Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities
出版年份 2011 全文链接
标题
Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities
作者
关键词
-
出版物
BLOOD
Volume 117, Issue 15, Pages 3945-3953
出版商
American Society of Hematology
发表日期
2011-02-15
DOI
10.1182/blood-2010-11-316893
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A zinc-finger transcriptional activator designed to interact with the -globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts
- (2010) A. Wilber et al. BLOOD
- Therapeutic levels of fetal hemoglobin in erythroid progeny of -thalassemic CD34+ cells after lentiviral vector-mediated gene transfer
- (2010) A. Wilber et al. BLOOD
- Fetal globin expression is regulated by Friend of Prmt1
- (2010) T. B. van Dijk et al. BLOOD
- c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression
- (2010) E. Bianchi et al. BLOOD
- Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators
- (2010) Nicola K. Wilson et al. Cell Stem Cell
- Update on fetal hemoglobin gene regulation in hemoglobinopathies
- (2010) Daniel E Bauer et al. CURRENT OPINION IN PEDIATRICS
- Transcriptional silencing of -globin by BCL11A involves long-range interactions and cooperation with SOX6
- (2010) J. Xu et al. GENES & DEVELOPMENT
- Networking erythropoiesis: Figure 1.
- (2010) Marc A. Kerenyi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin
- (2010) Joseph Borg et al. NATURE GENETICS
- KLF1 regulates BCL11A expression and γ- to β-globin gene switching
- (2010) Dewang Zhou et al. NATURE GENETICS
- Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation
- (2010) Geneviève Galarneau et al. NATURE GENETICS
- Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease
- (2010) James E. Bradner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Organization of Transcription
- (2010) L. Chakalova et al. Cold Spring Harbor Perspectives in Biology
- Opening act in a hematopoietic program
- (2009) E. Dzierzak BLOOD
- Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program
- (2009) M. Hoogenkamp et al. BLOOD
- SCF induces -globin gene expression by regulating downstream transcription factor COUP-TFII
- (2009) W. Aerbajinai et al. BLOOD
- The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells
- (2009) K. Wahlberg et al. BLOOD
- Control of fetal hemoglobin: new insights emerging from genomics and clinical implications
- (2009) S. L. Thein et al. HUMAN MOLECULAR GENETICS
- Friend of Prmt1, a Novel Chromatin Target of Protein Arginine Methyltransferases
- (2009) T. B. van Dijk et al. MOLECULAR AND CELLULAR BIOLOGY
- Transcription Dynamics
- (2009) Gordon L. Hager et al. MOLECULAR CELL
- Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy
- (2009) Tohru Fujiwara et al. MOLECULAR CELL
- Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis
- (2009) Ming Yu et al. MOLECULAR CELL
- Unknown
- (2009) Maria Gazouli et al. MOLECULAR MEDICINE
- Developmental and species-divergent globin switching are driven by BCL11A
- (2009) Vijay G. Sankaran et al. NATURE
- Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
- (2009) Stefan Schoenfelder et al. NATURE GENETICS
- Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
- (2008) Stuart H. Orkin et al. CELL
- The Alpha Thalassaemias
- (2008) D. R. Higgs et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Of lineage and legacy: the development of mammalian hematopoietic stem cells
- (2008) Elaine Dzierzak et al. NATURE IMMUNOLOGY
- Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of -thalassemia
- (2008) M. Uda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA polymorphisms at the BCL11A, HBS1L-MYB, and -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
- (2008) G. Lettre et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A
- (2008) Vijay G. Sankaran et al. SCIENCE
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