Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research
出版年份 2015 全文链接
标题
Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research
作者
关键词
Dementia, Cognitive Decline, Systemic Inflammation, Amyloid Precursor Protein, Microglial Priming
出版物
Alzheimers Research & Therapy
Volume 7, Issue 1, Pages 33
出版商
Springer Nature
发表日期
2015-03-23
DOI
10.1186/s13195-015-0117-2
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases
- (2014) Christian Hölscher BIOCHEMICAL SOCIETY TRANSACTIONS
- Obesity and neuroinflammation: A pathway to cognitive impairment
- (2014) Alyson A. Miller et al. BRAIN BEHAVIOR AND IMMUNITY
- Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: Focus on brain indoleamine 2,3-dioxygenase activation
- (2014) Caroline André et al. BRAIN BEHAVIOR AND IMMUNITY
- Glucocorticoid sensitization of microglia in a genetic mouse model of obesity and diabetes
- (2014) Aditi Dey et al. JOURNAL OF NEUROIMMUNOLOGY
- The role of Nox2-derived ROS in the development of cognitive impairment after sepsis
- (2014) Marina S Hernandes et al. Journal of Neuroinflammation
- Obesity Elicits Interleukin 1-Mediated Deficits in Hippocampal Synaptic Plasticity
- (2014) J. R. Erion et al. JOURNAL OF NEUROSCIENCE
- Neurodegeneration by Activation of the Microglial Complement-Phagosome Pathway
- (2014) L.-G. Bodea et al. JOURNAL OF NEUROSCIENCE
- Cerebrospinal fluid markers of neuroinflammation in delirium: A role for interleukin-1β in delirium after hip fracture
- (2014) Eleanor Cape et al. JOURNAL OF PSYCHOSOMATIC RESEARCH
- Aging Exacerbates Obesity-induced Cerebromicrovascular Rarefaction, Neurovascular Uncoupling, and Cognitive Decline in Mice
- (2014) Z. Tucsek et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Long-term cerebral consequences of sepsis
- (2014) Catherine N Widmann et al. LANCET NEUROLOGY
- Microglial priming in neurodegenerative disease
- (2014) V. Hugh Perry et al. Nature Reviews Neurology
- High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology
- (2014) Elysse M. Knight et al. NEUROBIOLOGY OF AGING
- Comparison of the independent and combined effects of sub-chronic therapy with metformin and a stable GLP-1 receptor agonist on cognitive function, hippocampal synaptic plasticity and metabolic control in high-fat fed mice
- (2014) Rachael Lennox et al. NEUROPHARMACOLOGY
- Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia
- (2014) Dana M Niedowicz et al. Acta Neuropathologica Communications
- High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow–derived Macrophages
- (2013) Susana Vacas et al. ANESTHESIOLOGY
- Dissecting phenotypic traits linked to human resilience to Alzheimer’s pathology
- (2013) Beatriz G. Perez-Nievas et al. BRAIN
- Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging
- (2013) Yun-Hee Youm et al. Cell Metabolism
- Association of statin use with risk of dementia: A meta-analysis of prospective cohort studies
- (2013) Yu Song et al. Geriatrics & Gerontology International
- Hormones and diet, but not body weight, control hypothalamic microglial activity
- (2013) Yuanqing Gao et al. GLIA
- Immune Effector Mechanisms Implicated in Atherosclerosis: From Mice to Humans
- (2013) Peter Libby et al. IMMUNITY
- Cyclooxygenase-1-Dependent Prostaglandins Mediate Susceptibility to Systemic Inflammation-Induced Acute Cognitive Dysfunction
- (2013) E. W. Griffin et al. JOURNAL OF NEUROSCIENCE
- Obesity in Aging Exacerbates Blood-Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer's Disease
- (2013) Z. Tucsek et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Il1-β Involvement in Cognitive Impairment after Sepsis
- (2013) Francielle Mina et al. MOLECULAR NEUROBIOLOGY
- Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
- (2013) Guo Zhang et al. NATURE
- CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
- (2013) Frederick J Sheedy et al. NATURE IMMUNOLOGY
- Long-Term Cognitive Impairment after Critical Illness
- (2013) P.P. Pandharipande et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sex-Specific Effects of High Fat Diet on Indices of Metabolic Syndrome in 3xTg-AD Mice: Implications for Alzheimer's Disease
- (2013) Anna M. Barron et al. PLoS One
- Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology
- (2013) J.-P. Michaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice
- (2013) Juan Jose Ramos-Rodriguez et al. PSYCHONEUROENDOCRINOLOGY
- Modulation of Murine Alzheimer Pathogenesis and Behavior by Surgery
- (2012) Junxia X. Tang et al. ANNALS OF SURGERY
- Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study
- (2012) Daniel H. J. Davis et al. BRAIN
- At the extreme end of the psychoneuroimmunological spectrum: Delirium as a maladaptive sickness behaviour response
- (2012) Colm Cunningham et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglia and neurodegeneration: The role of systemic inflammation
- (2012) Colm Cunningham GLIA
- Long-term impact of systemic bacterial infection on the cerebral vasculature and microglia
- (2012) Ursula Püntener et al. Journal of Neuroinflammation
- Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice
- (2012) Dimitrije Krstic et al. Journal of Neuroinflammation
