Synthesis, in vitro anticancer activity and SAR studies of arylated imidazo[1,2-a]pyrazine–coumarin hybrids

Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications

(2015) Richa Goel et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

(2014) Kunal Nepali et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase

(2014) Kevin S. Currie et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of new conjugated coumarin–benzimidazole hybrids and their anticancer activity

(2013) Kamaldeep Paul et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Palladium catalyzed novel monoarylation and symmetrical/unsymmetrical diarylation of imidazo[1,2-a]pyrazines and their in vitro anticancer activities

(2013) Richa Goel et al.   RSC Advances

Imidazo[1,2-a]pyrazines as novel PI3K inhibitors

(2012) Sonia Martínez González et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitors

(2011) Hongbo Zeng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Diversity oriented design of various hydrazides and their in vitro evaluation against Mycobacterium tuberculosis H37Rv strains

(2011) Atul Manvar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New diarylureas and diarylamides containing 1,3,4-triarylpyrazole scaffold: Synthesis, antiproliferative evaluation against melanoma cell lines, ERK kinase inhibition, and molecular docking studies

(2011) Won-Kyoung Choi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antitumor agents 292. Design, synthesis and pharmacological study of S- and O-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agents

(2011) Ying Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

N-Fused Imidazoles As Novel Anticancer Agents That Inhibit Catalytic Activity of Topoisomerase IIα and Induce Apoptosis in G1/S Phase

(2011) Ashish T. Baviskar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells

(2010) Nathalie Bouloc et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinases

(2010) Thomas P. Matthews et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and in vitro evaluation of novel coumarin–chalcone hybrids as potential anticancer agents

(2010) Koneni V. Sashidhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure activity relationship studies of imidazo[1,2-a]pyrazine derivatives against cancer cell lines

(2010) Shailaja Myadaraboina et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Protonation Equilibria and Lipophilicity of Sarafloxacin

(2010) Ana I. Caço et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

Highly Suppressing Wild-Type HIV-1 and Y181C Mutant HIV-1 Strains by 10-Chloromethyl-11-demethyl-12-oxo-calanolide A with Druggable Profile

(2010) Hai Xue et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core

(2010) Tao Yu et al.   ACS Medicinal Chemistry Letters