Article
Biochemistry & Molecular Biology
Xiaowan Feng, Hui Zhang, Phoency F. H. Lai, Zhiqiang Xiong, Lianzhong Ai
Summary: A pyruvated exopolysaccharide named LPE-1 was isolated and characterized from the fermentation broth of Lactobacillus plantarum AR307. LPE-1 was found to contain Galp and Glcp at a molar ratio of 2:1, with a molecular weight of 605 kDa. The presence of pyruvate group in LPE-1 plays a significant role in improving the viscosity and plasticity of dairy products.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Owen T. Tuck, Eric T. Sletten, Jose Danglad-Flores, Peter H. Seeberger
Summary: Research shows that glycosyl donor activation reactions at different temperatures exhibit diversity, and can avoid deleterious side reactions and reduce the amount of building blocks required by using an activation temperature. This finding contributes to optimizing the usage of glycosyl donors and improving the efficiency of oligosaccharide synthesis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Food Science & Technology
Elif Tasdelen, Omer Simsek
Summary: Using EPS-producing L. plantarum strains improved the viscosity and color stability of tarhana soups, indicating their potential as starter cultures for enhancing the technological and health aspects of tarhana.
Article
Biochemistry & Molecular Biology
Shudong Peng, Chaoqun Guo, Hongchang Cui, Zhi Duan
Summary: The purpose of this study was to isolate a novel strain of Lactiplantibacillus plantarum with probiotic functions to combat Streptococcus pneumoniae. The strain, named VHProbi P06, exhibited strong antibacterial activity, adhesion to 5-8F cells, and inhibition of S. pneumoniae colonization in the respiratory tract. Genome analysis revealed several gene clusters related to adhesion, exopolysaccharide biosynthesis, and phage regions. This study provides a theoretical basis for the application of VHProbi P06 in the upper respiratory tract to resist pathogenic bacteria.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Min Zhang, Tiantian Lai, Mengke Yao, Man Zhang, Zhennai Yang
Summary: The study found interactions between EPS produced by LAB and casein, resulting in improved physical properties and bioactivities of their complex. These interaction mechanisms are important for enhancing the functionality of fermented dairy products.
Article
Cell Biology
Jaehoon Lee, Sangkyu Park, Naeun Oh, Jaehyun Park, Mijin Kwon, Jeongmin Seo, Sangho Roh
Summary: The study found that EPS in L-14 extract inhibits adipogenesis through TLR2 and AMPK signaling pathways, improving obesity and obesity-related diseases in vivo.
CELL PROLIFERATION
(2021)
Article
Food Science & Technology
Mengke Yao, Min Zhang, Tiantian Lai, Zhennai Yang
Summary: In this study, exopolysaccharide (EPS) produced by Lactiplantibacillus plantarum NMGL2 from traditional fermented dairy cheese was purified and characterized. The purified EPS had a low molecular weight and high degradation temperature, and exhibited a specific microstructure. Furthermore, the EPS demonstrated regulatory effects on the gut microbiota and showed potential applications in the food and health care industry.
Article
Biochemistry & Molecular Biology
Yinglong Song, Mengying Sun, Guangqing Mu, Yanfeng Tuo
Summary: This study found that Lactiplantibacillus plantarum Y12 exopolysaccharide (L-EPS) has significant regulatory effects on gene expression in Shigella flexneri, inhibiting biofilm formation. The inhibitory effect is achieved through the regulation of specific genes and disruption of the spatial structure.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Qi'an Wang, Bensheng Jiang, Min Wei, Yao He, Yujie Wang, Qimeng Zhang, Hua Wei, Xueying Tao
Summary: Exopolysaccharide (EPS-09) from L. plantarum WLPL09 was found to have antitumor effects in B16F10 melanoma bearing mice. It inhibited tumor growth, promoted lymphocyte proliferation, increased the number of T cells and cytokine content in tumor tissue. EPS-09 also regulated the composition of intestinal microbiota. These findings suggest that EPS-09 induces tumor cell apoptosis, inhibits tumor angiogenesis, improves immunity, and exhibits positive antitumor activity against melanoma.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Food Science & Technology
Junyong Wang, Jing Zhang, Henan Guo, Qiang Cheng, Zaheer Abbas, Yucui Tong, Tiantian Yang, Yichen Zhou, Haosen Zhang, Xubiao Wei, Dayong Si, Rijun Zhang
Summary: The yield of exopolysaccharide (EPS) from Lactobacillus plantarum R301 was optimized using a single-factor experiment and response surface methodology (RSM), resulting in a 0.85-fold increase. The significant factors affecting EPS production were determined to be MgSO4 concentration, initial pH, and inoculation size. The EPS demonstrated strong antioxidant and anti-inflammatory activities, making it a potential multifunctional food additive in the food industry.
