Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

Use of Perfluorocarboxylic Acids To Trick Cytochrome P450BM3 into Initiating the Hydroxylation of Gaseous Alkanes

(2011) Norifumi Kawakami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tuning a P450 Enzyme for Methane Oxidation

(2011) Felipe E. Zilly et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Regioselective Biocatalyst for Alkane Activation under Mild Conditions

(2011) Mélanie Bordeaux et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

If CH Bonds Could Talk: Selective CH Bond Oxidation

(2011) Timothy Newhouse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

P450 Fingerprinting Method for Rapid Discovery of Terpene Hydroxylating P450 Catalysts with Diversified Regioselectivity

(2011) Kaidong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions

(2010) Manfred T. Reetz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of cytochrome P450 monooxygenase CYP154H1 from the thermophilic soil bacterium Thermobifida fusca

(2010) Anett Schallmey et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Combinatorial Alanine Substitution Enables Rapid Optimization of Cytochrome P450BM3 for Selective Hydroxylation of Large Substrates

(2010) Jared C. Lewis et al.   CHEMBIOCHEM

Enzyme-mediated oxidations for the chemist

(2010) Frank Hollmann et al.   GREEN CHEMISTRY

Aiming for the Ideal Synthesis

(2010) Tanja Gaich et al.   JOURNAL OF ORGANIC CHEMISTRY

Efficient stereo- and regioselective hydroxylation of alkanes catalysed by a bulky polyoxometalate

(2010) Keigo Kamata et al.   Nature Chemistry

Directed Evolution of an Enantioselective Enoate-Reductase: Testing the Utility of Iterative Saturation Mutagenesis

(2009) Despina J. Bougioukou et al.   ADVANCED SYNTHESIS & CATALYSIS

P450 Enzymes: Their Structure, Reactivity, and Selectivity—Modeled by QM/MM Calculations

(2009) Sason Shaik et al.   CHEMICAL REVIEWS

A Highly Reactive P450 Model Compound I

(2009) Seth R. Bell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Theoretical and Experimental Evaluation of a CYP106A2 Low Homology Model and Production of Mutants with Changed Activity and Selectivity of Hydroxylation

(2008) Michael Lisurek et al.   CHEMBIOCHEM

Identification of selectivity-determining residues in cytochrome P450 monooxygenases: A systematic analysis of the substrate recognition site 5

(2008) Alexander Seifert et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Regioselectivity preference of testosterone hydroxylation by cytochrome P450 3A4

(2008) Yan Zhang et al.   THEORETICAL CHEMISTRY ACCOUNTS

Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites

(2007) Micaela C. Damsten et al.   CHEMICO-BIOLOGICAL INTERACTIONS