Editorial Material
Multidisciplinary Sciences
Mark A. Travis, Chiara Romagnani
Summary: Active control of the immune system is necessary to prevent inflammatory bowel disease. Cell populations that promote the generation of immunosuppressive regulatory T cells in the gut have been identified.
Editorial Material
Multidisciplinary Sciences
Stuart M. Brierley
Summary: Gut infection can trigger localized immune responses that cause harmless foods to be perceived as harmful, leading to persistent pain. Defense against bacterial infection may drive pain when eating food.
Review
Immunology
Anirban Sengupta, Mohammad Azharuddin, Noha Al-Otaibi, Jorma Hinkula
Summary: The use of gold nanoparticles (GNPs) in vaccine development has gained popularity due to their excellent properties in biocompatibility, immune modulation, and antigen delivery. GNPs can effectively combat various pathogens by modulating immune responses of cells and antibodies. Despite their potential toxicity, it is worth further exploring and investing in GNPs for vaccine development.
Review
Biology
Vania Lopez Ruiz, Jacques Robert
Summary: Amphibians play a crucial role in bridging the evolutionary gap between mammals and ancient vertebrates. Understanding their immune system, which is similar to that of mammals, is important for disease research. The African clawed frog, Xenopus laevis, is a good model for studying the immune system, particularly during early development stages. This review summarizes the knowledge about the innate and adaptive immune system of X. laevis and compares it with other amphibians. It also discusses the response of amphibians to viral, bacterial, and fungal infections.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2023)
Review
Food Science & Technology
Cristina Valeria Bulgaru, Daniela Eliza Marin, Gina Cecilia Pistol, Ionelia Taranu
Summary: ZEA is an estrogenic fusariotoxin that affects reproductive health and immune response. It can cause reproductive disorders and impact immune response, with studies showing effects on different types of immune cells and immune organs. Despite the increasing research on the mechanisms of ZEA in modulating immune response, data are currently insufficient and further investigation is needed.
Article
Gastroenterology & Hepatology
Hsin-Chih Lai, Tzu-Lung Lin, Ting-Wen Chen, Yu-Lun Kuo, Chih-Jung Chang, Tsung-Ru Wu, Ching-Chung Shu, Ying-Huang Tsai, Simon Swift, Chia-Chen Lu
Summary: The study found that gut microbiota composition significantly affects cigarette smoking-induced COPD development, and fecal microbiota transplantation can restore COPD pathogenesis. A beneficial bacterium Parabacteroides goldsteinii was isolated and shown to ameliorate COPD, with its derived active component having anti-inflammatory effects and ameliorating COPD through inhibition of lung inflammation and regulation of host metabolism.
Editorial Material
Multidisciplinary Sciences
Alice Bertocchi, Fiona Powrie
Summary: Abnormalities in gut bacteria can lead to hard-to-treat illnesses like inflammatory bowel diseases. Targeting bacteria with viruses shows promise in addressing these conditions.
Review
Immunology
Jia-Rui Zheng, Zi-Long Wang, Bo Feng
Summary: Hepatitis B virus infection causes indirect damage to hepatocytes through the immune system. The exhaustion of virus-specific immune cells and immune suppression by virus antigens contribute to the chronicity of the infection. Functional cure can be achieved by restoring the specific immune function, providing a theoretical basis for complete cure of hepatitis B.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Immunology
Shir Eliachar, Grace Ann Snyder, Shany Klara Barkan, Shani Talice, Aner Otolenghi, Adrian Jaimes-Becerra, Ton Sharoni, Eliya Sultan, Uzi Hadad, Oren Levy, Yehu Moran, Orly Gershoni-Yahalom, Nikki Traylor-Knowles, Benyamin Rosental
Summary: Climate change-induced heat stress leads to increased coral bleaching events. This study explored the immune response during heat stress using two sea anemone models. The results showed enhanced immune cell activity during heat stress, which was not influenced by the presence of algal symbionts.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
Matthieu Paiola, Dionysia Dimitrakopoulou, Martin S. Pavelka Jr, Jacques Robert
Summary: Mycobacterial infections are a major concern for both humans and vertebrates in aquatic and terrestrial environments. There are common features in the interactions between non-tuberculous mycobacteria and endo-and ectothermic animals, similar to those observed in Mycobacterium tuberculosis infections. The detection of non-tuberculous mycobacteria in amphibians is not only economically damaging but also poses a growing threat to human health.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2023)
Review
Immunology
David P. Maison, Youping Deng, Mariana Gerschenson
Summary: The SARS-CoV-2 pandemic and COVID-19 disease have had a global impact, sparking a significant surge in research. To evaluate future approaches, understanding the host immune response and viral antagonism is crucial. This review summarizes current knowledge on SARS-CoV-2, focusing on the viral genome, replication cycle, host immune activation, response, signaling, and antagonism. Efforts should be directed towards current research to develop treatments and prepare for future outbreaks.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Immunology
Tianyu Zhou, Wenzhou Xu, Qiqi Wang, Cong Jiang, Hongyan Li, Yang Chao, Yue Sun, A. Lan
Summary: Periodontitis and inflammatory bowel diseases (IBD) are gastrointestinal tract inflammatory diseases with common features of microbial-induced ecological dysregulation and immune inflammatory response. The close relationship between periodontitis and IBD indicates an Oral-Gut axis, where periodontitis patients have higher prevalence of IBD and IBD patients have higher prevalence and severity of periodontitis. The interconnection between the two involves pathogenic bacteria colonization in the gut, immune dysregulation, and alteration of oral microbiota, with Th17 cell responses and pro-inflammatory factors playing crucial roles.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Review
Allergy
Marcin Kurowski, Sven Seys, Matteo Bonini, Stefano Del Giacco, Luis Delgado, Zuzana Diamant, Marek L. Kowalski, Andre Moreira, Maia Rukhadze, Mariana Couto
Summary: This review examines the impact of exercise on infection susceptibility and highlights key areas for future research. Different intensities of exercise have varying effects on immune health and susceptibility to infections, particularly respiratory infections. Promising areas for further investigation include immunological characterization, efficacy of interventions, and the influence of exercise loads on infection symptoms.
