High-Risk Human Papillomavirus Targets Crossroads in Immune Signaling

The interferon-related developmental regulator 1 is used by human papillomavirus to suppress NFκB activation

(2015) Bart Tummers et al.   Nature Communications

EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production

(2014) April Kalinowski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cytokine regulation by epidermal growth factor receptor inhibitors and epidermal growth factor receptor inhibitor associated skin toxicity in cancer patients

(2014) Tanusree Paul et al.   EUROPEAN JOURNAL OF CANCER

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Double-Stranded RNA Induces an Antiviral Defense Status in Epidermal Keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-Mediated Differential Signaling

(2014) B. N. Kalali et al.   JOURNAL OF IMMUNOLOGY

E3 ubiquitin ligases and human papillomavirus-induced carcinogenesis

(2014) Zhifeng Lou et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

CD40-Mediated Amplification of Local Immunity by Epithelial Cells Is Impaired by HPV

(2014) Bart Tummers et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HPV16 E2-mediated potentiation of NF-κB activation induced by TNF-α involves parallel activation of STAT3 with a reduction in E2-induced apoptosis

(2014) Devan Prabhavathy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

E2 Proteins of High Risk Human Papillomaviruses Down-Modulate STING and IFN-κ Transcription in Keratinocytes

(2014) Nuchsupha Sunthamala et al.   PLoS One

HPV16 activates the AIM2 inflammasome in keratinocytes

(2013) M. Reinholz et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Genetic variation in the TLR and NF-κB pathways and cervical and vulvar cancer risk: A population-based case-control study

(2013) Clara Bodelon et al.   INTERNATIONAL JOURNAL OF CANCER

The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

(2013) Uzma A. Hasan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human papillomavirus 16-encoded E7 protein inhibits IFN- -mediated MHC class I antigen presentation and CTL-induced lysis by blocking IRF-1 expression in mouse keratinocytes

(2013) F. Zhou et al.   JOURNAL OF GENERAL VIROLOGY

Diseases associated with human papillomavirus infection

(2013) Heather A. Cubie   VIROLOGY

Post-Translational Control of IL-1β via the Human Papillomavirus Type 16 E6 Oncoprotein: A Novel Mechanism of Innate Immune Escape Mediated by the E3-Ubiquitin Ligase E6-AP and p53

(2013) Martina Niebler et al.   PLoS Pathogens

The HPV16 E6 Oncoprotein Causes Prolonged Receptor Protein Tyrosine Kinase Signaling and Enhances Internalization of Phosphorylated Receptor Species

(2013) Jennifer M. Spangle et al.   PLoS Pathogens

Human Papillomavirus (HPV) Upregulates the Cellular Deubiquitinase UCHL1 to Suppress the Keratinocyte's Innate Immune Response

(2013) Rezaul Karim et al.   PLoS Pathogens

Human papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and immortalization

(2012) Erik R. Vandermark et al.   VIROLOGY

SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction

(2012) Hidefumi Fukushima et al.   Cell Reports

Therapeutic vaccination against human papilloma virus induced malignancies

(2011) Sjoerd H van der Burg et al.   CURRENT OPINION IN IMMUNOLOGY

Human papillomavirus 16 E7 protein inhibits interferon-γ-mediated enhancement of keratinocyte antigen processing and T-cell lysis

(2011) Fang Zhou et al.   FEBS Journal

Identification of Key Amino Acid Residues That Determine the Ability of High Risk HPV16-E7 to Dysregulate Major Histocompatibility Complex Class I Expression

(2011) Corina Heller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Keratinocyte sensitization to tumour necrosis factor-induced nuclear factor kappa B activation by the E2 regulatory protein of human papillomaviruses

(2011) M. Boulabiar et al.   JOURNAL OF GENERAL VIROLOGY

p53 Serves as a Host Antiviral Factor That Enhances Innate and Adaptive Immune Responses to Influenza A Virus

(2011) C. Munoz-Fontela et al.   JOURNAL OF IMMUNOLOGY

Human Papillomavirus Type 16 E5 Protein Induces Expression of Beta Interferon through Interferon Regulatory Factor 1 in Human Keratinocytes

(2011) V. Muto et al.   JOURNAL OF VIROLOGY

Suppression of STAT-1 Expression by Human Papillomaviruses Is Necessary for Differentiation-Dependent Genome Amplification and Plasmid Maintenance

(2011) S. Hong et al.   JOURNAL OF VIROLOGY

High-Risk Human Papillomaviruses Repress Constitutive Kappa Interferon Transcription via E6 To Prevent Pathogen Recognition Receptor and Antiviral-Gene Expression

(2011) J. Reiser et al.   JOURNAL OF VIROLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Human Papillomavirus Deregulates the Response of a Cellular Network Comprising of Chemotactic and Proinflammatory Genes

(2011) Rezaul Karim et al.   PLoS One

Immunotherapy for persistent viral infections and associated disease

(2011) Sjoerd H. van der Burg et al.   TRENDS IN IMMUNOLOGY

European Guidelines for Quality Assurance in Cervical Cancer Screening. Second Edition--Summary Document

(2010) M. Arbyn et al.   ANNALS OF ONCOLOGY

NFX1 Plays a Role in Human Papillomavirus Type 16 E6 Activation of NF B Activity

(2010) M. Xu et al.   JOURNAL OF VIROLOGY

CD1d, a Sentinel Molecule Bridging Innate and Adaptive Immunity, Is Downregulated by the Human Papillomavirus (HPV) E5 Protein: a Possible Mechanism for Immune Evasion by HPV

(2010) S. Miura et al.   JOURNAL OF VIROLOGY

Factors affecting transmission of mucosal human papillomavirus

(2010) Nienke J Veldhuijzen et al.   LANCET INFECTIOUS DISEASES

HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells

(2010) M.S. Campo et al.   VIROLOGY

Repression of MHC class I transcription by HPV16E7 through interaction with a putative RXRβ motif and NF-κB cytoplasmic sequestration

(2009) Hui Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Papillomavirus 16 E7 Oncoprotein Attenuates DNA Damage Checkpoint Control by Increasing the Proteolytic Turnover of Claspin

(2009) N. Spardy et al.   CANCER RESEARCH

Epigenetic Silencing of Interferon-  in Human Papillomavirus Type 16-Positive Cells

(2009) B. Rincon-Orozco et al.   CANCER RESEARCH

Keratinocytes efficiently process endogenous antigens for cytotoxic T-cell mediated lysis

(2009) Fang Zhou et al.   EXPERIMENTAL DERMATOLOGY

Viral entry mechanisms: human papillomavirus and a long journey from extracellular matrix to the nucleus

(2009) Martin Sapp et al.   FEBS Journal

Interaction of Bap31 and MHC Class I Molecules and Their Traffic Out of the Endoplasmic Reticulum

(2009) F. Abe et al.   JOURNAL OF IMMUNOLOGY

Inactivation of the CYLD Deubiquitinase by HPV E6 Mediates Hypoxia-Induced NF-κB Activation

(2008) Jiabin An et al.   CANCER CELL

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

(2008) Fulvia Terenzi et al.   EMBO JOURNAL

Transcriptional role of p53 in interferon-mediated antiviral immunity

(2008) César Muñoz-Fontela et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Common Variants in Immune and DNA Repair Genes and Risk for Human Papillomavirus Persistence and Progression to Cervical Cancer

(2008) Sophia S. Wang et al.   JOURNAL OF INFECTIOUS DISEASES

Bap31 Is a Novel Target of the Human Papillomavirus E5 Protein

(2008) J. A. Regan et al.   JOURNAL OF VIROLOGY