Role of kappa-opioid receptors in stress and anxiety-related behavior

The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration

(2013) Shainnel O Eans et al.   BRITISH JOURNAL OF PHARMACOLOGY

Recent developments in animal models of drug relapse

(2013) Nathan J Marchant et al.   CURRENT OPINION IN NEUROBIOLOGY

Behavioral, biological, and chemical perspectives on targeting CRF1 receptor antagonists to treat alcoholism

(2013) Eric P. Zorrilla et al.   DRUG AND ALCOHOL DEPENDENCE

Development of κ Opioid Receptor Antagonists

(2013) F. Ivy Carroll et al.   JOURNAL OF MEDICINAL CHEMISTRY

Kappa Opioid Receptors Regulate Stress-Induced Cocaine Seeking and Synaptic Plasticity

(2013) Nicholas M. Graziane et al.   NEURON

Ablation of Kappa-Opioid Receptors from Brain Dopamine Neurons has Anxiolytic-Like Effects and Enhances Cocaine-Induced Plasticity

(2013) Ashlee Van't Veer et al.   NEUROPSYCHOPHARMACOLOGY

Prefrontal Cortical Kappa-Opioid Receptor Modulation of Local Neurotransmission and Conditioned Place Aversion

(2013) Hugo A Tejeda et al.   NEUROPSYCHOPHARMACOLOGY

Roles of Nucleus Accumbens CREB and Dynorphin in Dysregulation of Motivation

(2013) J. W. Muschamp et al.   Cold Spring Harbor Perspectives in Medicine

Presynaptic Inhibition of Gamma-Aminobutyric Acid Release in the Bed Nucleus of the Stria Terminalis by Kappa Opioid Receptor Signaling

(2012) Chia Li et al.   BIOLOGICAL PSYCHIATRY

Opioid receptor expression in human brain and peripheral tissues using absolute quantitative real-time RT-PCR

(2012) Jinsong Peng et al.   DRUG AND ALCOHOL DEPENDENCE

Stress-Induced Activation of the Dynorphin/ -Opioid Receptor System in the Amygdala Potentiates Nicotine Conditioned Place Preference

(2012) J. S. Smith et al.   JOURNAL OF NEUROSCIENCE

Stress Produces Aversion and Potentiates Cocaine Reward by Releasing Endogenous Dynorphins in the Ventral Striatum to Locally Stimulate Serotonin Reuptake

(2012) A. G. Schindler et al.   JOURNAL OF NEUROSCIENCE

Repeated Stress Dysregulates  -Opioid Receptor Signaling in the Dorsal Raphe through a p38  MAPK-Dependent Mechanism

(2012) J. C. Lemos et al.   JOURNAL OF NEUROSCIENCE

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

(2012) Dipesh Chaudhury et al.   NATURE

Neurobiology of resilience

(2012) Scott J Russo et al.   NATURE NEUROSCIENCE

Corticotropin-Releasing Factor (CRF)-Induced Disruption of Attention in Rats Is Blocked by the κ-Opioid Receptor Antagonist JDTic

(2012) Ashlee Van'T Veer et al.   NEUROPSYCHOPHARMACOLOGY

Kappa opioid regulation of anxiety-like behavior during acute ethanol withdrawal

(2012) Glenn R. Valdez et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effect of food restriction on cocaine locomotor sensitization in Sprague–Dawley rats

(2012) Craig P. Allen et al.   PSYCHOPHARMACOLOGY

Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice

(2012) K. J. Jackson et al.   PSYCHOPHARMACOLOGY

Stress modulation of cognitive and affective processes

(2012) Serge Campeau et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Kappa Opioid Receptor Signaling in the Basolateral Amygdala Regulates Conditioned Fear and Anxiety in Rats

(2011) Allison T. Knoll et al.   BIOLOGICAL PSYCHIATRY

Repeated Exposure to the κ-Opioid Receptor Agonist Salvinorin A Modulates Extracellular Signal-Regulated Kinase and Reward Sensitivity

(2011) David N. Potter et al.   BIOLOGICAL PSYCHIATRY

Early detection and intervention for attention-deficit/hyperactivity disorder

(2011) Edmund JS Sonuga-Barke et al.   Expert Review of Neurotherapeutics

Activation of CREB in the Nucleus Accumbens Shell Produces Anhedonia and Resistance to Extinction of Fear in Rats

(2011) J. W. Muschamp et al.   JOURNAL OF NEUROSCIENCE

Aversive Stimuli Alter Ventral Tegmental Area Dopamine Neuron Activity via a Common Action in the Ventral Hippocampus

(2011) O. Valenti et al.   JOURNAL OF NEUROSCIENCE

Selective p38α MAPK Deletion in Serotonergic Neurons Produces Stress Resilience in Models of Depression and Addiction

(2011) Michael R. Bruchas et al.   NEURON

Stress modulation of drug self-administration: Implications for addiction comorbidity with post-traumatic stress disorder

(2011) Marian L. Logrip et al.   NEUROPHARMACOLOGY

Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats

(2011) Elena Chartoff et al.   NEUROPHARMACOLOGY

Decreased response to social defeat stress in μ-opioid-receptor knockout mice

(2011) Hiroshi Komatsu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Behavioural consequences of two chronic psychosocial stress paradigms: Anxiety without depression