Article
Immunology
Barbara Poniedzialek, Ewelina Hallmann, Dominika Sikora, Karol Szymanski, Katarzyna Kondratiuk, Jakub Zurawski, Piotr Rzymski, Lidia Brydak
Summary: Evidence suggests that vaccination against seasonal influenza can enhance innate immune responses to COVID-19 and reduce disease severity. This study aimed to compare humoral responses to SARS-CoV-2 in non-hospitalized, COVID-19 unvaccinated patients and mild COVID-19 convalescent patients who were and were not vaccinated against influenza. The results showed that influenza-vaccinated patients had higher levels of antibodies against nucleocapsid and receptor binding domain compared to non-vaccinated patients.
Article
Medicine, Research & Experimental
Elizabeth S. Levy, Ryan Chang, Colin R. Zamecnik, Miqdad O. Dhariwala, Lawrence Fong, Tejal A. Desai
Summary: Combining immune agonists and a melanoma-specific peptide in nanoparticles significantly enhances activation of antigen-presenting cells and promotes the development and response of melanoma-sensitized T cells, leading to suppression of tumor growth and reduction of tumor burden in both solid and metastatic tumor models. This biomaterial-based approach provides insights into stimulating multiple activation pathways for promoting tumor regression and delivering combination immunotherapies effectively and safely for cancer treatment.
MOLECULAR PHARMACEUTICS
(2021)
Article
Immunology
Liang Ye, Bo Jiang, Jun Deng, Jing Du, Wen Xiong, Youfei Guan, Zhongyang Wen, Kunzhao Huang, Zhong Huang
JOURNAL OF IMMUNOLOGY
(2015)
Article
Medicine, Research & Experimental
Bingni Chen, Kunzhao Huang, Liang Ye, Yanqun Li, Jiawei Zhang, Jinshun Zhang, Xinmin Fan, Xiaokai Liu, Li Li, Jinxia Sun, Jing Du, Zhong Huang
JOURNAL OF TRANSLATIONAL MEDICINE
(2015)
Article
Oncology
Si Chen, Bingni Chen, Zhongyang Wen, Zhong Huang, Liang Ye
Article
Biology
Jonas Klinkhammer, Daniel Schnepf, Liang Ye, Marilena Schwaderlapp, Hans Henrik Gad, Rune Hartmann, Dominique Garcin, Tanel Mahlakoiv, Peter Staeheli
Article
Pharmacology & Pharmacy
Annasaheb Kolpe, Bert Schepens, Liang Ye, Peter Staeheli, Xavier Saelens
ANTIVIRAL RESEARCH
(2018)
Article
Immunology
Valentina Bernasconi, Beatrice Bernocchi, Liang Ye, Minh Quan Le, Ajibola Omokanye, Rodolphe Carpentier, Karin Schon, Xavier Saelens, Peter Staeheli, Didier Betbeder, Nils Lycke
FRONTIERS IN IMMUNOLOGY
(2018)
Article
Immunology
Liang Ye, Daniel Schnepf, Jan Becker, Karolina Ebert, Yakup Tanriver, Valentina Bernasconi, Hans Henrik Gad, Rune Hartmann, Nils Lycke, Peter Staeheli
Article
Immunology
Yanmei Ma, Zhihua Yin, Li Li, Bingni Chen, Hanying Dai, Dandan Wu, Junxiao Cong, Liang Ye, Chenghui Liao, Lingyun Li, Zhizhong Ye, Zhong Huang
Summary: Food antigens and mucosal barrier injury act synergistically to cause intestinal inflammation; the study suggests that CII-induced enteritis is associated with higher levels of Th1, TLR2 and TLR4, and lower levels of Th2.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Immunology
Liang Ye, Daniel Schnepf, Annette Ohnemus, Li Ching Ong, Hans Henrik Gad, Rune Hartmann, Nils Lycke, Peter Staeheli
Summary: The study demonstrates the importance of IFN-λ and TSLP in vaccine-induced antiviral immunity by improving antigen-specific antibody responses and enhancing resistance to influenza virus challenge. TSLP receptor deficiency negatively impacts vaccine-induced antiviral immunity by impairing dendritic cell migration and follicular helper T cell/germinal center B cell responses.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Virology
Liang Ye, Annette Ohnemus, Li Ching Ong, Hans Henrik Gad, Rune Hartmann, Nils Lycke, Peter Staeheli
JOURNAL OF VIROLOGY
(2019)
Review
Immunology
Liang Ye, Daniel Schnepf, Peter Staeheli
NATURE REVIEWS IMMUNOLOGY
(2019)
Meeting Abstract
Biochemistry & Molecular Biology
Peter Staeheli, Liang Ye, Daniel Schnepf, Jan Becker, Karolina Ebert, Valentina Bernasconi, Hans A. Gad, Yakup Tanriver, Rune Hartmann, Nils Lycke
Meeting Abstract
Biochemistry & Molecular Biology
P. Staehelil, J. Klinkhammer, D. Schnepf, L. Ye, M. Schwaderlapp, D. Garcin, T. Malakoiv
Article
Medicine, Research & Experimental
Jing Du, Jian Zhang, Dexue Zou, Liang Ye, G. George Chen, Chao Yang
CLINICAL AND EXPERIMENTAL MEDICINE
(2015)
