Preclinical Detection of Variant CJD and BSE Prions in Blood

A highly specific blood test for vCJD

(2014) G. S. Jackson et al.   BLOOD

Exploring the zoonotic potential of animal prion diseases

(2014) Marcelo A Barria et al.   Prion

Variant Creutzfeldt-Jakob Disease With Extremely Low Lymphoreticular Deposition of Prion Protein

(2014) Simon Mead et al.   JAMA Neurology

Population Screening for Variant Creutzfeldt-Jakob Disease Using a Novel Blood Test

(2014) Graham S. Jackson et al.   JAMA Neurology

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

(2013) O. N. Gill et al.   BMJ-British Medical Journal

New generation QuIC assays for prion seeding activity

(2012) Christina D. Orru et al.   Prion

Facilitated Cross-Species Transmission of Prions in Extraneural Tissue

(2012) V. Beringue et al.   SCIENCE

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion

(2011) A. H. Peden et al.   JOURNAL OF GENERAL VIROLOGY

Prionemia and Leukocyte-Platelet-Associated Infectivity in Sheep Transmissible Spongiform Encephalopathy Models

(2011) C. Lacroux et al.   JOURNAL OF VIROLOGY

Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay

(2011) Julie Ann Edgeworth et al.   LANCET

In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

(2011) Charles E. Mays et al.   PLoS One

All Clinically-Relevant Blood Components Transmit Prion Disease following a Single Blood Transfusion: A Sheep Model of vCJD

(2011) Sandra McCutcheon et al.   PLoS One

Universal White Blood Cell Reduction in Europe: Has Transmission of Variant Creutzfeldt-Jakob Disease Been Prevented?

(2011) Eleftherios C. Vamvakas   TRANSFUSION MEDICINE REVIEWS

Comparison of candidate vCJD in vitro diagnostic assays using identical sample sets

(2011) J. K. Cooper et al.   VOX SANGUINIS

Accelerated High Fidelity Prion Amplification Within and Across Prion Species Barriers

(2011) Kristi M. Green et al.   PLoS Pathogens

Ultra-Efficient PrPSc Amplification Highlights Potentialities and Pitfalls of PMCA Technology

(2011) Gian Mario Cosseddu et al.   PLoS Pathogens

Atypical/Nor98 Scrapie Infectivity in Sheep Peripheral Tissues

(2011) Olivier Andréoletti et al.   PLoS Pathogens

Sheep and Goat BSE Propagate More Efficiently than Cattle BSE in Human PrP Transgenic Mice

(2011) Danielle Padilla et al.   PLoS Pathogens

Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia

(2010) A. PEDEN et al.   HAEMOPHILIA

B Cells and Platelets Harbor Prion Infectivity in the Blood of Deer Infected with Chronic Wasting Disease

(2010) C. K. Mathiason et al.   JOURNAL OF VIROLOGY

Molecular Interactions between Prions as Seeds and Recombinant Prion Proteins as Substrates Resemble the Biological Interspecies Barrier In Vitro

(2010) Giannantonio Panza et al.   PLoS One

Uncertainty in the Tail of the Variant Creutzfeldt-Jakob Disease Epidemic in the UK

(2010) Tini Garske et al.   PLoS One

Prion Shedding from Olfactory Neurons into Nasal Secretions

(2010) Richard A. Bessen et al.   PLoS Pathogens

Atypical scrapie in sheep from a UK research flock which is free from classical scrapie

(2009) Hugh A Simmons et al.   BMC Veterinary Research

Transmissibility of Atypical Scrapie in Ovine Transgenic Mice: Major Effects of Host Prion Protein Expression and Donor Prion Genotype

(2009) Jean-Noël Arsac et al.   PLoS One

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrPSc) associated with variant Creutzfeldt-Jakob disease

(2009) Michael Jones et al.   TRANSFUSION

Cell-free propagation of prion strains

(2008) Joaquín Castilla et al.   EMBO JOURNAL

In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie

(2008) L. Thorne et al.   JOURNAL OF GENERAL VIROLOGY

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

(2008) Ryuichiro Atarashi et al.   NATURE METHODS

Rodent models for prion diseases

(2008) Martin H. Groschup et al.   VETERINARY RESEARCH

Beyond PrPres Type 1/Type 2 Dichotomy in Creutzfeldt-Jakob Disease

(2008) Emmanuelle Uro-Coste et al.   PLoS Pathogens