Endothelial Interleukin-6 Defines the Tumorigenic Potential of Primary Human Cancer Stem Cells

Cross talk Initiated by Endothelial Cells Enhances Migration and Inhibits Anoikis of Squamous Cell Carcinoma Cells through STAT3/Akt/ERK Signaling

(2015) Kathleen G. Neiva et al.   NEOPLASIA

Endothelial cell-derived interleukin-6 regulates tumor growth

(2014) Kathleen G Neiva et al.   BMC CANCER

Endothelial Cell-Secreted EGF Induces Epithelial to Mesenchymal Transition and Endows Head and Neck Cancer Cells with Stem-like Phenotype

(2014) Z. Zhang et al.   CANCER RESEARCH

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Orosphere assay: A method for propagation of head and neck cancer stem cells

(2012) Sudha Krishnamurthy et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

The Vascular Stem Cell Niche

(2012) Maria Victoria Gómez-Gaviro et al.   Journal of Cardiovascular Translational Research

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

(2011) Olga A. Guryanova et al.   CANCER CELL

Stromal Niche Cells Protect Early Leukemic FLT3-ITD+ Progenitor Cells against First-Generation FLT3 Tyrosine Kinase Inhibitors

(2011) A. Parmar et al.   CANCER RESEARCH

Cancer Stem Cells in Squamous Cell Carcinoma Switch between Two Distinct Phenotypes That Are Preferentially Migratory or Proliferative

(2011) A. Biddle et al.   CANCER RESEARCH

Absolute requirement for STAT3 function in small-intestine crypt stem cell survival

(2011) J R Matthews et al.   CELL DEATH AND DIFFERENTIATION

SNAIL Regulates Interleukin-8 Expression, Stem Cell–Like Activity, and Tumorigenicity of Human Colorectal Carcinoma Cells

(2011) Wei–Lun Hwang et al.   GASTROENTEROLOGY

Human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by AMP-activated protein kinase

(2011) Eung-Kyun Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

(2011) Olivier Keunen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stromal Endothelial Cells Directly Influence Cancer Progression

(2011) J. W. Franses et al.   Science Translational Medicine

In Situ Identification of Putative Cancer Stem Cells by Multiplexing ALDH1, CD44, and Cytokeratin Identifies Breast Cancer Patients with Poor Prognosis

(2010) Veronique Neumeister et al.   AMERICAN JOURNAL OF PATHOLOGY

A phase I/II study of siltuximab (CNTO 328), an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer

(2010) J-F Rossi et al.   BRITISH JOURNAL OF CANCER

Endothelial Cell-Initiated Signaling Promotes the Survival and Self-Renewal of Cancer Stem Cells

(2010) S. Krishnamurthy et al.   CANCER RESEARCH

DNA Damage-Mediated Induction of a Chemoresistant Niche

(2010) Luke A. Gilbert et al.   CELL

Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS

(2010) Veronika Makó et al.   CYTOMETRY PART A

Tocilizumab for the treatment of rheumatoid arthritis

(2010) Toshio Tanaka et al.   Expert Review of Clinical Immunology

Clinical, pathological and molecular determinants in squamous cell carcinoma of the oral cavity

(2010) Jamil N Al-Swiahb et al.   Future Oncology

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

(2010) Christophe Ginestier et al.   JOURNAL OF CLINICAL INVESTIGATION

Cucurbitacin I Suppressed Stem-Like Property and Enhanced Radiation-Induced Apoptosis in Head and Neck Squamous Carcinoma-Derived CD44+ALDH1+ Cells

(2010) Y.-W. Chen et al.   MOLECULAR CANCER THERAPEUTICS

Cancer stem cells in solid tumors

(2010) Patrick C. Hermann et al.   SEMINARS IN CANCER BIOLOGY

Targeted inhibition of interleukin-6 with CNTO 328 sensitizes pre-clinical models of multiple myeloma to dexamethasone-mediated cell death

(2009) Peter M. Voorhees et al.   BRITISH JOURNAL OF HAEMATOLOGY

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Humanized Anti-Interleukin-6 Receptor Antibody Suppresses Tumor Angiogenesis and In vivo Growth of Human Oral Squamous Cell Carcinoma

(2009) S. Shinriki et al.   CLINICAL CANCER RESEARCH

Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells

(2009) N J Sullivan et al.   ONCOGENE

Inhibition of tumorigenicity and enhancement of radiochemosensitivity in head and neck squamous cell cancer-derived ALDH1-positive cells by knockdown of Bmi-1

(2009) Yu-Chih Chen et al.   ORAL ONCOLOGY

Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

(2009) Hui Wang et al.   STEM CELLS

Interleukin-6 predicts recurrence and survival among head and neck cancer patients

(2008) Sonia A. Duffy et al.   CANCER

Implications of the Cancer Stem-Cell Hypothesis for Breast Cancer Prevention and Therapy

(2008) Madhuri Kakarala et al.   JOURNAL OF CLINICAL ONCOLOGY

Chemotherapy in the treatment of locally advanced head and neck cancer

(2008) Arlene A. Forastiere   JOURNAL OF SURGICAL ONCOLOGY