Targeting cancer cells in the tumor microenvironment: opportunities and challenges in combinatorial nanomedicine
出版年份 2015 全文链接
标题
Targeting cancer cells in the tumor microenvironment: opportunities and challenges in combinatorial nanomedicine
作者
关键词
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出版物
Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
Volume 8, Issue 2, Pages 208-222
出版商
Wiley
发表日期
2015-07-07
DOI
10.1002/wnan.1358
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Therapeutic strategies for targeting the ovarian tumor stroma
- (2017) Song Yi Ko et al. World Journal of Clinical Cases
- Controlled Release of a Sparingly Water-Soluble Anticancer Drug through pH-Responsive Functionalized Gold-Nanoparticle-Decorated Liposomes
- (2015) Chandan Adhikari et al. CHEMPHYSCHEM
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- (2015) Satiesh Kumar Ramadass et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Design and evaluation of pH-sensitive liposomes constructed by poly(2-ethyl-2-oxazoline)-cholesterol hemisuccinate for doxorubicin delivery
- (2015) Huan Xu et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Hyperthermia-mediated doxorubicin release from thermosensitive liposomes using MR-HIFU: Therapeutic effect in rabbit Vx2 tumours
- (2015) Robert M. Staruch et al. INTERNATIONAL JOURNAL OF HYPERTHERMIA
- Radionanomedicine: Widened perspectives of molecular theragnosis
- (2015) Dong Soo Lee et al. Nanomedicine-Nanotechnology Biology and Medicine
- Nanoparticles with Precise Ratiometric Co-Loading and Co-Delivery of Gemcitabine Monophosphate and Cisplatin for Treatment of Bladder Cancer
- (2014) Lei Miao et al. ADVANCED FUNCTIONAL MATERIALS
- pH-Responsive polymer-liposomes for intracellular drug delivery and tumor extracellular matrix switched-on targeted cancer therapy
- (2014) Yi-Ting Chiang et al. BIOMATERIALS
- Dextran derivative-based pH-sensitive liposomes for cancer immunotherapy
- (2014) Eiji Yuba et al. BIOMATERIALS
- Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML
- (2014) J. E. Lancet et al. BLOOD
- The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
- (2014) Ruth Scherz-Shouval et al. CELL
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- Safe and efficient pH sensitive tumor targeting modified liposomes with minimal cytotoxicity
- (2014) Lilin Wang et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- pH-sensitive stearoyl-PEG-poly(methacryloyl sulfadimethoxine) decorated liposomes for the delivery of gemcitabine to cancer cells
- (2014) Sara Bersani et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Liposome-based co-delivery of siRNA and docetaxel for the synergistic treatment of lung cancer
- (2014) Mei-Hua Qu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Simultaneous active intracellular delivery of doxorubicin and C6-ceramide shifts the additive/antagonistic drug interaction of non-encapsulated combination
- (2014) Nuno A. Fonseca et al. JOURNAL OF CONTROLLED RELEASE
- Monoclonal antibody-targeted, temperature-sensitive liposomes: In vivo tumor chemotherapeutics in combination with mild hyperthermia
- (2014) Zahraa S. Al-Ahmady et al. JOURNAL OF CONTROLLED RELEASE
- Stimuli-sensitive nanopreparations for combination cancer therapy
- (2014) Aditi Jhaveri et al. JOURNAL OF CONTROLLED RELEASE
- Synergistic Nanoparticulate Drug Combination Overcomes Multidrug Resistance, Increases Efficacy, and Reduces Cardiotoxicity in a Nonimmunocompromised Breast Tumor Model
- (2014) Adam J. Shuhendler et al. MOLECULAR PHARMACEUTICS
- The Combined Effect of Encapsulating Curcumin and C6 Ceramide in Liposomal Nanoparticles against Osteosarcoma
- (2014) Santosh S. Dhule et al. MOLECULAR PHARMACEUTICS
- Initial Therapy with FOLFOXIRI and Bevacizumab for Metastatic Colorectal Cancer
- (2014) Fotios Loupakis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Liposomal Co-Delivery of Omacetaxine Mepesuccinate and Doxorubicin for Synergistic Potentiation of Antitumor Activity
- (2014) Gayong Shim et al. PHARMACEUTICAL RESEARCH
- High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
- (2014) Lesley A. Mathews Griner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways
- (2014) S. W. Morton et al. Science Signaling
- Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
- (2014) Meenakshi Upreti et al. Translational Oncology
- Hyperthermia-Induced Drug Delivery from Thermosensitive Liposomes Encapsulated in an Injectable Hydrogel for Local Chemotherapy
- (2014) Adolfo López-Noriega et al. Advanced Healthcare Materials
- Novel Resveratrol and 5-Fluorouracil Coencapsulated in PEGylated Nanoliposomes Improve Chemotherapeutic Efficacy of Combination against Head and Neck Squamous Cell Carcinoma
- (2014) Aarti Mohan et al. Biomed Research International
- Lipid-Coated Cisplatin Nanoparticles Induce Neighboring Effect and Exhibit Enhanced Anticancer Efficacy
- (2013) Shutao Guo et al. ACS Nano
- Codelivery of mTERT siRNA and paclitaxel by chitosan-based nanoparticles promoted synergistic tumor suppression
- (2013) Wei Wei et al. BIOMATERIALS
- pH-Sensitive nano-systems for drug delivery in cancer therapy
