Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo
出版年份 2016 全文链接
标题
Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo
作者
关键词
Transcription factors, Colon, Inflammatory bowel disease, Inflammation, Cytokines, Colorectal cancer, Phosphorylation, DNA binding assay
出版物
PLoS One
Volume 11, Issue 9, Pages e0163209
出版商
Public Library of Science (PLoS)
发表日期
2016-09-30
DOI
10.1371/journal.pone.0163209
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs
- (2016) Sebastian Anusha et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway
- (2016) Chakrabhavi Dhananjaya Mohan et al. PLoS One
- Nano-cuprous oxide catalyzed one-pot synthesis of a carbazole-based STAT3 inhibitor: a facile approach via intramolecular C–N bond formation reactions
- (2016) C. P. Baburajeev et al. RSC Advances
- Synthesis of 1,2-benzisoxazole tethered 1,2,3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases, and inducing p21 and tubulin acetylation
- (2015) Nanjundaswamy Ashwini et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma
- (2015) Mahabaleshwaraiah Neelgundmath et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells
- (2015) Hanumantharayappa Bharathkumar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and characterization of novel oxazines and demonstration that they specifically target cyclooxygenase 2
- (2015) V. Srinivas et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Novel synthetic bisbenzimidazole that targets angiogenesis in Ehrlich ascites carcinoma bearing mice
- (2015) Rangaswamy Roopashree et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Screening of quinoline, 1,3-benzoxazine, and 1,3-oxazine-based small molecules against isolated methionyl-tRNA synthetase and A549 and HCT116 cancer cells including an in silico binding mode analysis
- (2015) Hanumantharayappa Bharathkumar et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A Nano-MgO and Ionic Liquid-Catalyzed ‘Green’ Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51)
- (2015) Sebastian Anusha et al. PLoS One
- Development of Novel Triazolo-Thiadiazoles from Heterogeneous “Green” Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors
- (2015) C. P. Baburajeev et al. Scientific Reports
- A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2
- (2015) Nirvanappa C. Anilkumar et al. PLoS One
- The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells
- (2015) Elisabeth J. Walsby et al. Oncotarget
- Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinomain Vitroandin Vivo
- (2014) Chakrabhavi Dhananjaya Mohan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Synthetic Biscoumarins Target Tumor Necrosis Factor-α in Hepatocellular Carcinomain Vitroandin Vivo
- (2014) Hosadurga Kumar Keerthy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small Molecule Targeting Malaria Merozoite Surface Protein-1 (MSP-1) Prevents Host Invasion of Divergent Plasmodial Species
- (2014) Rajesh Chandramohanadas et al. JOURNAL OF INFECTIOUS DISEASES
- Discovery of 6-Phenylpyrimido[4,5-b][1,4]oxazines as Potent and Selective Acyl CoA:Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitors with in Vivo Efficacy in Rodents
- (2014) Brian M. Fox et al. JOURNAL OF MEDICINAL CHEMISTRY
- A New Ibuprofen Derivative Inhibits Platelet Aggregation and ROS Mediated Platelet Apoptosis
- (2014) Kodagahalli S. Rakesh et al. PLoS One
- The complexity of NF-κB signaling in inflammation and cancer
- (2013) Bastian Hoesel et al. Molecular Cancer
- Carbon Monoxide Attenuates Dextran Sulfate Sodium-Induced Colitis via Inhibition of GSK-3βSignaling
- (2013) Md. Jamal Uddin et al. Oxidative Medicine and Cellular Longevity
- Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia
- (2012) Francesca Buontempo et al. CELL CYCLE
- Combination chemotherapy increases cytotoxicity of multiple myeloma cells by modification of nuclear factor (NF)-κB activity
- (2012) Kelley Salem et al. EXPERIMENTAL HEMATOLOGY
- Enhanced Antitumor Effect of Combination Therapy With Gemcitabine and Guggulsterone in Pancreatic Cancer
- (2012) Dong-Won Ahn et al. PANCREAS
- Dextran Sodium Sulfate (DSS) Induces Colitis in Mice by Forming Nano-Lipocomplexes with Medium-Chain-Length Fatty Acids in the Colon
- (2012) Hamed Laroui et al. PLoS One
- Correction: Anti-Tumor Activity of a Novel HS-Mimetic-Vascular Endothelial Growth Factor Binding Small Molecule
- (2012) Kazuyuki Sugahara et al. PLoS One
- Attenuation of LPS-induced apoptosis in NGF-differentiated PC12 cells via NF-κB pathway and regulation of cellular redox status by an oxazine derivative
- (2011) Niloufar Ansari et al. BIOCHIMIE
- Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model
- (2011) Muthu K. Shanmugam et al. INTERNATIONAL JOURNAL OF CANCER
- Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice
- (2011) Muthu K. Shanmugam et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Inhibiting NF-κB activation by small molecules as a therapeutic strategy
- (2010) Subash C. Gupta et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- A small oxazine compound as an anti-tumor agent: A novel pyranoside mimetic that binds to VEGF, HB-EGF, and TNF-α
- (2010) Basappa et al. CANCER LETTERS
- Identification of Novel Scaffolds for IκB Kinase Beta Inhibitor via a High Throughput Screening TR-FRET Assay
- (2010) Kwang-Seok Oh et al. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- Estradiol Suppresses NF- B Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages
- (2010) A. J. Murphy et al. JOURNAL OF IMMUNOLOGY
- NF-κB in inflammatory bowel disease
- (2008) I. Atreya et al. JOURNAL OF INTERNAL MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now