Article
Microbiology
Eman H. Zaghloul, Mohamed I. A. Ibrahim
Summary: This study reports the wound healing activity and probiotic properties of an exopolysaccharide (EPS) produced by a marine Lactiplantibacillus plantarum strain, EI6. EI6-EPS demonstrated promising antimicrobial activity, resistance to stomach pH and bile salt concentration, and high EPS production. Chemical analysis revealed the composition of EI6-EPS, with five monosaccharides linked together by alpha- and beta-glycosidic linkages. Furthermore, EI6-EPS was found to promote proliferation and migration of human skin fibroblasts (HSF).
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Ji Wang, Meihe Li, Yawen Gao, Hongmei Li, Li Fang, Chunlei Liu, Xiaoting Liu, Weihong Min
Summary: This study investigated the effects of EPS103 on the intestinal immune response, oxidative stress, intestinal mucosal barrier, and microbial community in immunosuppressed mice. The results showed that EPS103 enhanced the intestinal immune response, protected against oxidative stress, improved the intestinal barrier function, and modulated the gut microbiota in mice.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Food Science & Technology
Yuan Qi, Danyang Wang, Li Fang, Xiaoting Liu, Chunlei Liu, Fanrui Zhao, Dan Wu, Xiyan Wang, Ji Wang, Weihong Min
Summary: This study demonstrated that the exopolysaccharide (EPS103) derived from Lactiplantibacillus plantarum JLAU103 has hypoglycemic, hypolipidemic, and neuroprotective effects in a type 2 diabetes mouse model. EPS103 regulates glucose metabolism pathways, inhibits inflammation, and shows potential as a therapeutic agent for the treatment of type 2 diabetes.
Article
Biochemistry & Molecular Biology
Mariyappan Kowsalya, Thangavel Velmurugan, R. Mythili, Woong Kim, Kattakgounder Govindaraj Sudha, Saheb Ali, Balakrishnan Kalpana, Srinivasan Ramalingam, Mohan Prasanna Rajeshkumar
Summary: This study characterized the exopolysaccharides (EPS) produced by probiotic bacteria Lactiplantibacillus plantarum PRK7 and L. plantarum PRK11 using various analytical methods. The EPS-7 and EPS-11 exhibited good structural characteristics and showed antioxidant, emulsion, and antibiofilm activities, making them suitable for applications in the food and pharmaceutical industry.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Rentao Zhang, Zhongkun Zhou, Yunhao Ma, Kangjia Du, Mengze Sun, Hao Zhang, Hongyuan Tu, Xinrong Jiang, Juan Lu, Lixue Tu, Yuqing Niu, Peng Chen
Summary: This study investigated the effects of EPS from Lactiplantibacillus plantarum YT013 on gastric cancer cells. The results showed that EPS had the most significant inhibitory effect on AGS cells at a concentration of 1000μg/mL, followed by SGC-7901, PANC-1, and HCT116 cells, and had less inhibition on HepG2 cells. Cell cycle analysis demonstrated that EPS prevented AGS cells from transitioning from the S phase to the G(2)/M phase. Furthermore, flow cytometry results indicated that EPS promoted apoptosis in a concentration-dependent manner, possibly through the endogenous mitochondrial apoptotic pathway. The safety and effectiveness of lyophilized powder, cell-free culture supernatant, and EPS from Lactiplantibacillus plantarum YT013 were evaluated, and the results suggested that these components could serve as a basis for the development of natural anticancer active drugs.
