期刊
RSC ADVANCES
卷 4, 期 19, 页码 9885-9892出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra47192f
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资金
- CSIR, New Delhi [02(0034)/11/EMR-II]
- CSIR [09/677(0020)/2013.EMR-I]
Palladium catalyzed Suzuki-Miyaura cross-coupling reactions are reported for the synthesis of monoarylated (at the C8 position) and symmetrical diarylated (at the C6 and C8 positions) imidazo[1,2-a]pyrazines. Monoarylated products have also been used to synthesize unsymmetrical C6/C8 diarylated products. These compounds were screened for in vitro antitumor activities against a preliminary tumor cell line panel assay.
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