Competing endogenous RNA interplay in cancer: mechanism, methodology, and perspectives

AEG-1 3′-untranslated region functions as a ceRNA in inducing epithelial–mesenchymal transition of human non-small cell lung cancer by regulating miR-30a activity

(2015) Kunmei Liu et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Viral-Human Chimeric Transcript Predisposes Risk to Liver Cancer Development and Progression

(2014) Chi-Chiu Lau et al.   CANCER CELL

FOXO1 3′UTR functions as a ceRNA in repressing the metastases of breast cancer cells via regulating miRNA activity

(2014) Jue Yang et al.   FEBS LETTERS

Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing

(2014) Y. Xu et al.   GENES & DEVELOPMENT

Linc-RNA-RoR acts as a “sponge” against mediation of the differentiation of endometrial cancer stem cells by microRNA-145

(2014) Xi Zhou et al.   GYNECOLOGIC ONCOLOGY

Pseudogene in cancer: real functions and promising signature

(2014) Lu Xiao-Jie et al.   JOURNAL OF MEDICAL GENETICS

Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

(2014) Xiang-hua Liu et al.   Molecular Cancer

Pseudogene PTENP1 Functions as a Competing Endogenous RNA to Suppress Clear-Cell Renal Cell Carcinoma Progression

(2014) G. Yu et al.   MOLECULAR CANCER THERAPEUTICS

Transcriptome-Wide Analysis of UTRs in Non-Small Cell Lung Cancer Reveals Cancer-Related Genes with SNV-Induced Changes on RNA Secondary Structure and miRNA Target Sites

(2014) Radhakrishnan Sabarinathan et al.   PLoS One

The lncRNA-MYC regulatory network in cancer

(2014) Kaiyuan Deng et al.   TUMOR BIOLOGY

BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells

(2014) Xuexia Zhou et al.   Nature Communications

MicroRNAs as a Selective Channel of Communication between Competing RNAs: a Steady-State Theory

(2013) Matteo Figliuzzi et al.   BIOPHYSICAL JOURNAL

MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3

(2013) Guangxian Xu et al.   BMC CANCER

Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver

(2013) Jonathan Schug et al.   BMC GENOMICS

Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma

(2013) Lei Wang et al.   CARCINOGENESIS

RETRACTED: Construction of circular miRNA sponges targeting miR-21 or miR-221 and demonstration of their excellent anticancer effects on malignant melanoma cells

(2013) Yuchen Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Targeting long non-coding RNAs in cancers: Progress and prospects

(2013) Chi Han Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TMPRSS2:ERG Gene Fusion Predicts Subsequent Detection of Prostate Cancer in Patients With High-Grade Prostatic Intraepithelial Neoplasia

(2013) Kyung Park et al.   JOURNAL OF CLINICAL ONCOLOGY

HMGA2 functions as a competing endogenous RNA to promote lung cancer progression

(2013) Madhu S. Kumar et al.   NATURE

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition

(2013) Riccardo Taulli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Growth-Promoting Role of the miR-106a∼363 Cluster in Ewing Sarcoma

(2013) Layne Dylla et al.   PLoS One

Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments

(2013) U. Ala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Circuitous Route to Noncoding RNA

(2013) J. E. Wilusz et al.   SCIENCE

Long noncoding RNA: an emerging paradigm of cancer research

(2013) Man-Tang Qiu et al.   TUMOR BIOLOGY

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

(2013) Ching-Wen Lin et al.   Nature Communications

miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF-1 expression

(2012) Chandi Charan Mandal et al.   CARCINOGENESIS

Identification of RET gene fusion by exon array analyses in “pan-negative” lung cancer from never smokers

(2012) Fei Li et al.   CELL RESEARCH

Decoy activity through microRNAs: the therapeutic implications

(2012) Maria Ines Almeida et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Versican 3′-untranslated region (3′-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity

(2012) Ling Fang et al.   FASEB JOURNAL

The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions

(2012) Z. J. Rutnam et al.   JOURNAL OF CELL SCIENCE

MS2-TRAP (MS2-tagged RNA affinity purification): Tagging RNA to identify associated miRNAs

(2012) Je-Hyun Yoon et al.   METHODS

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Alternative transcription and alternative splicing in cancer

(2012) Sharmistha Pal et al.   PHARMACOLOGY & THERAPEUTICS

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer

(2012) Antonio Lembo et al.   PLoS One

microRNA-21 Governs TORC1 Activation in Renal Cancer Cell Proliferation and Invasion

(2012) Nirmalya Dey et al.   PLoS One

MicroRNA-574-5p Was Pivotal for TLR9 Signaling Enhanced Tumor Progression via Down-Regulating Checkpoint Suppressor 1 in Human Lung Cancer

(2012) Qinchuan Li et al.   PLoS One

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme

(2012) J Lin et al.   Cell Death & Disease

An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma

(2011) Pavel Sumazin et al.   CELL

Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

(2011) Yvonne Tay et al.   CELL

In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma

(2011) Florian A. Karreth et al.   CELL

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

The RNA-binding Protein HuR Opposes the Repression ofERBB-2Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells

(2011) Michael R. Epis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mRNA Stability Factor HuR Inhibits MicroRNA-16 Targeting of COX-2

(2011) L. E. Young et al.   MOLECULAR CANCER RESEARCH

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

Experimental strategies for microRNA target identification

(2011) D. W. Thomson et al.   NUCLEIC ACIDS RESEARCH

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

Emerging Roles for Natural MicroRNA Sponges

(2010) Margaret S. Ebert et al.   CURRENT BIOLOGY

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Expression of CD44 3′-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis

(2010) Zina Jeyapalan et al.   NUCLEIC ACIDS RESEARCH

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

(2010) Jiayi Wang et al.   NUCLEIC ACIDS RESEARCH

Expression of Versican 3′-Untranslated Region Modulates Endogenous MicroRNA Functions

(2010) Daniel Y. Lee et al.   PLoS One

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Cancer-associated regulation of alternative splicing

(2009) Julian P Venables et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites

(2008) N. Li et al.   NUCLEIC ACIDS RESEARCH

Frequency and fate of microRNA editing in human brain

(2008) Y. Kawahara et al.   NUCLEIC ACIDS RESEARCH