- Prior Pathology in the Basal Forebrain Cholinergic System Predisposes to Inflammation-Induced Working Memory Deficits: Reconciling Inflammatory and Cholinergic Hypotheses of Delirium
- (2012) R. H. Field et al. JOURNAL OF NEUROSCIENCE
- The Cholinergic System and Inflammation: Common Pathways in Delirium Pathophysiology
- (2012) Joaquim Cerejeira et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Statins have therapeutic potential for the treatment of Alzheimer's disease, likely via protection of the neurovascular unit in the AD brain
- (2012) Tomoko Kurata et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Deciphering the mechanism underlying late-onset Alzheimer disease
- (2012) Dimitrije Krstic et al. Nature Reviews Neurology
- ApoE ε4 is associated with eIF2α phosphorylation and impaired learning in young mice
- (2012) Yifat Segev et al. NEUROBIOLOGY OF AGING
- Review: Systemic inflammation and Alzheimer's disease
- (2012) C. Holmes NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Variant TREM2 as Risk Factor for Alzheimer's Disease
- (2012) Harald Neumann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Systematic Review and Meta-Analysis of the Efficacy and Safety of Existing TNF Blocking Agents in Treatment of Rheumatoid Arthritis
- (2012) Kalle J. Aaltonen et al. PLoS One
- Inflammatory Mechanisms in Obesity
- (2011) Margaret F. Gregor et al. Annual Review of Immunology
- Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4
- (2011) Rik F. P. Schelbergen et al. ARTHRITIS AND RHEUMATISM
- Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice
- (2011) Sun Park et al. BMC NEUROSCIENCE
- Brain inflammation is induced by co-morbidities and risk factors for stroke
- (2011) Caroline Drake et al. BRAIN BEHAVIOR AND IMMUNITY
- Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses
- (2011) Matthew G. Frank et al. BRAIN BEHAVIOR AND IMMUNITY
- Obesity is associated with hypothalamic injury in rodents and humans
- (2011) Joshua P. Thaler et al. JOURNAL OF CLINICAL INVESTIGATION
- Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide
- (2011) Angela W Corona et al. Journal of Neuroinflammation
- Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice
- (2011) Stephanos Kyrkanides et al. Journal of Neuroinflammation
- CEREBROSPINAL FLUID INTERLEUKIN-8 LEVELS ARE HIGHER IN PEOPLE WITH HIP FRACTURE WITH PERIOPERATIVE DELIRIUM THAN IN CONTROLS
- (2011) Alasdair M.J. MacLullich et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice
- (2011) Masato Maesako et al. NEUROBIOLOGY OF AGING
- Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes
- (2010) Gyungah Jun ARCHIVES OF NEUROLOGY
- Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNα/β and IL-1β responses in the diseased brain and exacerbates chronic neurodegeneration
- (2010) Robert Field et al. BRAIN BEHAVIOR AND IMMUNITY
- Delirium in Elderly Patients and the Risk of Postdischarge Mortality, Institutionalization, and Dementia
- (2010) Joost Witlox et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling
- (2010) Christopher D. Morrison et al. JOURNAL OF NEUROCHEMISTRY
- Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
- (2010) Seth L Masters et al. NATURE IMMUNOLOGY
- Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium
- (2010) Carol Murray et al. NEUROBIOLOGY OF AGING
- Tumor necrosis factor- triggers a cytokine cascade yielding postoperative cognitive decline
- (2010) N. Terrando et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A deposition in an Alzheimer mouse model with diabetes
- (2010) S. Takeda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cholesterol as a Risk Factor for Dementia and Cognitive Decline: A Systematic Review of Prospective Studies With Meta-Analysis
- (2009) Kaarin J. Anstey et al. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
- Increased atherosclerosis and vascular inflammation in APP transgenic mice with apolipoprotein E deficiency
- (2009) G. Tibolla et al. ATHEROSCLEROSIS
- Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology
- (2009) Fiona E. McAlpine et al. NEUROBIOLOGY OF DISEASE
- Systemic inflammation and disease progression in Alzheimer disease
- (2009) C. Holmes et al. NEUROLOGY
- Epidemiological Pathology of Dementia: Attributable-Risks at Death in the Medical Research Council Cognitive Function and Ageing Study
- (2009) Fiona E. Matthews et al. PLOS MEDICINE
- Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks
- (2008) Alexandra Bour et al. BEHAVIOURAL BRAIN RESEARCH
- Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease
- (2008) Colm Cunningham et al. BIOLOGICAL PSYCHIATRY
- Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
- (2008) M. C. Pott Godoy et al. BRAIN
- Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation
- (2008) Jae Lee et al. Journal of Neuroinflammation
- Time-Course of Cytokines During Delirium in Elderly Patients with Hip Fractures
- (2008) Barbara C. Van Munster et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
- (2008) Clive Holmes et al. LANCET
- Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
- (2007) Jing Chen et al. BRAIN BEHAVIOR AND IMMUNITY
- Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration
- (2007) Karine Palin et al. NEUROBIOLOGY OF DISEASE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started