Transfer RNA: A dancer between charging and mis-charging for protein biosynthesis

A naturally occurring nonapeptide functionally compensates for the CP1 domain of leucyl-tRNA synthetase to modulate aminoacylation activity

(2012) Min Tan et al.   BIOCHEMICAL JOURNAL

Human cytoplasmic ProX edits mischarged tRNAProwith amino acid but not tRNA specificity

(2012) Liang-Liang Ruan et al.   BIOCHEMICAL JOURNAL

Interdomain communication modulates the tRNA-dependent pre-transfer editing of leucyl-tRNA synthetase

(2012) Min Tan et al.   BIOCHEMICAL JOURNAL

The Mechanism of Pre-transfer Editing in Yeast Mitochondrial Threonyl-tRNA Synthetase

(2012) Jiqiang Ling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase

(2012) Andrés Palencia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Misacylation of tRNA with methionine in Saccharomyces cerevisiae

(2012) E. Wiltrout et al.   NUCLEIC ACIDS RESEARCH

Rational design and directed evolution of a bacterial-type glutaminyl-tRNA synthetase precursor

(2012) L.-T. Guo et al.   NUCLEIC ACIDS RESEARCH

Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote

(2012) Xiao-Long Zhou et al.   NUCLEIC ACIDS RESEARCH

In vivo identification of essential nucleotides in tRNA Leu to its functions by using a constructed yeast tRNA Leu knockout strain

(2012) Qian Huang et al.   NUCLEIC ACIDS RESEARCH

Selection of tRNA charging quality control mechanisms that increase mistranslation of the genetic code

(2012) Srujana S. Yadavalli et al.   NUCLEIC ACIDS RESEARCH

Roles of tRNA in cell wall biosynthesis

(2012) Kiley Dare et al.   Wiley Interdisciplinary Reviews-RNA

Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase

(2011) Ru-Juan Liu et al.   BIOCHEMICAL JOURNAL

Catalytic Mechanism of Sep-tRNA:Cys-tRNA Synthase

(2011) Yuchen Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of tRNA amino acid-accepting end in aminoacylation and its quality control

(2011) Xiao-Long Zhou et al.   NUCLEIC ACIDS RESEARCH

Misacylation of specific nonmethionyl tRNAs by a bacterial methionyl-tRNA synthetase

(2011) T. E. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites

(2011) L. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p23H implicated as cis/trans regulator of AlaXp-directed editing for mammalian cell homeostasis

(2011) M. H. Nawaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transfer RNA-derived fragments: origins, processing, and functions

(2011) Andrew Sobala et al.   Wiley Interdisciplinary Reviews-RNA

Post-transfer editing by a eukaryotic leucyl-tRNA synthetase resistant to the broad-spectrum drug AN2690

(2010) Xiao-Long Zhou et al.   BIOCHEMICAL JOURNAL

Crystal structure of a transfer-ribonucleoprotein particle that promotes asparagine formation

(2010) Mickaël Blaise et al.   EMBO JOURNAL

Partitioning of tRNA-dependent Editing between Pre- and Post-transfer Pathways in Class I Aminoacyl-tRNA Synthetases

(2010) Morana Dulic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions

(2010) Takuhiro Ito et al.   NATURE

Cellular mechanisms that control mistranslation

(2010) Noah M. Reynolds et al.   NATURE REVIEWS MICROBIOLOGY

Cell-specific differences in the requirements for translation quality control

(2010) N. M. Reynolds et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic insights into cognate substrate discrimination during proofreading in translation

(2010) T. Hussain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptotic regulation and tRNA

(2010) Yide Mei et al.   Protein & Cell

Aminoacyl-tRNA Synthesis and Translational Quality Control

(2009) Jiqiang Ling et al.   Annual Review of Microbiology

Two tyrosine residues outside the editing active site in Giardia lamblia leucyl-tRNA synthetase are essential for the post-transfer editing

(2009) Xiao-Long Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Unique Insertion in the CP1 Domain ofGiardia lambliaLeucyl-tRNA Synthetase†

(2009) Xiao-Long Zhou et al.   BIOCHEMISTRY

tRNAs: Cellular barcodes for amino acids

(2009) Rajat Banerjee et al.   FEBS LETTERS

Formation of the tRNALys packaging complex in HIV-1

(2009) Lawrence Kleiman et al.   FEBS LETTERS

tRNA as an active chemical scaffold for diverse chemical transformations

(2009) Christopher S. Francklyn et al.   FEBS LETTERS

Development of the genetic code: Insights from a fungal codon reassignment

(2009) Gabriela R. Moura et al.   FEBS LETTERS

Yeast mitochondrial Gln-tRNAGln is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS

(2009) M. Frechin et al.   GENES & DEVELOPMENT

tRNA-dependent Pre-transfer Editing by Prokaryotic Leucyl-tRNA Synthetase

(2009) Min Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Widespread Distribution of Cell Defense against d-Aminoacyl-tRNAs

(2009) Sandra Wydau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resampling and Editing of Mischarged tRNA Prior to Translation Elongation

(2009) Jiqiang Ling et al.   MOLECULAR CELL

Innate immune and chemically triggered oxidative stress modifies translational fidelity

(2009) Nir Netzer et al.   NATURE

Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma

(2009) Min Guo et al.   NATURE

Biogenesis of glutaminyl-mt tRNAGln in human mitochondria

(2009) A. Nagao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The C-Ala Domain Brings Together Editing and Aminoacylation Functions on One tRNA

(2009) M. Guo et al.   SCIENCE

The Human SepSecS-tRNASec Complex Reveals the Mechanism of Selenocysteine Formation

(2009) S. Palioura et al.   SCIENCE

Amino acid modifications on tRNA†

(2008) Jing Yuan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Unique Residues Crucial for Optimal Editing in Yeast Cytoplasmic Leucyl-tRNA Synthetase Are Revealed by Using a Novel Knockout Yeast Strain

(2008) Peng Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transfer RNA Modulates the Editing Mechanism Used by Class II Prolyl-tRNA Synthetase

(2008) Kathryn E. Splan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

tRNA-independent Pretransfer Editing by Class I Leucyl-tRNA Synthetase

(2008) Bin Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the Evolution of the tRNA-Dependent Amidotransferases, GatCAB and GatDE

(2008) Kelly Sheppard et al.   JOURNAL OF MOLECULAR BIOLOGY

Distinct domains of tRNA synthetase recognize the same base pair

(2008) Kirk Beebe et al.   NATURE

Toward a more complete view of tRNA biology

(2008) Richard Giegé   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recognition of tRNA Leu by Aquifex aeolicus leucyl-tRNA synthetase during the aminoacylation and editing steps

(2008) Peng Yao et al.   NUCLEIC ACIDS RESEARCH

Dual-targeted tRNA-dependent amidotransferase ensures both mitochondrial and chloroplastic Gln-tRNAGln synthesis in plants

(2008) C. Pujol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of tRNA synthetases and connection to genetic code and disease

(2008) Paul Schimmel   PROTEIN SCIENCE