Dual protection of hydroxytyrosol, an olive oil polyphenol, against oxidative damage in PC12 cells

Xanthohumol, a Polyphenol Chalcone Present in Hops, Activating Nrf2 Enzymes To Confer Protection against Oxidative Damage in PC12 Cells

(2015) Juan Yao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Selective Selenol Fluorescent Probes: Design, Synthesis, Structural Determinants, and Biological Applications

(2015) Baoxin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Shikonin targets cytosolic thioredoxin reductase to induce ROS-mediated apoptosis in human promyelocytic leukemia HL-60 cells

(2014) Dongzhu Duan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase

(2014) Dongzhu Duan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of the Phase II Enzymes for Neuroprotection by Ginger Active Constituent 6-Dehydrogingerdione in PC12 Cells

(2014) Juan Yao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dithiaarsanes Induce Oxidative Stress-Mediated Apoptosis in HL-60 Cells by Selectively Targeting Thioredoxin Reductase

(2014) Yaping Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation

(2014) Lijuan Sun et al.   Food & Function

Bioactivity and phenolic composition from natural fermented table olives

(2014) Ricardo Malheiro et al.   Food & Function

The effect of hydroxytyrosol and its nitroderivatives on catechol-O-methyl transferase activity in rat striatal tissue

(2014) Elena Gallardo et al.   RSC Advances

Synthesis and molecular modeling study of Cu(II) complexes derived from 2-(diphenylmethylene)hydrazinecarbothioamide derivatives with cholinesterase inhibitory activities

(2013) Yi Chen Chan et al.   CHINESE CHEMICAL LETTERS

Thiol/disulfide redox states in signaling and sensing

(2013) Young-Mi Go et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

(2013) Takumi Satoh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Keap Calm, and Carry on Covalently

(2013) Anthony J. Wilson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Highly Selective Off–On Fluorescent Probe for Imaging Thioredoxin Reductase in Living Cells

(2013) Liangwei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Health effects of olive oil polyphenols: Recent advances and possibilities for the use of health claims

(2013) Sandra Martín-Peláez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells

(2013) Adele Chimento et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Toward clinical application of the Keap1–Nrf2 pathway

(2013) Takafumi Suzuki et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents

(2012) Sadagopan Magesh et al.   MEDICINAL RESEARCH REVIEWS

Effects of natural antioxidants in neurodegenerative disease

(2012) Sonia Luz Albarracin et al.   NUTRITIONAL NEUROSCIENCE

A selective and sensitive fluorescence probe for imaging endogenous zinc in living cells

(2012) Liangwei Zhang et al.   TETRAHEDRON

Curcumin targeting the thioredoxin system elevates oxidative stress in HeLa cells

(2012) Wenqing Cai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tyrosol and Hydroxytyrosol Two Main Components of Olive Oil, Protect N2a Cells Against Amyloid-β-Induced Toxicity. Involvement of the NF-κB Signaling

(2011) C. St-Laurent-Thibault et al.   Current Alzheimer Research

Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK–FOXO3a pathway

(2011) Houda Zrelli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Small molecule inhibitors of mammalian thioredoxin reductase

(2011) Wenqing Cai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydroxytyrosol Induces Proliferation and Cytoprotection against Oxidative Injury in Vascular Endothelial Cells: Role of Nrf2 Activation and HO-1 Induction

(2011) Houda Zrelli et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Protective Effects of Resveratrol and its Analogues against Free Radical-Induced Oxidative Hemolysis of Red Blood Cells†

(2010) Jian-Guo Fang et al.   CHINESE JOURNAL OF CHEMISTRY

Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

(2010) Lu Zhu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells

(2010) María Angeles Martín et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hydroxytyrosol: from laboratory investigations to future clinical trials

(2010) Sergio Granados-Principal et al.   NUTRITION REVIEWS

Cytoprotective effects of olive mill wastewater extract and its main constituent hydroxytyrosol in PC12 cells

(2010) Sebastian Schaffer et al.   PHARMACOLOGICAL RESEARCH

Thiol Chemistry in Peroxidase Catalysis and Redox Signaling

(2008) Alberto Bindoli et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia–reoxygenation

(2008) José Antonio González-Correa et al.   NEUROSCIENCE LETTERS

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY