Efficient propagation of variant Creutzfeldt-Jakob disease prion protein using the cell-protein misfolding cyclic amplification technique with samples containing plasma and heparin

High-throughput Analysis of Ultrasonication-forced Amyloid Fibrillation Reveals the Mechanism Underlying the Large Fluctuation in the Lag Time

(2014) Ayaka Umemoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Test for Creutzfeldt–Jakob Disease Using Nasal Brushings

(2014) Christina D. Orrú et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preclinical Detection of Variant CJD and BSE Prions in Blood

(2014) Caroline Lacroux et al.   PLoS Pathogens

Early Detection of Abnormal Prion Protein in Genetic Human Prion Diseases Now Possible Using Real-Time QUIC Assay

(2013) Kazunori Sano et al.   PLoS One

Red-Backed Vole Brain Promotes Highly Efficient In Vitro Amplification of Abnormal Prion Protein from Macaque and Human Brains Infected with Variant Creutzfeldt-Jakob Disease Agent

(2013) Julie Nemecek et al.   PLoS One

Evaluation of a test for its suitability in the diagnosis of variant Creutzfeldt-Jakob disease

(2013) J. K. Cooper et al.   VOX SANGUINIS

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

(2013) O. N. Gill et al.   BMJ-British Medical Journal

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease

(2012) Lynne I. McGuire et al.   ANNALS OF NEUROLOGY

New generation QuIC assays for prion seeding activity

(2012) Christina D. Orru et al.   Prion

The effects of hitchhiker antigens co-eluting with affinity-purified research antibodies

(2011) Lilly Mechetner et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A prototype assay to detect vCJD-infected blood

(2011) Luisa Gregori   LANCET

Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay

(2011) Julie Ann Edgeworth et al.   LANCET

Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion

(2011) Ryuichiro Atarashi et al.   NATURE MEDICINE

Heparin enhances the cell-protein misfolding cyclic amplification efficiency of variant Creutzfeldt–Jakob disease

(2011) Takashi Yokoyama et al.   NEUROSCIENCE LETTERS

Real-time quaking-induced conversion

(2011) Ryuichiro Atarashi et al.   Prion

Estimation of variant Creutzfeldt-Jakob disease infectivity titers in human blood

(2011) Luisa Gregori et al.   TRANSFUSION

Comparison of candidate vCJD in vitro diagnostic assays using identical sample sets

(2011) J. K. Cooper et al.   VOX SANGUINIS

Prion Disease Blood Test Using Immunoprecipitation and Improved Quaking-Induced Conversion

(2011) C. D. Orru et al.   mBio

Species-Dependent Differences in Cofactor Utilization for Formation of the Protease-Resistant Prion Protein in Vitro

(2010) Nathan R. Deleault et al.   BIOCHEMISTRY

Plasminogen stimulates propagation of protease-resistant prion protein in vitro

(2010) Charles E. Mays et al.   FASEB JOURNAL

Cellular factors implicated in prion replication

(2010) Karim Abid et al.   FEBS LETTERS

Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia

(2010) A. PEDEN et al.   HAEMOPHILIA

Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

(2010) Jae-Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimating prion concentration in fluids and tissues by quantitative PMCA

(2010) Baian Chen et al.   NATURE METHODS

Sulfated Dextrans Enhance In Vitro Amplification of Bovine Spongiform Encephalopathy PrPSc and Enable Ultrasensitive Detection of Bovine PrPSc

(2010) Yuichi Murayama et al.   PLoS One

Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification

(2010) M. Howard Tattum et al.   TRANSFUSION

Human variant Creutzfeldt-Jakob disease and sheep scrapie PrPres detection using seeded conversion of recombinant prion protein

(2009) C. D. Orru et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrPSc) associated with variant Creutzfeldt-Jakob disease

(2009) Michael Jones et al.   TRANSFUSION

Prion diseases are efficiently transmitted by blood transfusion in sheep

(2008) F. Houston et al.   BLOOD

Cell-free propagation of prion strains

(2008) Joaquín Castilla et al.   EMBO JOURNAL

In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie

(2008) L. Thorne et al.   JOURNAL OF GENERAL VIROLOGY

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

(2008) Ryuichiro Atarashi et al.   NATURE METHODS