post-transcriptional life of mammalian mitochondrial RNA

(2012) Joanna Rorbach et al.   BIOCHEMICAL JOURNAL

GPI biosynthesis is essential for rhodopsin sorting at the trans-Golgi network in Drosophila photoreceptors

(2012) T. Satoh et al.   DEVELOPMENT

Oxidative Phosphorylation, Not Glycolysis, Powers Presynaptic and Postsynaptic Mechanisms Underlying Brain Information Processing

(2012) C. N. Hall et al.   JOURNAL OF NEUROSCIENCE

Role of Rhodopsin and Arrestin Phosphorylation in Retinal Degeneration of Drosophila

(2012) I. Kristaponyte et al.   JOURNAL OF NEUROSCIENCE

Cytosolic Calcium Coordinates Mitochondrial Energy Metabolism with Presynaptic Activity

(2012) A. K. Chouhan et al.   JOURNAL OF NEUROSCIENCE

The optic nerve: A “mito-window” on mitochondrial neurodegeneration

(2012) Alessandra Maresca et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Mitochondrial disorders as windows into an ancient organelle

(2012) Scott B. Vafai et al.   NATURE

Synaptic Energy Use and Supply

(2012) Julia J. Harris et al.   NEURON

LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria

(2012) Takeshi Chujo et al.   NUCLEIC ACIDS RESEARCH

Frequency-dependent mitochondrial Ca2+ accumulation regulates ATP synthesis in pancreatic β cells

(2012) Andrei I. Tarasov et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Drosophila visual transduction

(2012) Craig Montell   TRENDS IN NEUROSCIENCES

Crag Is a GEF for Rab11 Required for Rhodopsin Trafficking and Maintenance of Adult Photoreceptor Cells

(2012) Bo Xiong et al.   PLOS BIOLOGY

Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans

(2012) Vafa Bayat et al.   PLOS BIOLOGY

The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

(2012) Sven Vilain et al.   PLoS Genetics

The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome

(2012) R Kimberley Cook et al.   GENOME BIOLOGY

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

Mitochondrial disorders and the eye

(2011) Samantha A. Schrier et al.   CURRENT OPINION IN OPHTHALMOLOGY

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

(2011) Benedetta Ruzzenente et al.   EMBO JOURNAL

Molecular genetics of retinal degeneration: A Drosophila perspective

(2011) Bih-Hwa Shieh   FLY

Loss of Daylight Vision in Retinal Degeneration: Are Oxidative Stress and Metabolic Dysregulation to Blame?

(2011) Claudio Punzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

The Bicoid Stability Factor Controls Polyadenylation and Expression of Specific Mitochondrial mRNAs in Drosophila melanogaster

(2011) Ana Bratic et al.   PLoS Genetics

Mitochondrial and Nuclear Genomic Responses to Loss ofLRPPRCExpression

(2010) Vishal M. Gohil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurologic Dysfunction and Male Infertility inDrosophila porinMutants

(2010) Brett H. Graham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That Regulates Posttranscriptional Gene Expression in Mitochondria

(2010) Florin Sasarman et al.   MOLECULAR BIOLOGY OF THE CELL

Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait

(2010) Alan F. Wright et al.   NATURE REVIEWS GENETICS

Mitochondrial Dysfunction in NnaD Mutant Flies and Purkinje Cell Degeneration Mice Reveals a Role for Nna Proteins in Neuronal Bioenergetics

(2010) Lisa Chakrabarti et al.   NEURON

Arrestin Translocation Is Stoichiometric to Rhodopsin Isomerization and Accelerated by Phototransduction in Drosophila Photoreceptors

(2010) Akiko K. Satoh et al.   NEURON

Nonlinear coupling between cerebral blood flow, oxygen consumption, and ATP production in human visual cortex

(2010) A.-L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Synaptic Vesicle-Associated Ca2+ Channel Promotes Endocytosis and Couples Exocytosis to Endocytosis

(2009) Chi-Kuang Yao et al.   CELL

Methylation of 12S rRNA Is Necessary for In Vivo Stability of the Small Subunit of the Mammalian Mitochondrial Ribosome

(2009) Metodi D. Metodiev et al.   Cell Metabolism

Characterization of mature mitochondrial transcripts in Drosophila, and the implications for the tRNA punctuation model in arthropods

(2009) James B. Stewart et al.   GENE

Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster

(2009) Koen J T Venken et al.   NATURE METHODS

Retinal light damage: Mechanisms and protection

(2009) Daniel T. Organisciak et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Accumulation of Rhodopsin in Late Endosomes Triggers Photoreceptor Cell Degeneration

(2009) Yashodhan Chinchore et al.   PLoS Genetics

ATP Consumption by Mammalian Rod Photoreceptors in Darkness and in Light

(2008) Haruhisa Okawa et al.   CURRENT BIOLOGY

Reactive oxygen species act remotely to cause synapse loss in a Drosophila model of developmental mitochondrial encephalopathy

(2008) J. D. Mast et al.   DEVELOPMENT

Ca2+-Dependent Metarhodopsin Inactivation Mediated by Calmodulin and NINAC Myosin III

(2008) Che-Hsiung Liu et al.   NEURON

The Molecular Mechanisms of OPA1-Mediated Optic Atrophy in Drosophila Model and Prospects for Antioxidant Treatment

(2008) Will Yarosh et al.   PLoS Genetics