Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury

The effects of Dickkopf-1 antibody on metaphyseal bone and implant fixation under different loading conditions

(2011) Fredrik Agholme et al.   BONE

Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression

(2010) G. R. Heiland et al.   ANNALS OF THE RHEUMATIC DISEASES

Wnt modulators in the biotech pipeline

(2010) Jean-Philippe Rey et al.   DEVELOPMENTAL DYNAMICS

Generation and Selection of Novel Fully Human Monoclonal Antibodies That Neutralize Dickkopf-1 (DKK1) Inhibitory Functionin Vitroand Increase Bone Massin Vivo

(2010) Helmut Glantschnig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

(2010) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones

(2010) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocyte Wnt/ -Catenin Signaling Is Required for Normal Bone Homeostasis

(2010) I. Kramer et al.   MOLECULAR AND CELLULAR BIOLOGY

Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints

(2009) S. Uderhardt et al.   ANNALS OF THE RHEUMATIC DISEASES

Dickkopf-1 Enhances Inflammatory Interaction Between Platelets and Endothelial Cells and Shows Increased Expression in Atherosclerosis

(2009) Thor Ueland et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

(2009) M. Fulciniti et al.   BLOOD

Characterization of Wnt/β-catenin signalling in osteoclasts in multiple myeloma

(2009) Ya-Wei Qiang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Wnt signaling in bone metabolism

(2009) Takuo Kubota et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Wnt pathway, an essential role in bone regeneration

(2009) Yan Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V)

(2009) Richard J. Murrills et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Is Wnt signalling the final common pathway leading to bone formation?

(2009) Frances Milat et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

WNT/β-Catenin Signaling Is Involved in Regulation of Osteoclast Differentiation by Human Immunodeficiency Virus Protease Inhibitor Ritonavir

(2008) Rozbeh Modarresi et al.   AMERICAN JOURNAL OF PATHOLOGY

Wnt signaling: A win for bone

(2008) Elke Piters et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The role of Dickkopf-1 in bone development, homeostasis, and disease

(2008) J. J. Pinzone et al.   BLOOD

The Binding Between Sclerostin and LRP5 is Altered by DKK1 and by High-Bone Mass LRP5 Mutations

(2008) Wendy Balemans et al.   CALCIFIED TISSUE INTERNATIONAL

Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo

(2008) Heather E. Fleming et al.   Cell Stem Cell

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma

(2008) Deborah J Heath et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone

(2008) Bart O Williams et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

β-Catenin in the race to fracture repair: in it to Wnt

(2008) David Silkstone et al.   Nature clinical practice. Rheumatology

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma

(2007) Ya-Wei Qiang et al.   BONE