New generation QuIC assays for prion seeding activity

Time Course of Prion Seeding Activity in Cerebrospinal Fluid of Scrapie-Infected Hamsters after Intratongue and Intracerebral Inoculations

(2012) C. D. Orru et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion

(2011) A. H. Peden et al.   JOURNAL OF GENERAL VIROLOGY

Prion Disease Detection, PMCA Kinetics, and IgG in Urine from Sheep Naturally/Experimentally Infected with Scrapie and Deer with Preclinical/Clinical Chronic Wasting Disease

(2011) R. Rubenstein et al.   JOURNAL OF VIROLOGY

The Oral Secretion of Infectious Scrapie Prions Occurs in Preclinical Sheep with a Range of PRNP Genotypes

(2011) K. C. Gough et al.   JOURNAL OF VIROLOGY

Detection of Chronic Wasting Disease Prions in Salivary, Urinary, and Intestinal Tissues of Deer: Potential Mechanisms of Prion Shedding and Transmission

(2011) N. J. Haley et al.   JOURNAL OF VIROLOGY

Accelerated Shedding of Prions following Damage to the Olfactory Epithelium

(2011) R. A. Bessen et al.   JOURNAL OF VIROLOGY

Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay

(2011) Julie Ann Edgeworth et al.   LANCET

Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion

(2011) Ryuichiro Atarashi et al.   NATURE MEDICINE

Detection and Localisation of PrPSc in the Liver of Sheep Infected with Scrapie and Bovine Spongiform Encephalopathy

(2011) Sally J. Everest et al.   PLoS One

Real-time quaking-induced conversion

(2011) Ryuichiro Atarashi et al.   Prion

Prion Disease Blood Test Using Immunoprecipitation and Improved Quaking-Induced Conversion

(2011) C. D. Orru et al.   mBio

Highly Efficient Protein Misfolding Cyclic Amplification

(2011) Nuria Gonzalez-Montalban et al.   PLoS Pathogens

A novel method for preclinical detection of PrPSc in blood

(2010) R. Rubenstein et al.   JOURNAL OF GENERAL VIROLOGY

Prions Are Secreted into the Oral Cavity in Sheep with Preclinical Scrapie

(2010) Ben C. Maddison et al.   JOURNAL OF INFECTIOUS DISEASES

B Cells and Platelets Harbor Prion Infectivity in the Blood of Deer Infected with Chronic Wasting Disease

(2010) C. K. Mathiason et al.   JOURNAL OF VIROLOGY

Estimating prion concentration in fluids and tissues by quantitative PMCA

(2010) Baian Chen et al.   NATURE METHODS

Sulfated Dextrans Enhance In Vitro Amplification of Bovine Spongiform Encephalopathy PrPSc and Enable Ultrasensitive Detection of Bovine PrPSc

(2010) Yuichi Murayama et al.   PLoS One

Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification

(2010) M. Howard Tattum et al.   TRANSFUSION

Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays

(2010) Jason M. Wilham et al.   PLoS Pathogens

Protease-Sensitive Synthetic Prions

(2010) David W. Colby et al.   PLoS Pathogens

Prion Shedding from Olfactory Neurons into Nasal Secretions

(2010) Richard A. Bessen et al.   PLoS Pathogens

Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions

(2009) Byron Caughey et al.   Annual Review of Biochemistry

Hyperefficient PrPScamplification of mouse-adapted BSE and scrapie strain by protein misfolding cyclic amplification technique

(2009) Aiko Fujihara et al.   FEBS Journal

Surround optical fiber immunoassay (SOFIA): An ultra-sensitive assay for prion protein detection

(2009) Binggong Chang et al.   JOURNAL OF VIROLOGICAL METHODS

Detection of PrPsc in Blood from Sheep Infected with the Scrapie and Bovine Spongiform Encephalopathy Agents

(2009) L. A. Terry et al.   JOURNAL OF VIROLOGY

Prions Are Secreted in Milk from Clinically Normal Scrapie-Exposed Sheep

(2009) B. C. Maddison et al.   JOURNAL OF VIROLOGY

Immunopurification of Pathological Prion Protein Aggregates

(2009) Emiliano Biasini et al.   PLoS One

Detection of Sub-Clinical CWD Infection in Conventional Test-Negative Deer Long after Oral Exposure to Urine and Feces from CWD+ Deer

(2009) Nicholas J. Haley et al.   PLoS One

Human variant Creutzfeldt-Jakob disease and sheep scrapie PrPres detection using seeded conversion of recombinant prion protein

(2009) C. D. Orru et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrPSc) associated with variant Creutzfeldt-Jakob disease

(2009) Michael Jones et al.   TRANSFUSION

In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie

(2008) L. Thorne et al.   JOURNAL OF GENERAL VIROLOGY

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

(2008) Ryuichiro Atarashi et al.   NATURE METHODS