Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells

Evidence for a macromolecular complex in poor prognosis CLL that contains CD38, CD49d, CD44 and MMP-9

(2011) Andrea G. S. Buggins et al.   BRITISH JOURNAL OF HAEMATOLOGY

Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2

(2011) C. Pepper et al.   CELL PROLIFERATION

IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells

(2011) M Coscia et al.   LEUKEMIA

A novel role of the CX3CR1/CX3CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment

(2011) E Ferretti et al.   LEUKEMIA

The functional in vitro response to CD40 ligation reflects a different clinical outcome in patients with chronic lymphocytic leukemia

(2011) C Scielzo et al.   LEUKEMIA

The lymph node microenvironment promotes B-cell receptor signaling, NF- B activation, and tumor proliferation in chronic lymphocytic leukemia

(2010) Y. Herishanu et al.   BLOOD

Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF- B Activation and De novo Gene Transcription

(2010) A. G. S. Buggins et al.   CANCER RESEARCH

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL

(2010) Aneela Majid et al.   LEUKEMIA RESEARCH

CD38/CD31, the CCL3 and CCL4 Chemokines, and CD49d/Vascular Cell Adhesion Molecule-1 Are Interchained by Sequential Events Sustaining Chronic Lymphocytic Leukemia Cell Survival

(2009) A. Zucchetto et al.   CANCER RESEARCH

Different proliferative and survival capacity of CLL-cells in a newly established in vitro model for pseudofollicles

(2009) M Plander et al.   LEUKEMIA

CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment

(2008) P. E. M. Patten et al.   BLOOD

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential

(2008) Tait D. Shanafelt et al.   BRITISH JOURNAL OF HAEMATOLOGY