Long-Term Tracking of Segmental Bone Healing Mediated by Genetically Engineered Adipose-Derived Stem Cells: Focuses on Bone Remodeling and Potential Side Effects

Review Article: Bone Transplantation and Immune Response

(2016) Hamid Shegarfi et al.   Journal of Orthopaedic Surgery

Baculovirus: an Insect-derived Vector for Diverse Gene Transfer Applications

(2013) Kari J Airenne et al.   MOLECULAR THERAPY

Regenerating Cartilages by Engineered ASCs: Prolonged TGF-β3/BMP-6 Expression Improved Articular Cartilage Formation and Restored Zonal Structure

(2013) Chia-Hsin Lu et al.   MOLECULAR THERAPY

Enhanced and prolonged baculovirus-mediated expression by incorporating recombinase system and in cis elements: a comparative study

(2013) Li-Yu Sung et al.   NUCLEIC ACIDS RESEARCH

Immune responses during healing of massive segmental femoral bone defects mediated by hybrid baculovirus-engineered ASCs

(2012) Chin-Yu Lin et al.   BIOMATERIALS

Augmented healing of critical-size calvarial defects by baculovirus-engineered MSCs that persistently express growth factors

(2012) Chin-Yu Lin et al.   BIOMATERIALS

Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Murine Leukemia

(2012) Dirk Heckl et al.   MOLECULAR THERAPY

Integration Frequency and Intermolecular Recombination of rAAV Vectors in Non-human Primate Skeletal Muscle and Liver

(2012) Ali Nowrouzi et al.   MOLECULAR THERAPY

A Tissue Engineering Solution for Segmental Defect Regeneration in Load-Bearing Long Bones

(2012) J. C. Reichert et al.   Science Translational Medicine

Improved Chondrogenesis and Engineered Cartilage Formation from TGF-β3-Expressing Adipose-Derived Stem Cells Cultured in the Rotating-Shaft Bioreactor

(2012) Chia-Hsin Lu et al.   TISSUE ENGINEERING PART A

A Differential Effect of Bone Morphogenetic Protein-2 and Vascular Endothelial Growth Factor Release Timing on Osteogenesis at Ectopic and Orthotopic Sites in a Large-Animal Model

(2012) Ruth E. Geuze et al.   TISSUE ENGINEERING PART A

Repairing critical-sized calvarial defects with BMSCs modified by a constitutively active form of hypoxia-inducible factor-1α and a phosphate cement scaffold

(2011) Duohong Zou et al.   BIOMATERIALS

The role of adipose-derived stem cells engineered with the persistently expressing hybrid baculovirus in the healing of massive bone defects

(2011) Chin-Yu Lin et al.   BIOMATERIALS

Blood vessel formation in the tissue-engineered bone with the constitutively active form of HIF-1α mediated BMSCs

(2011) Duohong Zou et al.   BIOMATERIALS

Baculovirus as a gene delivery vector: Recent understandings of molecular alterations in transduced cells and latest applications

(2011) Chi-Yuan Chen et al.   BIOTECHNOLOGY ADVANCES

Biosafety Assessment of Human Mesenchymal Stem Cells Engineered by Hybrid Baculovirus Vectors

(2011) Chi-Yuan Chen et al.   MOLECULAR PHARMACEUTICS

“Same Day” Ex-vivo Regional Gene Therapy: A Novel Strategy to Enhance Bone Repair

(2011) Mandeep S Virk et al.   MOLECULAR THERAPY

Enhancement of bone regeneration by gene delivery of BMP2/Runx2 bicistronic vector into adipose-derived stromal cells

(2010) Suk-Jun Lee et al.   BIOMATERIALS

The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells

(2010) Chin-Yu Lin et al.   BIOMATERIALS

Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma

(2010) Philipp Niemeyer et al.   BIOMATERIALS

Adipose-derived stem cells and BMP2: Part 1. BMP2-treated adipose-derived stem cells do not improve repair of segmental femoral defects

(2010) Yu-Fen Chou et al.   CONNECTIVE TISSUE RESEARCH

Baculovirus Gene Delivery: A Flexible Assay Development Tool

(2010) Thomas A. Kost et al.   CURRENT GENE THERAPY

Host Innate Immune Responses Induced by Baculovirus in Mammals

(2010) Takayuki Abe et al.   CURRENT GENE THERAPY

Baculovirus as a Gene Delivery Vector for Cartilage and Bone Tissue Engineering

(2010) Chin-Yu Lin et al.   CURRENT GENE THERAPY

Potential Cancer Gene Therapy by Baculoviral Transduction

(2010) Shu Wang et al.   CURRENT GENE THERAPY

Mesenchymal Stem Cells Expressing Osteogenic and Angiogenic Factors Synergistically Enhance Bone Formation in a Mouse Model of Segmental Bone Defect

(2010) Sanjay Kumar et al.   MOLECULAR THERAPY

Human Adipose Derived Stromal Cells Heal Critical Size Mouse Calvarial Defects

(2010) Benjamin Levi et al.   PLoS One

Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration

(2009) Diederik H.R. Kempen et al.   BIOMATERIALS

Development of a Hybrid Baculoviral Vector for Sustained Transgene Expression

(2009) Wen-Hsin Lo et al.   MOLECULAR THERAPY

Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

(2009) Ute Modlich et al.   MOLECULAR THERAPY

Repair of Tissues by Adult Stem/Progenitor Cells (MSCs): Controversies, Myths, and Changing Paradigms

(2009) Darwin J Prockop   MOLECULAR THERAPY

Dose Effect of Dual Delivery of Vascular Endothelial Growth Factor and Bone Morphogenetic Protein-2 on Bone Regeneration in a Rat Critical-Size Defect Model

(2009) Simon Young et al.   TISSUE ENGINEERING PART A

Adipose Tissue-Derived Stem Cells and Their Application in Bone and Cartilage Tissue Engineering

(2009) Tommaso Rada et al.   TISSUE ENGINEERING PART B-REVIEWS

Influence of short-term adenoviral vector and prolonged lentiviral vector mediated bone morphogenetic protein-2 expression on the quality of bone repair in a rat femoral defect model

(2008) Mandeep Singh Virk et al.   BONE

Nonunions and the Potential of Stem Cells in Fracture-Healing

(2008) Susan S. Tseng et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Orthopedic Gene Therapy in 2008

(2008) Christopher H Evans et al.   MOLECULAR THERAPY