(2011) David A. Slattery et al.   PSYCHONEUROENDOCRINOLOGY

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder

(2011) Amy L. Mahan et al.   TRENDS IN NEUROSCIENCES

Progress in corticotropin-releasing factor-1 antagonist development

(2010) Eric P. Zorrilla et al.   DRUG DISCOVERY TODAY

Behavioral Stress May Increase the Rewarding Valence of Cocaine-Associated Cues Through a Dynorphin/κ-Opioid Receptor-Mediated Mechanism without Affecting Associative Learning or Memory Retrieval Mechanisms

(2010) Abigail G Schindler et al.   NEUROPSYCHOPHARMACOLOGY

CRF1-R Activation of the Dynorphin/Kappa Opioid System in the Mouse Basolateral Amygdala Mediates Anxiety-Like Behavior

(2010) Michael R. Bruchas et al.   PLoS One

Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-Hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats

(2010) Patrick M. Beardsley et al.   PSYCHOPHARMACOLOGY

The role of the dynorphin–κ opioid system in the reinforcing effects of drugs of abuse

(2010) Sunmee Wee et al.   PSYCHOPHARMACOLOGY

Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse

(2010) K. J. Jackson et al.   PSYCHOPHARMACOLOGY

Comparison of the kappa-opioid receptor antagonist DIPPA in tests of anxiety-like behavior between Wistar Kyoto and Sprague Dawley rats

(2010) Gregory V. Carr et al.   PSYCHOPHARMACOLOGY

Kinase cascades and ligand-directed signaling at the kappa opioid receptor

(2010) Michael R. Bruchas et al.   PSYCHOPHARMACOLOGY

Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration

(2010) Robin E. Sperling et al.   PSYCHOPHARMACOLOGY

Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats

(2009) Thomas N. Greenwell et al.   ADDICTION BIOLOGY

Role of CRF Receptor Signaling in Stress Vulnerability, Anxiety, and Depression

(2009) Richard L. Hauger et al.   Annals of the New York Academy of Sciences

Dynorphin, stress, and depression

(2009) Allison T. Knoll et al.   BRAIN RESEARCH

kappa-Opioid receptor signaling and brain reward function

(2009) Adrie W. Bruijnzeel   BRAIN RESEARCH REVIEWS

Altered Sensitivity to Rewarding and Aversive Drugs in Mice with Inducible Disruption of cAMP Response Element-Binding Protein Function within the Nucleus Accumbens

(2009) J. A. DiNieri et al.   JOURNAL OF NEUROSCIENCE

Endogenous   Opioid Activation Mediates Stress-Induced Deficits in Learning and Memory

(2009) A. N. Carey et al.   JOURNAL OF NEUROSCIENCE

Salvinorin A exerts opposite presynaptic controls on neurotransmitter exocytosis from mouse brain nerve terminals

(2009) Massimo Grilli et al.   NEUROPHARMACOLOGY

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Antidepressant-Like Effects of κ-Opioid Receptor Antagonists in Wistar Kyoto Rats

(2009) Gregory V Carr et al.   NEUROPSYCHOPHARMACOLOGY

30 years of dynorphins — New insights on their functions in neuropsychiatric diseases

(2009) Christoph Schwarzer   PHARMACOLOGY & THERAPEUTICS

Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

(2009) Benjamin B. Land et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zyklophin, a systemically active selective kappa opioid receptor peptide antagonist with short duration of action

(2009) J. V. Aldrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Kappa-Opioid Agonist U69,593 Blocks Cocaine-Induced Enhancement of Brain Stimulation Reward

(2008) Hilarie C. Tomasiewicz et al.   BIOLOGICAL PSYCHIATRY

The Dysphoric Component of Stress Is Encoded by Activation of the Dynorphin  -Opioid System

(2008) B. B. Land et al.   JOURNAL OF NEUROSCIENCE

Midbrain Dopamine Neurons: Projection Target Determines Action Potential Duration and Dopamine D2 Receptor Inhibition

(2008) E. B. Margolis et al.   JOURNAL OF NEUROSCIENCE

Biological substrates of reward and aversion: A nucleus accumbens activity hypothesis

(2008) William A. Carlezon et al.   NEUROPHARMACOLOGY

κ-Opioid System Regulates the Long-Lasting Behavioral Adaptations Induced by Early-Life Exposure to Methylphenidate

(2008) Matthew D Wiley et al.   NEUROPSYCHOPHARMACOLOGY

Prodynorphin-Derived Peptides Are Critical Modulators of Anxiety and Regulate Neurochemistry and Corticosterone

(2008) Walter Wittmann et al.   NEUROPSYCHOPHARMACOLOGY

Effects of maternal separation on hypothalamic–pituitary–adrenal responses, cognition and vulnerability to stress in adult female rats

(2008) B. Aisa et al.   NEUROSCIENCE

Social stress, therapeutics and drug abuse: Preclinical models of escalated and depressed intake

(2008) K MICZEK et al.   PHARMACOLOGY & THERAPEUTICS

Control of hormonal stress reactivity by the endogenous opioid system

(2008) Andras Bilkei-Gorzo et al.   PSYCHONEUROENDOCRINOLOGY

Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic–pituitary–adrenal axis in monkeys

(2008) John E. Pascoe et al.   PSYCHONEUROENDOCRINOLOGY

Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system

(2008) Van A. Redila et al.   PSYCHOPHARMACOLOGY

Effects of chronic and acute stressors and CRF on depression-like behavior in mice

(2007) Artur H. Swiergiel et al.   BEHAVIOURAL BRAIN RESEARCH