- (2013) Juan Liu et al. BIOTECHNOLOGY ADVANCES
- Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models
- (2013) Pavan P. Adiseshaiah et al. CANCER LETTERS
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- (2013) B. K. Grandhi et al. Cancer Prevention Research
- Topotecan and Doxorubicin Combination to Treat Recurrent Ovarian Cancer: The Influence of Drug Exposure Time and Delivery Systems to Achieve Optimum Therapeutic Activity
- (2013) N. A. Patankar et al. CLINICAL CANCER RESEARCH
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- (2013) Saeed Ghanbarzadeh et al. COLLOIDS AND SURFACES B-BIOINTERFACES
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- (2013) Ishaque M. Shaikh et al. JOURNAL OF CONTROLLED RELEASE
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- (2013) Azadeh Kheirolomoom et al. JOURNAL OF CONTROLLED RELEASE
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- (2013) Li Li et al. JOURNAL OF CONTROLLED RELEASE
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- (2013) Jianan Shen et al. MOLECULAR PHARMACEUTICS
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- (2013) Corbin E. Meacham et al. NATURE
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- (2013) Daniela F Quail et al. NATURE MEDICINE
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- (2013) X. Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Christophoros Mannaris et al. ULTRASOUND IN MEDICINE AND BIOLOGY
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- (2013) Albrecht Neesse et al. OncoTargets and Therapy
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- (2013) L.-C. S. Wang et al. Cancer Immunology Research
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- (2012) A. K. Iyer et al. CURRENT MEDICINAL CHEMISTRY
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- (2012) Rachael M. Crist et al. Integrative Biology
- Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound
- (2012) Holger Grüll et al. JOURNAL OF CONTROLLED RELEASE
- Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
- (2012) Jason Park et al. NATURE MATERIALS
- Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles
- (2011) Hai Wang et al. BIOMATERIALS
- Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer
- (2011) Yixing Jiang et al. CANCER BIOLOGY & THERAPY
- Targeted Therapeutic Remodeling of the Tumor Microenvironment Improves an HER-2 DNA Vaccine and Prevents Recurrence in a Murine Breast Cancer Model
- (2011) D. Liao et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- pH-Sensitive PEGylated Liposomes Functionalized With a Fibronectin-Mimetic Peptide Show Enhanced Intracellular Delivery to Colon Cancer Cells
- (2011) Ashish Garg et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Liposomal encapsulation of a synergistic molar ratio of cytarabine and daunorubicin enhances selective toxicity for acute myeloid leukemia progenitors as compared to analogous normal hematopoietic cells
- (2011) Hyun Pyo Kim et al. EXPERIMENTAL HEMATOLOGY
- Therapeutic targeting of tumor–stroma interactions
- (2011) Stephen Hiscox et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Gemcitabine and tamoxifen-loaded liposomes as multidrug carriers for the treatment of breast cancer diseases
- (2011) D. Cosco et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Hyperthermia-triggered intracellular delivery of anticancer agent to HER2+ cells by HER2-specific affibody (ZHER2-GS-Cys)-conjugated thermosensitive liposomes (HER2+ affisomes)
- (2011) Brandon Smith et al. JOURNAL OF CONTROLLED RELEASE
- Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan
- (2011) Kareen Riviere et al. JOURNAL OF CONTROLLED RELEASE
- Nanomedicine(s) under the Microscope
- (2011) Ruth Duncan et al. MOLECULAR PHARMACEUTICS
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Pharmacokinetics and biodistribution of N-isopropylacrylamide copolymers for the design of pH-sensitive liposomes
- (2009) Nicolas Bertrand et al. BIOMATERIALS
- Safety, Pharmacokinetics, and Efficacy of CPX-1 Liposome Injection in Patients with Advanced Solid Tumors
- (2009) G. Batist et al. CLINICAL CANCER RESEARCH
- Drug ratio-dependent antitumor activity of irinotecan and cisplatin combinations in vitro and in vivo
- (2009) P. G. Tardi et al. MOLECULAR CANCER THERAPEUTICS
- Combining Nanoliposomal Ceramide with Sorafenib Synergistically Inhibits Melanoma and Breast Cancer Cell Survival to Decrease Tumor Development
- (2008) M. A. Tran et al. CLINICAL CANCER RESEARCH
- Rapid Distribution of Liposomal Short-Chain Ceramide in Vitro and in Vivo
- (2008) B. S. Zolnik et al. DRUG METABOLISM AND DISPOSITION
- Recent progress in tumor pH targeting nanotechnology
- (2008) Eun Seong Lee et al. JOURNAL OF CONTROLLED RELEASE
- In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy
- (2008) Paul Tardi et al. LEUKEMIA RESEARCH
- Biodistribution and Pharmacokinetic Analysis of Paclitaxel and Ceramide Administered in Multifunctional Polymer-Blend Nanoparticles in Drug Resistant Breast Cancer Model
- (2008) Lilian E. van Vlerken et al. MOLECULAR PHARMACEUTICS
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