KLF10gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients

Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia

(2011) R. E. Ware et al.   BLOOD

Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities

(2011) A. Wilber et al.   BLOOD

The multifunctional role of EKLF/KLF1 during erythropoiesis

(2011) M. Siatecka et al.   BLOOD

Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells

(2011) Inderdeep S. Kalra et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults

(2011) A. E. Gallienne et al.   HAEMATOLOGICA

Genetic Modifiers of Sickle Cell Disease

(2011) Swee Lay Thein   HEMOGLOBIN

Transcription Factors KLF1 and KLF2 Positively Regulate Embryonic and Fetal β-Globin Genes through Direct Promoter Binding

(2011) Yousef N. Alhashem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of Safety and Pharmacokinetics of Sodium 2,2 Dimethylbutyrate, a Novel Short Chain Fatty Acid Derivative, in a Phase 1, Double-Blind, Placebo-Controlled, Single-Dose, and Repeat-Dose Studies in Healthy Volunteers

(2011) Susan P. Perrine et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Evidence for association of anACCN1gene variant with response to lithium treatment in Sardinian patients with bipolar disorder

(2011) Alessio Squassina et al.   PHARMACOGENOMICS

Region-Specific Genetic Heterogeneity ofHBBMutation Distribution in South-Western Greece

(2010) Adamantia Papachatzopoulou et al.   HEMOGLOBIN

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

(2010) Joseph Borg et al.   NATURE GENETICS

The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)

(2009) E. Voskaridou et al.   BLOOD

Hemoglobin research and the origins of molecular medicine

(2008) A. N. Schechter   BLOOD

Pharmacogenomics and Therapeutics of Hemoglobinopathies

(2008) George P. Patrinos et al.   HEMOGLOBIN

Hydroxyurea for the Treatment of Sickle Cell Anemia

(2008) Orah S. Platt   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA