标题
Economical analysis of saturation mutagenesis experiments
作者
关键词
-
出版物
Scientific Reports
Volume 5, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-07-20
DOI
10.1038/srep10654
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- MDC-Analyzer: A novel degenerate primer design tool for the construction of intelligent mutagenesis libraries with contiguous sites
- (2016) Lixia Tang et al. BIOTECHNIQUES
- Directed evolution of stereoselective enzymes based on genetic selection as opposed to screening systems
- (2014) Carlos G. Acevedo-Rocha et al. JOURNAL OF BIOTECHNOLOGY
- Saturation editing of genomic regions by multiplex homology-directed repair
- (2014) Gregory M. Findlay et al. NATURE
- CRISPR–Cas9-assisted recombineering in Lactobacillus reuteri
- (2014) Jee-Hwan Oh et al. NUCLEIC ACIDS RESEARCH
- Directed evolution of a far-red fluorescent rhodopsin
- (2014) R. S. McIsaac et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution
- (2014) Andrew Currin et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Speeding up Directed Evolution: Combining the Advantages of Solid-Phase Combinatorial Gene Synthesis with Statistically Guided Reduction of Screening Effort
- (2014) Sabrina Hoebenreich et al. ACS Synthetic Biology
- ProxiMAX randomization: a new technology for non-degenerate saturation mutagenesis of contiguous codons
- (2013) Mohammed Ashraf et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Polishing the craft of genetic diversity creation in directed evolution
- (2013) Kang Lan Tee et al. BIOTECHNOLOGY ADVANCES
- Expanding the metabolic engineering toolbox with directed evolution
- (2013) Joseph Abatemarco et al. Biotechnology Journal
- Expanding the Library and Substrate Diversity of the Pyrrolysyl-tRNA Synthetase to Incorporate Unnatural Amino Acids Containing Conjugated Rings
- (2013) Vanessa K. Lacey et al. CHEMBIOCHEM
- Library construction and evaluation for site saturation mutagenesis
- (2013) Bradford Sullivan et al. ENZYME AND MICROBIAL TECHNOLOGY
- Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future
- (2013) Manfred T. Reetz JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Optimal codon randomization via mathematical programming
- (2013) Yuval Nov et al. JOURNAL OF THEORETICAL BIOLOGY
- A Novel Test for Selection on cis-Regulatory Elements Reveals Positive and Negative Selection Acting on Mammalian Transcriptional Enhancers
- (2013) Justin D. Smith et al. MOLECULAR BIOLOGY AND EVOLUTION
- Genome-scale engineering for systems and synthetic biology
- (2013) K. M. Esvelt et al. Molecular Systems Biology
- Precision is essential for efficient catalysis in an evolved Kemp eliminase
- (2013) Rebecca Blomberg et al. NATURE
- Stereoselective Oxidation of Aryl-Substituted Vicinal Diols into Chiral α-Hydroxy Aldehydes by Re-Engineered Propanediol Oxidoreductase
- (2013) Cecilia Blikstad et al. ACS Catalysis
- Elimination of Redundant and Stop Codons during the Chemical Synthesis of Degenerate Oligonucleotides. Combinatorial Testing on the Chromophore Region of the Red Fluorescent Protein mKate
- (2013) Paul Gaytán et al. ACS Synthetic Biology
- A Single Active Site Mutation Inverts Stereoselectivity of 16-Hydroxylation of Testosterone Catalyzed by Engineered Cytochrome P450 BM3
- (2012) Harini Venkataraman et al. CHEMBIOCHEM
- Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed Evolution
- (2012) Rubén Agudo et al. CHEMBIOCHEM
- Tools for genome-wide strain design and construction
- (2012) Nanette R Boyle et al. CURRENT OPINION IN BIOTECHNOLOGY
- Directed evolution: an evolving and enabling synthetic biology tool
- (2012) Ryan E Cobb et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Reducing Codon Redundancy and Screening Effort of Combinatorial Protein Libraries Created by Saturation Mutagenesis
- (2012) Sabrina Kille et al. ACS Synthetic Biology
- When Second Best Is Good Enough: Another Probabilistic Look at Saturation Mutagenesis
- (2011) Yuval Nov APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- P450BM3(CYP102A1): connecting the dots
- (2011) Christopher J. C. Whitehouse et al. CHEMICAL SOCIETY REVIEWS
- Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution
- (2011) Sabrina Kille et al. Nature Chemistry
- Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions
- (2010) Manfred T. Reetz ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- High-Throughput Metabolic Engineering: Advances in Small-Molecule Screening and Selection
- (2010) Jeffrey A. Dietrich et al. Annual Review of Biochemistry
- All-codon scanning identifies p53 cancer rescue mutations
- (2010) Roberta Baronio et al. NUCLEIC ACIDS RESEARCH
- Directed Evolution of an Enantioselective Enoate-Reductase: Testing the Utility of Iterative Saturation Mutagenesis
- (2009) Despinaâ J. Bougioukou et al. ADVANCED SYNTHESIS & CATALYSIS
- Programming cells by multiplex genome engineering and accelerated evolution
- (2009) Harris H. Wang et al. NATURE
- High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
- (2009) Rupali P Patwardhan et al. NATURE BIOTECHNOLOGY
- TrimerDimer: an oligonucleotide-based saturation mutagenesis approach that removes redundant and stop codons
- (2009) Paul Gaytán et al. NUCLEIC ACIDS RESEARCH
- Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates
- (2008) Joaquin Sanchis et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started