Loss of HIF-1α in the Notochord Results in Cell Death and Complete Disappearance of the Nucleus Pulposus

Advancing the cellular and molecular therapy for intervertebral disc disease

(2015) Daisuke Sakai et al.   ADVANCED DRUG DELIVERY REVIEWS

Evaluation of intervertebral disc cartilaginous endplate structure using magnetic resonance imaging

(2013) Sung M. Moon et al.   EUROPEAN SPINE JOURNAL

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO

(2012) Erinn B. Rankin et al.   CELL

Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes

(2012) Ellinoora Aro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-driven pathways in bone development, regeneration and disease

(2012) Christa Maes et al.   Nature Reviews Rheumatology

Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development

(2011) M. R. McCann et al.   Disease Models & Mechanisms

VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival

(2011) Christa Maes et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs

(2011) K.-S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward an understanding of the role of notochordal cells in the adult intervertebral disc: From discord to accord

(2010) Makarand V. Risbud et al.   DEVELOPMENTAL DYNAMICS

The intervertebral disc: From pathophysiology to tissue engineering

(2009) Johann Clouet et al.   JOINT BONE SPINE

Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc

(2008) Amit Agrawal et al.   ARTHRITIS AND RHEUMATISM

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: Implications for disk degeneration and chordoma formation

(2008) Kyung-Suk Choi et al.   DEVELOPMENTAL DYNAMICS

A mouse line expressing Foxa2-driven Cre recombinase in node, notochord, floorplate, and endoderm

(2008) Lena Uetzmann et al.   GENESIS

Intervertebral Disc: Anatomy-Physiology-Pathophysiology-Treatment

(2008) P. Prithvi Raj   Pain Practice