A Single Active Site Mutation Inverts Stereoselectivity of 16-Hydroxylation of Testosterone Catalyzed by Engineered Cytochrome P450 BM3
出版年份 2012 全文链接
标题
A Single Active Site Mutation Inverts Stereoselectivity of 16-Hydroxylation of Testosterone Catalyzed by Engineered Cytochrome P450 BM3
作者
关键词
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出版物
CHEMBIOCHEM
Volume 13, Issue 4, Pages 520-523
出版商
Wiley
发表日期
2012-01-25
DOI
10.1002/cbic.201100750
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Role of Protein Plasticity in Computational Rationalization Studies on Regioselectivity in Testosterone Hydroxylation by Cytochrome P450 BM3 Mutants
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- Evolved CYP102A1 (P450BM3) variants oxidise a range of non-natural substrates and offer new selectivity options
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- Altering the regioselectivity of the subterminal fatty acid hydroxylase P450 BM-3 towards γ- and δ-positions
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- Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites
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