Controllability in Cancer Metabolic Networks According to Drug Targets as Driver Nodes

Structure and dynamics of molecular networks: A novel paradigm of drug discovery

(2013) Peter Csermely et al.   PHARMACOLOGY & THERAPEUTICS

QuateXelero: An Accelerated Exact Network Motif Detection Algorithm

(2013) Sahand Khakabimamaghani et al.   PLoS One

Controlling edge dynamics in complex networks

(2012) Tamás Nepusz et al.   Nature Physics

Dominating scale-free networks with variable scaling exponent: heterogeneous networks are not difficult to control

(2012) Jose C Nacher et al.   NEW JOURNAL OF PHYSICS

Control Centrality and Hierarchical Structure in Complex Networks

(2012) Yang-Yu Liu et al.   PLoS One

Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT

(2012) Rasmus Agren et al.   PLoS Computational Biology

Fifteen years of large scale metabolic modeling of yeast: Developments and impacts

(2011) Tobias Österlund et al.   BIOTECHNOLOGY ADVANCES

Codon usage variability determines the correlation between proteome and transcriptome fold changes

(2011) Roberto Olivares-Hernández et al.   BMC Systems Biology

iAB-RBC-283: A proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states

(2011) Aarash Bordbar et al.   BMC Systems Biology

Controllability of complex networks

(2011) Yang-Yu Liu et al.   NATURE

Exploring Off-Targets and Off-Systems for Adverse Drug Reactions via Chemical-Protein Interactome — Clozapine-Induced Agranulocytosis as a Case Study

(2011) Lun Yang et al.   PLoS Computational Biology

Drug Discovery Using Chemical Systems Biology: Weak Inhibition of Multiple Kinases May Contribute to the Anti-Cancer Effect of Nelfinavir

(2011) Li Xie et al.   PLoS Computational Biology

Metabolic genes in cancer: Their roles in tumor progression and clinical implications

(2010) Eiji Furuta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

MIND-BEST: Web Server for Drugs and Target Discovery; Design, Synthesis, and Assay of MAO-B Inhibitors and Theoretical−Experimental Study of G3PDH Protein fromTrichomonas gallinae

(2010) Humberto González-Díaz et al.   JOURNAL OF PROTEOME RESEARCH

HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology

(2010) Christoph Gille et al.   Molecular Systems Biology

Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions

(2010) Aarash Bordbar et al.   Molecular Systems Biology

Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism

(2010) Livnat Jerby et al.   Molecular Systems Biology

Large-scale in silico modeling of metabolic interactions between cell types in the human brain

(2010) Nathan E Lewis et al.   NATURE BIOTECHNOLOGY

A protocol for generating a high-quality genome-scale metabolic reconstruction

(2010) Ines Thiele et al.   Nature Protocols

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Cancer as a metabolic disease

(2010) Thomas N Seyfried et al.   Nutrition & Metabolism

Modeling Core Metabolism in Cancer Cells: Surveying the Topology Underlying the Warburg Effect

(2010) Osbaldo Resendis-Antonio et al.   PLoS One

Drug Off-Target Effects Predicted Using Structural Analysis in the Context of a Metabolic Network Model

(2010) Roger L. Chang et al.   PLoS Computational Biology

Kavosh: a new algorithm for finding network motifs

(2009) Zahra Kashani et al.   BMC BIOINFORMATICS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Slave nodes and the controllability of metabolic networks

(2009) Dong-Hee Kim et al.   NEW JOURNAL OF PHYSICS

How to Turn a Genetic Circuit into a Synthetic Tunable Oscillator, or a Bistable Switch

(2009) Lucia Marucci et al.   PLoS One

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

Network-based prediction of human tissue-specific metabolism

(2008) Tomer Shlomi et al.   NATURE BIOTECHNOLOGY

The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli

(2008) Adam M Feist et al.   NATURE BIOTECHNOLOGY

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Hubba: hub objects analyzer—a framework of interactome hubs identification for network biology

(2008) Chung-Yen Lin et al.   NUCLEIC ACIDS RESEARCH

The implications of human metabolic network topology for disease comorbidity

(2008) D.- S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA