Osteocyte control of bone remodeling: is sclerostin a key molecular coordinator of the balanced bone resorption–formation cycles?
出版年份 2014 全文链接
标题
Osteocyte control of bone remodeling: is sclerostin a key molecular coordinator of the balanced bone resorption–formation cycles?
作者
关键词
Bone remodeling, FGF23, OPG, Pi, RANKL, Sclerostin
出版物
OSTEOPOROSIS INTERNATIONAL
Volume 25, Issue 12, Pages 2685-2700
出版商
Springer Nature
发表日期
2014-07-16
DOI
10.1007/s00198-014-2808-0
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Bone Matrix Quality After Sclerostin Antibody Treatment
- (2014) Ryan D Ross et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity
- (2013) K.-H. William Lau et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Inactivation of Lrp5 in osteocytes reduces Young's modulus and responsiveness to the mechanical loading
- (2013) Liming Zhao et al. BONE
- Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling
- (2013) Shane A. Lloyd et al. BONE
- Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia
- (2013) Jian Q. Feng et al. BONE
- Effects of Extracellular Phosphate on Gene Expression in Murine Osteoblasts
- (2013) C. Rendenbach et al. CALCIFIED TISSUE INTERNATIONAL
- Osteocyte-Driven Bone Remodeling
- (2013) Teresita Bellido CALCIFIED TISSUE INTERNATIONAL
- Angiogenic factors in bone local environment
- (2013) Shek Man Chim et al. CYTOKINE & GROWTH FACTOR REVIEWS
- RANKL subcellular trafficking and regulatory mechanisms in osteocytes
- (2013) Masashi Honma et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin Regulates Release of Bone Mineral by Osteocytes by Induction of Carbonic Anhydrase 2
- (2013) Masakazu Kogawa et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Single- and Multiple-Dose Randomized Studies of Blosozumab, a Monoclonal Antibody Against Sclerostin, in Healthy Postmenopausal Women
- (2013) Juliet McColm et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Tissue-Level Mechanisms Responsible for the Increase in Bone Formation and Bone Volume by Sclerostin Antibody
- (2013) Michael S Ominsky et al. JOURNAL OF BONE AND MINERAL RESEARCH
- An integrated understanding of the physiological response to elevated extracellular phosphate
- (2013) Corinne E. Camalier et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Early chronic kidney disease–mineral bone disorder stimulates vascular calcification
- (2013) Yifu Fang et al. KIDNEY INTERNATIONAL
- Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial
- (2013) Joy N Tsai et al. LANCET
- WNT signaling in bone homeostasis and disease: from human mutations to treatments
- (2013) Roland Baron et al. NATURE MEDICINE
- Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium
- (2013) Z. C. Ryan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of sclerostin in bone and cartilage and its potential as a therapeutic target in bone diseases
- (2013) E. Michael Lewiecki Therapeutic Advances in Musculoskeletal Disease
- TNF-α mediates the stimulation of sclerostin expression in an estrogen-deficient condition
- (2012) Beom-Jun Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mechanosensation and transduction in osteocytes
- (2012) Jenneke Klein-Nulend et al. BONE
- An overview of the regulation of bone remodelling at the cellular level
- (2012) Jasreen Kular et al. CLINICAL BIOCHEMISTRY
- Phosphate/Pyrophosphate and MV-related Proteins in Mineralisation: Discoveries from Mouse Models
- (2012) Xiaoying Zhou et al. International Journal of Biological Sciences
- Osteocyte RANKL: New insights into the control of bone remodeling
- (2012) Jinhu Xiong et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading
- (2012) Jordan M Spatz et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Roles of Wnt signals in bone resorption during physiological and pathological states
- (2012) Kazuhiro Maeda et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Extracellular phosphate modulates the effect of 1α,25-dihydroxy vitamin D3 (1,25D) on osteocyte like cells
- (2012) Nobuaki Ito et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Higher fibroblast growth factor-23 increases the risk of all-cause and cardiovascular mortality in the community
- (2012) Johan Ärnlöv et al. KIDNEY INTERNATIONAL
- Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis
- (2012) Kazuhiro Maeda et al. NATURE MEDICINE
- Is interaction between age-dependent decline in mechanical stimulation and osteocyte–estrogen receptor levels the culprit for postmenopausal-impaired bone formation?
- (2012) R. Sapir-Koren et al. OSTEOPOROSIS INTERNATIONAL
- Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice
- (2012) Neil Charles Wallace Mackenzie et al. PLoS One
- Targeted deletion of Sost distal enhancer increases bone formation and bone mass
- (2012) N. M. Collette et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting sclerostin as potential treatment of osteoporosis
- (2011) S. E. Papapoulos ANNALS OF THE RHEUMATIC DISEASES
- Disorders of Bone Remodeling
- (2011) Xu Feng et al. Annual Review of Pathology-Mechanisms of Disease
- The sclerostin-bone protein interactome
- (2011) Hemamalini Devarajan-Ketha et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading
- (2011) Xiaolin Tu et al. BONE
- Sirt1 Is a Regulator of Bone Mass and a Repressor ofSostEncoding for Sclerostin, a Bone Formation Inhibitor
- (2011) Einav Cohen-Kfir et al. ENDOCRINOLOGY
- Sostdown-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4
- (2011) Gabriel L. Galea et al. FEBS LETTERS
- Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
- (2011) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism
- (2011) Gerald J Atkins et al. JOURNAL OF BONE AND MINERAL RESEARCH
- DNA methylation contributes to the regulation of sclerostin expression in human osteocytes
- (2011) Jesús Delgado-Calle et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses
- (2011) William F Powell et al. JOURNAL OF ENDOCRINOLOGY
- Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by -Catenin
- (2011) W. Wei et al. MOLECULAR AND CELLULAR BIOLOGY
- Lrp5 functions in bone to regulate bone mass
- (2011) Yajun Cui et al. NATURE MEDICINE
- Matrix-embedded cells control osteoclast formation
- (2011) Jinhu Xiong et al. NATURE MEDICINE
- Evidence for osteocyte regulation of bone homeostasis through RANKL expression
- (2011) Tomoki Nakashima et al. NATURE MEDICINE
- Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered
- (2011) A. Moustafa et al. OSTEOPOROSIS INTERNATIONAL
- Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway
- (2011) Asiri R. Wijenayaka et al. PLoS One
- A sclerostin-based theory for strain-induced bone formation
- (2010) René F. M. van Oers et al. Biomechanics and Modeling in Mechanobiology
- Treatment with a sclerostin antibody increases cancellous bone formation and bone mass regardless of marrow composition in adult female rats
- (2010) XiaoYan Tian et al. BONE
- Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model
- (2010) XiaoYan Tian et al. BONE
- Inhibition of Osteoclastogenesis by Mechanically Loaded Osteocytes: Involvement of MEPE
- (2010) Rishikesh N. Kulkarni et al. CALCIFIED TISSUE INTERNATIONAL
- Sclerostin: Current Knowledge and Future Perspectives
- (2010) M. J. C. Moester et al. CALCIFIED TISSUE INTERNATIONAL
- Suppression of Wnt Signaling by Dkk1 Attenuates PTH-Mediated Stromal Cell Response and New Bone Formation
- (2010) Jun Guo et al. Cell Metabolism
- Are Osteoclasts Needed for the Bone Anabolic Response to Parathyroid Hormone?
- (2010) Dominique D. Pierroz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways
- (2010) Carola Krause et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cellular and Molecular Mechanisms of Bone Remodeling
- (2010) Liza J. Raggatt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
- (2010) Desmond Padhi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Regulation of circulating sclerostin levels by sex steroids in women and in men
- (2010) Ulrike IL Mödder et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The amazing osteocyte
- (2010) Lynda F Bonewald JOURNAL OF BONE AND MINERAL RESEARCH
- Serum Sclerostin Levels Negatively Correlate with Parathyroid Hormone Levels and Free Estrogen Index in Postmenopausal Women
- (2010) Faryal S. Mirza et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Increased Sclerostin Serum Levels Associated with Bone Formation and Resorption Markers in Patients with Immobilization-Induced Bone Loss
- (2010) Agostino Gaudio et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Osteocyte Wnt/ -Catenin Signaling Is Required for Normal Bone Homeostasis
- (2010) I. Kramer et al. MOLECULAR AND CELLULAR BIOLOGY
- Osteocyte: the unrecognized side of bone tissue
- (2010) G. Y. Rochefort et al. OSTEOPOROSIS INTERNATIONAL
- Emerging drugs for postmenopausal osteoporosis
- (2009) E Michael Lewiecki EXPERT OPINION ON EMERGING DRUGS
- Commitment to the Osteoblast Lineage Is Not Required for RANKL Gene Expression
- (2009) Carlo Galli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Local bone formation due to combined mechanical loading and intermittent hPTH-(1-34) treatment and its correlation to mechanical signal distributions
- (2009) M.D. Roberts et al. JOURNAL OF BIOMECHANICS
- Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling
- (2009) Chuwen Lin et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Parathyroid hormone (PTH)–induced bone gain is blunted in SOST overexpressing and deficient mice
- (2009) Ina Kramer et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Is Wnt signalling the final common pathway leading to bone formation?
- (2009) Frances Milat et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- The response of bone to mechanical loading and disuse: Fundamental principles and influences on osteoblast/osteocyte homeostasis
- (2008) Tim M. Skerry ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Osteocytes, mechanosensing and Wnt signaling
- (2008) Lynda F. Bonewald et al. BONE
- The Binding Between Sclerostin and LRP5 is Altered by DKK1 and by High-Bone Mass LRP5 Mutations
- (2008) Wendy Balemans et al. CALCIFIED TISSUE INTERNATIONAL
- Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum
- (2008) Vijay K. Yadav et al. CELL
- NF-κB modulators in osteolytic bone diseases
- (2008) Jiake Xu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- MEPE-ASARM Peptides Control Extracellular Matrix Mineralization by Binding to Hydroxyapatite: An Inhibition Regulated by PHEX Cleavage of ASARM
- (2008) William N Addison et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength
- (2008) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*
- (2008) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate
- (2008) L. Pederson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading
- (2007) Lidan You et al. BONE
- Is BMU-Coupling a Strain-Regulated Phenomenon? A Finite Element Analysis
- (2006) Theo H. Smit et al. JOURNAL OF BONE AND MINERAL RESEARCH
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