FERMENTATION-BASEL
(2023)
Article
Environmental Sciences
Anand Babu Perumal, Reshma B. Nambiar, Periyar Selvam Sellamuthu, Emmanuel Rotimi Sadiku, Xiaoli Li, Yong He
Summary: Areca nut husk fibers were used to extract cellulose nanocrystals (CNCs) for the reinforcement of polyvinyl alcohol (PVA) and chitosan (CS) films. The CNC showed good thermal stability, enhanced the tensile strength of the bionanocomposite film, and exhibited antimicrobial activity against foodborne pathogens and postharvest pathogenic fungi, suggesting its potential for food packaging applications.
Review
Food Science & Technology
C. Drishya, K. S. Yoha, Anand Babu Perumal, Jeyan A. Moses, C. Anandharamakrishnan, V. M. Balasubramaniam
Summary: Nonthermal technologies can effectively remove or reduce levels of mycotoxins in food products without compromising food quality. These technologies use lethal agents to degrade mycotoxins, enabling food processors to deliver high-quality mycotoxin-free food products.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Physics, Condensed Matter
Gbolahan Joseph Adekoya, Oluwasegun Chijioke Adekoya, Emmanuel Rotimi Sadiku, Yskandar Hamam, Suprakas Sinha Ray
Summary: In this study, the interaction between borophene nanoplatelets (BNPs) and graphene nanoplatelets (GNPs) on the mechanical properties of Poly(3,4-ethylene dioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) film was investigated using a finite element method (FEM). The results showed that the elastic moduli of the nanocomposites improved by 9.6% and 10.2%, respectively. This research provides valuable insights into enhancing the mechanical stability of PEDOT:PSS electrodes.
Article
Energy & Fuels
B. Mahanta, A. Saikia, P. Saikia, J. Jayaramudu, S. Periyar Selvam, A. Varada Rajulu, E. Rotimi Sadiku
Summary: The presence of oxides generated during coal combustion affects the ash fusion temperature (AFT). Coals from Meghalaya, particularly those with higher amounts of acidic components and lower amounts of basic components, have lower slagging and fouling indices and increased AFT. Statistical analysis confirms the influence of various fluxing agents on the AFT of the coal samples.
INTERNATIONAL JOURNAL OF COAL PREPARATION AND UTILIZATION
(2023)
Review
Chemistry, Physical
V. Dharini, S. Periyar Selvam, J. Jayaramudu, R. Sadiku Emmanuel
Summary: This study explores the importance of using nanoclay in enhancing biocomposite films and its impact on food packaging materials. Despite the excellent mechanical and gas barrier properties of nanoclays, further understanding of their toxicity profile is needed.
APPLIED CLAY SCIENCE
(2022)
Article
Chemistry, Analytical
Xuelun Luo, Mostafa Gouda, Anand Babu Perumal, Zhenxiong Huang, Lei Lin, Yu Tang, Alireza Sanaeifar, Yong He, Xiaoli Li, Chunwang Dong
Summary: This study presented a rapid method based on surface-enhanced Raman spectroscopy (SERS) technology and chemometrics to monitor the quality changes of black tea during fermentation. By combining SERS data with a one-dimensional convolutional neural network (1D-CNN), the content of catechin (C) and epigallocatechin gallate (EGCG) in black tea can be accurately predicted, enabling the determination of the optimal fermentation stage and improvement of tea quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Crystallography
Azunna Agwo Eze, Emmanuel Rotimi Sadiku, Williams Kehinde Kupolati, Jacques Snyman, Julius Musyoka Ndambuki, Idowu David Ibrahim
Summary: In this study, a near-equiatomic multi-principal element alloy with nano- and micron-sized Nb particles was synthesized using spark plasma sintering (SPS) technique. The alloys with nano-sized Nb particles showed faster sintering, lower wear rate, and dendritic microstructure with nano-segregations. Cu-NbTiB2C alloy sintered at 650°C exhibited the highest microhardness, while CuNbTiB2C alloy with micron-sized Nb particles sintered at 700°C showed the best corrosion resistance in a sulfuric acid environment. These novel materials have great potential for aerospace applications.
