Targeting chronic lymphocytic leukemia cells with a humanized monoclonal antibody specific for CD44

Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells

(2012) Emma Hamilton et al.   BRITISH JOURNAL OF HAEMATOLOGY

Global Quantitative Phosphoproteome Analysis of Human Tumor Xenografts Treated with a CD44 Antagonist

(2012) S. Weigand et al.   CANCER RESEARCH

Evidence for a macromolecular complex in poor prognosis CLL that contains CD38, CD49d, CD44 and MMP-9

(2011) Andrea G. S. Buggins et al.   BRITISH JOURNAL OF HAEMATOLOGY

Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1

(2011) Yair Herishanu et al.   LEUKEMIA & LYMPHOMA

Evidences for correlation between the reduced VCAM-1 expression and hyaluronan synthesis during cellular senescence of human mesenchymal stem cells

(2010) Eun Mi Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The lymph node microenvironment promotes B-cell receptor signaling, NF- B activation, and tumor proliferation in chronic lymphocytic leukemia

(2010) Y. Herishanu et al.   BLOOD

Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF- B Activation and De novo Gene Transcription

(2010) A. G. S. Buggins et al.   CANCER RESEARCH

Hyaluronan in human malignancies

(2010) R.K. Sironen et al.   EXPERIMENTAL CELL RESEARCH

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL

(2010) Aneela Majid et al.   LEUKEMIA RESEARCH

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

(2009) J. A. Burger et al.   BLOOD

Bcl-2-family proteins and hematologic malignancies: history and future prospects

(2008) J. C. Reed   BLOOD

CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment

(2008) P. E. M. Patten et al.   BLOOD

 4 1 integrin and 190-kDa CD44v constitute a cell surface docking complex for gelatinase B/MMP-9 in chronic leukemic but not in normal B cells

(2008) J. Redondo-Munoz et al.   BLOOD

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

(2008) L. Z. Rassenti et al.   BLOOD

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

(2008) Tait D. Shanafelt et al.   BRITISH JOURNAL OF HAEMATOLOGY