A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation In Vivo and Regulates Urethral Tension
出版年份 2014 全文链接
标题
A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation In Vivo and Regulates Urethral Tension
作者
关键词
Blood plasma, Oral administration, Cholines, Muscle contraction, Pharmacokinetics, Recombinant proteins, Drug administration, Blood
出版物
PLoS One
Volume 9, Issue 4, Pages e93230
出版商
Public Library of Science (PLoS)
发表日期
2014-04-19
DOI
10.1371/journal.pone.0093230
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Autotaxin Production of Lysophosphatidic Acid Mediates Allergic Asthmatic Inflammation
- (2013) Gye Young Park et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Necessity of Lysophosphatidic Acid Receptor 1 for Development of Arthritis
- (2013) Yoshishige Miyabe et al. ARTHRITIS AND RHEUMATISM
- Increased lysophosphatidic acid levels in culprit coronary arteries of patients with acute coronary syndrome
- (2013) Tomotaka Dohi et al. ATHEROSCLEROSIS
- Constitutive Lymphocyte Transmigration across the Basal Lamina of High Endothelial Venules Is Regulated by the Autotaxin/Lysophosphatidic Acid Axis
- (2013) Z. Bai et al. JOURNAL OF IMMUNOLOGY
- Pulmonary Autotaxin Expression Contributes to the Pathogenesis of Pulmonary Fibrosis
- (2012) Nikos Oikonomou et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy
- (2012) David N. Brindley et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis
- (2012) Nigel J. Pyne et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lysophosphatidic acid: Chemical signature of neuropathic pain
- (2012) Hiroshi Ueda et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis
- (2012) Ioanna Nikitopoulou et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Insights into the pharmacological relevance of lysophospholipid receptors
- (2011) Tetsuji Mutoh et al. BRITISH JOURNAL OF PHARMACOLOGY
- Autotaxin and LPA receptor signaling in cancer
- (2011) Anna J. S. Houben et al. CANCER AND METASTASIS REVIEWS
- Non-Edg family LPA receptors: the cutting edge of LPA research
- (2011) K. Yanagida et al. JOURNAL OF BIOCHEMISTRY
- Structural basis of substrate discrimination and integrin binding by autotaxin
- (2011) Jens Hausmann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
- (2011) Hiroshi Nishimasu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Lysophosphatidic Acid Is a Potential Mediator of Cholestatic Pruritus
- (2010) Andreas E. Kremer et al. GASTROENTEROLOGY
- Autotaxin and Lysophosphatidic Acid1 receptor-Mediated Demyelination of Dorsal Root Fibers by Sciatic Nerve Injury and Intrathecal Lysophosphatidylcholine
- (2010) Jun Nagai et al. Molecular Pain
- Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation
- (2010) H. M. H. G. Albers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dual Activity Lysophosphatidic Acid Receptor Pan-Antagonist/Autotaxin Inhibitor Reduces Breast Cancer Cell Migration In vitro and Causes Tumor Regression In vivo
- (2009) Honglu Zhang et al. CANCER RESEARCH
- Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma
- (2008) Akiko Masuda et al. BRITISH JOURNAL OF HAEMATOLOGY
- S32826, A Nanomolar Inhibitor of Autotaxin: Discovery, Synthesis and Applications as a Pharmacological Tool
- (2008) G. Ferry et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
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