Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies
出版年份 2013 全文链接
标题
Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies
作者
关键词
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出版物
FASEB JOURNAL
Volume 27, Issue 9, Pages 3424-3429
出版商
FASEB
发表日期
2013-05-17
DOI
10.1096/fj.12-223842
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits
- (2013) Patrick J. Schultheis et al. HUMAN MOLECULAR GENETICS
- Interplay of LRRK2 with chaperone-mediated autophagy
- (2013) Samantha J Orenstein et al. NATURE NEUROSCIENCE
- RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk
- (2013) David A. MacLeod et al. NEURON
- The genetics and neuropathology of Parkinson’s disease
- (2012) Henry Houlden et al. ACTA NEUROPATHOLOGICA
- Mutation of the parkinsonism gene ATP13A2 causes neuronal ceroid-lipofuscinosis
- (2012) Jose Bras et al. HUMAN MOLECULAR GENETICS
- Sphingolipids: regulators of crosstalk between apoptosis and autophagy
- (2012) Megan M. Young et al. JOURNAL OF LIPID RESEARCH
- Development and Characterization of a New Parkinson's Disease Model Resulting from Impaired Autophagy
- (2012) I. Ahmed et al. JOURNAL OF NEUROSCIENCE
- Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, -Synuclein Accumulation, and Neurotoxicity
- (2012) M. Usenovic et al. JOURNAL OF NEUROSCIENCE
- Disrupted Autophagy Leads to Dopaminergic Axon and Dendrite Degeneration and Promotes Presynaptic Accumulation of -Synuclein and LRRK2 in the Brain
- (2012) L. G. Friedman et al. JOURNAL OF NEUROSCIENCE
- Systematic Mutagenesis of -Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
- (2012) J. Burre et al. JOURNAL OF NEUROSCIENCE
- The link between the GBA gene and parkinsonism
- (2012) Ellen Sidransky et al. LANCET NEUROLOGY
- Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway
- (2012) Youren Tong et al. Molecular Neurodegeneration
- Lysosome-dependent pathways as a unifying theme in Parkinson's disease
- (2012) George K. Tofaris MOVEMENT DISORDERS
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration
- (2012) B. Dehay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
- (2011) Alexander Zimprich et al. AMERICAN JOURNAL OF HUMAN GENETICS
- VPS35 Mutations in Parkinson Disease
- (2011) Carles Vilariño-Güell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Acid β-glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α-synuclein processing
- (2011) Valerie Cullen et al. ANNALS OF NEUROLOGY
- SNARE Proteins Are Required for Macroautophagy
- (2011) Usha Nair et al. CELL
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
- (2011) Joseph R. Mazzulli et al. CELL
- Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
- (2011) Patricia Gómez-Suaga et al. HUMAN MOLECULAR GENETICS
- Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism
- (2011) Jin-Sung Park et al. HUMAN MUTATION
- α-Synuclein Interacts with Glucocerebrosidase Providing a Molecular Link between Parkinson and Gaucher Diseases
- (2011) Thai Leong Yap et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing
- (2011) Stefan F. Lichtenthaler et al. JOURNAL OF NEUROCHEMISTRY
- Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains
- (2010) Lydia Alvarez-Erviti et al. ARCHIVES OF NEUROLOGY
- Mitophagy and Parkinson's disease: The PINK1–parkin link
- (2010) Emma Deas et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
- (2010) Kelly Jean Thomas et al. HUMAN MOLECULAR GENETICS
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
- (2010) Mark R. Cookson NATURE REVIEWS NEUROSCIENCE
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders
- (2009) Philipp J. Kahle et al. FREE RADICAL BIOLOGY AND MEDICINE
- LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
- (2009) Javier Alegre-Abarrategui et al. HUMAN MOLECULAR GENETICS
- Parkinson's disease
- (2009) Andrew J Lees et al. LANCET
- Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity
- (2009) Esti Yeger-Lotem et al. NATURE GENETICS
- Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
- (2009) Yaping Chu et al. NEUROBIOLOGY OF DISEASE
- Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
- (2009) Xian Lin et al. NEURON
- Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells
- (2008) Tereza Vogiatzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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