Review
Polymer Science
Oluwaseye Samson Adedoja, Emmanuel Rotimi Sadiku, Yskandar Hamam
Summary: Energy storage is a challenge in the energy sector, but supercapacitors have revolutionized the industry with their high energy capacity, reliable supply, and extended lifetime. Scientists have conducted investigations to improve their development and explore potential applications. This review provides an up-to-date investigation of supercapacitor technologies, including components, operating techniques, potential applications, technical difficulties, benefits, and drawbacks.
Article
Polymer Science
Karabo Innocent Matumba, Mpho Phillip Motloung, Vincent Ojijo, Suprakas Sinha Ray, Emmanuel Rotimi Sadiku
Summary: This study investigated the effect of Joncryl concentration on the properties of PLA/PCL and PLA/PEG blends. The addition of Joncryl influenced the properties of both blends, with reduced droplet size and improved compatibility observed in PLA/PCL blends, and the presence of a co-continuous morphology in PLA/PEG blends at certain Joncryl loadings. Joncryl addition also decreased the crystallinity of PCL and PEG in the blends. The thermal stabilities and mechanical properties of the blends were shown to be dependent on the Joncryl concentration.
Article
Agricultural Engineering
Xiaoli Li, Yulun Dong, Kai Chen, Anand Babu Perumal, Zhihao Zhan, Mostafa Gouda, Yong He
Summary: This study investigated the accumulation of lipid and metabolic fluxes in Tetradesmus obliquus under nitrogen deficiency stress using a 13C isotope tracer. The results showed that there was an increase in carbon flux from CO2 into lipid synthesis, leading to the accumulation of palmitic acid, linoleic acid, and oleic acid. It was also observed that under nitrogen deficiency stress, T. obliquus had higher flux in the PPP and glycolysis pathway, which could provide more NADPH and substrate acetyl-CoA for fatty acid synthesis.
BIORESOURCE TECHNOLOGY
(2023)
Article
Polymer Science
Senthamil Selvi Poongavanam, Vishnupriya Subramaniyan, Periyar Selvam Sellamuthu, Jayaramudu Jarugala, Emmanuel Rotimi Sadiku
Summary: In this study, it was found that using bio-nanocomposite films containing 8% cellulose nanocrystals can extend the shelf life of Sapota fruits. The combination of these films with ajwain essential oil and oregano essential oil showed the best results, serving as suitable alternatives to commercial fungicides.
Article
Materials Science, Multidisciplinary
Senthamil Selvi Poongavanam, Vishnupriya Subramaniyan, Abhishek Biswal Rajendra, Periyar Selvam Sellamuthu, Jayaramudu Jarugala, Emmanuel Rotimi Sadiku
Summary: The effect of three different treatments on sapota fruits was compared in this study. The results showed that AV 100%+5 mu L AO and AV 100%+5 mu L OO treatments could prolong the shelf life and preserve the quality of sapota fruits. Therefore, using these treatments for sapota fruits could be a promising alternative to commercial fungicides.
Article
Chemistry, Multidisciplinary
Chandrasekaran Karthikeyan, Natarajan Sisubalan, Kokkarachedu Varaprasad, Radhamanohar Aepuru, Murali M. Yallapu, Mangalaraja Ramalinga Viswanathan, Umaralikhan, Rotimi Sadiku
Summary: This study synthesized Cs/Ni/NiO hybrid nanoparticles (HNPs) using an inexpensive chemical synthesis method and characterized their properties. The HNPs exhibited significant bactericidal and cytotoxic effects against pathogenic bacteria and carcinoma cells, while showing good biocompatibility towards normal cells.
NEW JOURNAL OF CHEMISTRY
(2022)
Review
Materials Science, Biomaterials
Jagan Mohan Dodda, Tomas Remis, Sadiku Rotimi, Yi-Cheun Yeh
Summary: This article provides an overview of PLGA-based conjugates in cancer research, focusing on their roles as targeted drug carriers and sustained drug controllers. The preparation and drug encapsulation of PLGA nanoparticles and FA-PEG-PLGA conjugates are discussed, with emphasis on the associated chemistries and biocompatibility. This review offers a deeper understanding of PLGA-conjugated materials for successful material design and biomedical applications.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
