Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

(2012) Jung Min Han et al.   CELL

Leucyl-tRNA Synthetase Controls TORC1 via the EGO Complex

(2012) Grégory Bonfils et al.   MOLECULAR CELL

Design, Synthesis, and Structure−Activity Relationship ofTrypanosoma bruceiLeucyl-tRNA Synthetase Inhibitors as Antitrypanosomal Agents

(2011) Dazhong Ding et al.   JOURNAL OF MEDICINAL CHEMISTRY

Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites

(2011) L. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents

(2010) Yong-Kang Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Editing Mechanism of Aminoacyl-tRNA Synthetases Operates by a Hybrid Ribozyme/Protein Catalyst

(2010) Yohsuke Hagiwara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Modeling of tRNA-assisted mechanism of Arg activation based on a structure of Arg-tRNA synthetase, tRNA, and an ATP analog (ANP)

(2009) Michiko Konno et al.   FEBS Journal

Evolutionary Basis for the Coupled-domain Motions inThermus thermophilusLeucyl-tRNA Synthetase

(2009) Kristina Mary Ellen Weimer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles

(2009) Elena Seiradake et al.   JOURNAL OF MOLECULAR BIOLOGY

Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states

(2008) Ning Shen et al.   NUCLEIC ACIDS RESEARCH